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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Blood Urea Nitrogen

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BUN

Description

"Blood Urea Nitrogen" (BUN) test evaluates how well your kidneys are clearing waste by measuring urea nitrogen levels in your blood. It becomes especially important when symptoms like swelling, confusion, or persistent fatigue appear. A rise in BUN may point to dehydration, kidney strain, or heart complications. Low levels could signal liver dysfunction or nutritional imbalance. By clarifying waste filtration status, this test helps guide early interventions and supports ongoing care for kidney, liver, or metabolic conditions.

"Blood Urea Nitrogen" (BUN) test evaluates how well your kidneys are clearing waste by measuring urea nitrogen levels in your blood. It becomes especially important when symptoms like swelling, confusion, or persistent fatigue appear. A rise in BUN may point to dehydration, kidney strain, or heart complications. Low levels could signal liver dysfunction or nutritional imbalance. By clarifying waste filtration status, this test helps guide early interventions and supports ongoing care for kidney, liver, or metabolic conditions.

Test Category

Waste Metabolites

Procedure

Invasive

Sample Type

Blood – Serum

Units

Milligrams Per Deciliter | Millimoles Per Liter

Procedure Category

Blood Draw

Test Group

Basic Kidney Group, Complete Kidney Group, Male Health Group, Female Health Group, Complete Metabolic Group, Basic Metabolic Group, Broad Metabolic Group, Hydration Level Group, Complete Adrenal Group, Gastrointestinal System Group, Cognitive Health Group

Test Group Description

Basic Kidney Group: This group includes tests essential for assessing kidney function and detecting common kidney disorders. Basic Metabolic Group: This set of tests is fundamental for evaluating liver function and detecting common liver disorders. Broad Metabolic Group: This comprehensive set of tests extends beyond the basics, providing a thorough assessment of metabolic health with additional tests beyond the essentials. Cognitive Health Group: This group of tailored tests is aimed at evaluating cognitive function and assessing markers related to cognitive health, providing valuable insights for cognitive well-being and potential cognitive disorders. Complete Adrenal Group: Essential tests for a comprehensive evaluation of adrenal gland function, aiding in the diagnosis and management of adrenal disorders. Complete Kidney Group: Comprehensive tests provide a thorough assessment of kidney function, yielding detailed insights into renal health and associated conditions. Complete Metabolic Group: A comprehensive suite of tests designed to evaluate metabolic function, offering detailed insights into various aspects of metabolism and associated health conditions. Female Health Group: A comprehensive array of tests provides insights into various aspects of female health and wellness, aiding in the evaluation and management of overall health for females. Gastrointestinal Health Group: This group assesses different facets of gastrointestinal function and health, providing insights into digestive well-being and related conditions. Hydration Level Group: By evaluating hydration status and fluid balance, it offers insights into overall hydration levels and related health considerations. Male Health Group: A comprehensive array of tests provides insights into various aspects of male health and wellness, aiding in the evaluation and management of overall health for men.

Optimal Range

For All Individuals:

  • Conventional Unit: 13.00–18.00 mg/dL

  • SI Unit: 4.64–6.43 mmol/L

Normal Range

For All Individuals:

  • Conventional Unit: 6.00–24.00 mg/dL

  • SI Unit: 2.14–8.57 mmol/L

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Burns

  • Congestive heart failure

  • Dehydration (loss of water and electrolytes from the body)

  • High protein intake

  • Kidney disease

  • Myocardial infarction (Heart attack)

  • Nephrotoxic substance use (use of substances that can damage the kidneys)

  • ...

Key Reasons For Testing

  • Kidney Function Assessment: Evaluates kidney performance and detects early signs of kidney problems.

  • Dehydration Evaluation: Identifies fluid imbalances by detecting elevated BUN levels.

  • GI Bleeding Screening: High BUN levels may indicate gastrointestinal bleeding, guiding further investigation.

  • Uremic Symptom Evaluation: Helps diagnose severe uremia-related symptoms like nausea and confusion.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Ramezani A, Massy ZA, Meijers B, Evenepoel P, Vanholder R, Raj DS. Role of the Gut Microbiome in Uremia: A Potential Therapeutic Target. Am J Kidney Dis. 2016;67(3):483-498.
[2] Levey AS, Becker C, Inker LA. Glomerular filtration rate and albuminuria for detection and staging of acute and chronic kidney disease in adults: a systematic review. JAMA. 2015;313(8):837-846.
[3] Thomas ME, Blaine C, Dawnay A, et al. The definition of acute kidney injury and its use in practice. Kidney Int.2015;87(1):62-73.
[4] Santos PW, Lim CH, Qureshi AR, et al. Urea in chronic kidney disease and its relationship with intestinal microbiota and inflammation. Nephrology. 2018;23(8):789-795.
[5] Kalantar-Zadeh K, Kopple JD, Block G, Humphreys MH. A low blood urea nitrogen to creatinine ratio predicts poor outcome in hemodialysis patients. Kidney Int. 2003;63(2):634-641.
[6] Cohen LM, Hooten JN, Shrader KK, et al. Blood urea nitrogen as an index of nutrition in hemodialysis patients. Am J Kidney Dis. 1997;30(5):687-695.
[7] Carlsson AC, Östgren CJ, Nordin M, et al. The association between kidney function and pre-diabetes and insulin resistance in two independent cohorts. Nephrol Dial Transplant. 2015;30(7):1159-1166.
[8] Mitch WE, Ikizler TA. Urea and protein metabolism in chronic kidney disease: from bedside to bench and back. Am J Kidney Dis. 2010;55(6):1054-1067.
[9] Vaziri ND, Wong J, Pahl MV, et al. Chronic kidney disease alters intestinal microbial flora. Kidney Int.2013;83(2):308-315.
[10] Wu IW, Gao SS, Chou FT, et al. Integrative gut microbiota and metabolite profiling in uremia. Toxins (Basel).2015;7(12):4832-4845.
[11] Vanholder R, De Smet R, Glorieux G, et al. Review on uremic toxins: classification, concentration, and interindividual variability. Kidney Int. 2003;63(5):1934-1943.
[12] Kurella Tamura M, Yaffe K, Hsu CY, et al. Cognitive impairment and progression of chronic kidney disease. Am J Kidney Dis. 2016;68(1):77-84.
[13] Saran R, Li Y, Robinson B, et al. US Renal Data System 2015 Annual Data Report: epidemiology of kidney disease in the United States. Am J Kidney Dis. 2016;67(3 Suppl 1):S1-S305.
[14] Amdur RL, Feldman HI, Gupta J, et al. Inflammation and progression of CKD: the CRIC study. Clin J Am Soc Nephrol. 2016;11(9):1546-1556.

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