Apolipoprotein E
APO E
Description
"Apolipoprotein E" (ApoE) test evaluates genetic variants of the ApoE gene, which affect how your body processes fats and influence Alzheimer’s and cardiovascular risk. Doctors may order this test when there’s a family history of memory decline or heart disease. Certain ApoE variants, especially ApoE4, are linked to higher Alzheimer’s risk. Results inform prevention strategies, guide treatment changes, and support early planning. This test plays a key role in personalized risk assessment and long-term brain and heart health.
Category
Proteins, Lipids
Procedure
Invasive
Sample Type
Blood – Plasma
Units
Milligrams Per Deciliter | Grams Per Liter | Not Applicable
Procedure Category
Blood Draw
Test Group
Chronic Illness Group, Complete Cardiovascular Group
Test Group Description
Chronic Illness Group: This group encompasses a range of tests specifically tailored to assess markers associated with chronic health conditions, providing comprehensive insights into the management and monitoring of chronic illnesses.
Optimal Range
For All Individuals:
Conventional Unit: Not Available (ApoE protein level) | APOE4: Negative
SI Unit: Not Available (ApoE protein level) | Not Applicable
Normal Range
For All Individuals:
Conventional Unit: 2.00–5.00 mg/dL (ApoE protein level) | APOE4: Negative
SI Unit: 0.02–0.05 g/L (ApoE protein level) | Not Applicable
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Alzheimer's Disease (Neurodegenerative disorder affecting memory and cognitive function)
Chronic Kidney Disease (Long-term kidney damage)
Chronic Liver Disease (Long-term liver damage)
Cerebrovascular Disease (Disorders affecting blood vessels in the brain)
Familial Hypercholesterolemia (Genetic disorder leading to high c...
Key Reasons For Testing
Cardiovascular Risk Assessment: Evaluates how ApoE variants influence heart disease and clogged artery risk.
Alzheimer’s Disease Risk: Identifies ApoE4 as a genetic marker for increased Alzheimer’s risk.
Lipid Metabolism Regulation: Assesses ApoE’s role in managing cholesterol and fat removal from the blood.
Atherosclerosis and Vascular Health: Examines ApoE’s impact on inflammation and vascular integrity.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
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