
Carnitine

CAR
Description
"Carnitine" test measures levels of carnitine, a compound that helps transport fatty acids into cells for energy production. Doctors often order this test when symptoms like muscle weakness, fatigue, or heart problems suggest a metabolic issue. It’s especially useful for identifying carnitine deficiency, malabsorption, or genetic conditions affecting fat metabolism. A blood or urine sample is analyzed to assess carnitine status. Results help guide treatment through dietary adjustments, supplements, or further metabolic testing to restore balance.
Category
Amino Acids
Procedure
Invasive
Sample Type
Blood – Plasma
Units
Micromoles Per Liter
Procedure Category
Blood Draw
Test Group
Metabolite Group
Test Group Description
Metabolite Group: These tests focus on evaluating specific metabolites, offering insights into metabolic function and related health considerations.
Optimal Range
For All Individuals:
Conventional Unit: Free: 40.00–50.00 µmol/L | Total: 50.00–60.00 µmol/L
SI Unit: Free: 40.00–50.00 µmol/L | Total: 50.00–60.00 µmol/L
Normal Range
For All Individuals:
Conventional Unit: Free: 25.00–54.00 µmol/L | Total: 34.00–78.00 µmol/L
SI Unit: Free: 25.00–54.00 µmol/L | Total: 34.00–78.00 µmol/L
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Carnitine palmitoyltransferase 1A deficiency (genetic disorder affecting fatty acid transport into mitochondria)
Decreased levels may indicate:
Primary carnitine deficiency (genetic disorder causing impaired carnitine uptake)
Key Reasons For Testing
Carnitine Deficiency Assessment: Diagnoses deficiencies linked to muscle weakness or metabolic issues by measuring carnitine levels.
Identification of Metabolic Disorders: Detects abnormal levels to uncover mitochondrial diseases or organic acidemias, aiding precise diagnosis.
Monitoring Treatment Response: Tracks levels to evaluate the effectiveness of supplements or therapies addressing deficiencies.
Evaluation of Muscle Function: Assesses energy production and fat metabolism to provide insights into muscle health.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
[1] Bene J, Hadzsiev K, Melegh B. Role of carnitine and its derivatives in the development and management of type 2 diabetes. Nutr Diabetes. 2018;8(1):8.
[2] Steiber A, Kerner J, Hoppel CL. Carnitine: a nutritional, biosynthetic, and functional perspective. Mol Aspects Med.2004;25(5-6):455-473.
[3] Brass EP. Pharmacokinetic considerations for the therapeutic use of carnitine in hemodialysis patients. Clin Ther.1995;17(2):176-185.
[4] Longo N, Amat di San Filippo C, Pasquali M. Disorders of carnitine transport and the carnitine cycle. Am J Med Genet C Semin Med Genet. 2006;142C(2):77-85.
[5] Rebouche CJ, Seim H. Carnitine metabolism and its regulation in microorganisms and mammals. Annu Rev Nutr.1998;18:39-61.
[6] Zammit VA, Ramsay RR, Bonomini M, Arduini A. Carnitine, mitochondrial function, and therapy. Adv Drug Deliv Rev. 2009;61(14):1353-1362.
[7] Mingrone G, Greco AV, Capristo E, et al. L-carnitine improves glucose disposal in type 2 diabetic patients. J Am Coll Nutr. 1999;18(1):77-82.
[8] Evans AM, Fornasini G. Pharmacokinetics of L-carnitine. Clin Pharmacokinet. 2003;42(11):941-967.
[9] Singh RB, Niaz MA, Agarwal P, et al. A randomised, double-blind, placebo-controlled trial of L-carnitine in suspected acute myocardial infarction. Postgrad Med J. 1996;72(844):45-50.
[10] Flanagan JL, Simmons PA, Vehige J, Willcox MD, Garrett Q. Role of carnitine in disease. Nutr Metab (Lond).2010;7:30.
[11] Tanphaichitr V, Leelahagul P. Carnitine metabolism and human carnitine deficiency. Nutrition. 1993;9(3):246-252.
[12] Carter AL, Abney TO, Lapp DF. Biosynthesis and metabolism of carnitine. J Child Neurol. 1995;10(Suppl 2):S3-S7.