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Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Albumin-to-Globulin Ratio

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A / G

Description

"Albumin-to-Globulin (A/G) Ratio" test compares two essential blood proteins—albumin and globulin—to evaluate liver, kidney, or immune system health. An imbalance in this ratio may indicate chronic inflammation, liver disease, or immune dysfunction. Doctors use a small blood sample to calculate the ratio and guide further testing. It’s often part of broader metabolic panels. Abnormal results help shape treatment plans, from lifestyle adjustments to medical therapy. Tracking this ratio over time supports comprehensive health monitoring and disease prevention.

"Albumin-to-Globulin (A/G) Ratio" test compares two essential blood proteins—albumin and globulin—to evaluate liver, kidney, or immune system health. An imbalance in this ratio may indicate chronic inflammation, liver disease, or immune dysfunction. Doctors use a small blood sample to calculate the ratio and guide further testing. It’s often part of broader metabolic panels. Abnormal results help shape treatment plans, from lifestyle adjustments to medical therapy. Tracking this ratio over time supports comprehensive health monitoring and disease prevention.

Test Category

Proteins

Procedure

Invasive

Sample Type

Blood – Serum

Units

Ratio

Procedure Category

Blood Draw

Test Group

Complete Liver Group, Complete Metabolic Group, Gastrointestinal System Group, Proteins Group

Test Group Description

Complete Liver Group: A thorough array of tests aimed at assessing liver function, providing detailed insights into hepatic health and related conditions. Complete Metabolic Group: A comprehensive suite of tests designed to evaluate metabolic function, offering detailed insights into various aspects of metabolism and associated health conditions. Gastrointestinal Health Group: This group assesses different facets of gastrointestinal function and health, providing insights into digestive well-being and related conditions. Proteins Group: This group comprises tests assessing various aspects of protein levels and function, providing valuable insights into overall protein status and associated health considerations.

Optimal Range

For All Individuals:

  • Conventional Unit: 1.5–2.0 R

  • SI Unit: Not Applicable

Normal Range

For All Individuals:

  • Conventional Unit: 1.1–2.5 R

  • SI Unit: Not Applicable

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Autoimmune diseases (conditions where the immune system mistakenly attacks the body)

  • Bacterial infections (infections caused by bacteria)

  • Dehydration (loss of body fluids)

  • Leukemia (cancer of blood-forming tissues)

  • Liver diseases (various conditions affecting the liver)

  • Low thyroid activit...

Key Reasons For Testing

  • Liver Function Evaluation: Assesses liver health by comparing albumin and globulin levels.

  • Diagnostic Aid in Liver Disease: Identifies conditions like cirrhosis or hepatitis through ratio changes.

  • Assessment of Nutritional Status: Detects malnutrition or protein deficiencies.

  • Inflammatory and Immunological Conditions: Highlights shifts in the ratio linked to autoimmune or inflammatory diseases.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Mutlu EA, Keshavarzian A, Mutlu GM. Hyperalbuminemia and elevated transaminases associated with high-protein diet. Scand J Gastroenterol. 2006;41(6):759-760.
[2] Thakkinstian A, Tran H, Reeves G, et al. A clinical decision rule to aid ordering of serum and urine protein electrophoresis for case-finding of paraproteins in hospitalized inpatients. J Gen Intern Med. 2008;23(10):1688-1692.
[3] Bae JC, Seo SH, Hur KY, et al. Association between serum albumin, insulin resistance, and incident diabetes in nondiabetic subjects. Endocrinol Metab (Seoul). 2013;28(1):26-32.
[4] Cho HM, Kim HC, Lee JM, et al. The association between serum albumin levels and metabolic syndrome in a rural population of Korea. J Prev Med Public Health. 2012;45(2):98-104.
[5] Kadono M, Hasegawa G, Shigeta M, et al. Serum albumin levels predict vascular dysfunction with paradoxical pathogenesis in healthy individuals. Atherosclerosis. 2010;209(1):266-270.
[6] Rahman MZ, Begum BA. Serum total protein, albumin and A/G ratio in different grades of protein energy malnutrition. Mymensingh Med J. 2005;14(1):38-40.
[7] Liu Y, Zhang J, Wang X, et al. Albumin-to-globulin ratio as an independent prognostic indicator in pancreatic cancer patients after surgical resection. Asian Pac J Cancer Prev. 2015;16(16):6893-6898.
[8] Gupta D, Lis CG. Pretreatment serum albumin as a predictor of cancer survival: a systematic review of the epidemiological literature. Nutr J. 2010;9:69.
[9] Walker HK, Hall WD, Hurst JW, editors. Chapter 101 - Serum Albumin and Globulin. In: Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd ed. Boston: Butterworths; 1990.
[10] Hausmann O, Warnatz K. Immunodeficiency in adults: a practical guide for the allergist. Allergo J Int.2014;23(7):261-268.
[11] Jeejeebhoy KN, Boucher BJ, Hartog M. The effect of growth hormone on albumin turnover in man. Metabolism.1965;14:67-74.

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