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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Creatinine

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CR

Description

"Creatinine" test measures the amount of this waste product in your blood to evaluate kidney filtration and metabolic function. Changes in creatinine levels often show up before kidney disease symptoms fully develop. Elevated readings may indicate reduced kidney performance or blockage, while lower levels can be tied to muscle loss or malnutrition. This test offers critical insight into kidney efficiency. Tracking creatinine over time supports early intervention and helps shape long-term care plans for renal health.

"Creatinine" test measures the amount of this waste product in your blood to evaluate kidney filtration and metabolic function. Changes in creatinine levels often show up before kidney disease symptoms fully develop. Elevated readings may indicate reduced kidney performance or blockage, while lower levels can be tied to muscle loss or malnutrition. This test offers critical insight into kidney efficiency. Tracking creatinine over time supports early intervention and helps shape long-term care plans for renal health.

Category

Waste Metabolites

Procedure

Invasive

Sample Type

Blood – Serum

Units

Milligrams Per Deciliter | Micromoles Per Liter

Procedure Category

Blood Draw

Test Group

Basic Kidney Group, Complete Kidney Group, Male Health Group, Female Health Group, Complete Metabolic Group, Basic Metabolic Group, Broad Metabolic Group, Complete Prostate Group, Gastrointestinal System Group, Cognitive Health Group

Test Group Description

Basic Kidney Group: This group includes tests essential for assessing kidney function and detecting common kidney disorders. Basic Metabolic Group: This set of tests is fundamental for evaluating liver function and detecting common liver disorders. Broad Metabolic Group: This comprehensive set of tests extends beyond the basics, providing a thorough assessment of metabolic health with additional tests beyond the essentials. Cognitive Health Group: This group of tailored tests is aimed at evaluating cognitive function and assessing markers related to cognitive health, providing valuable insights for cognitive well-being and potential cognitive disorders. Complete Kidney Group: Comprehensive tests provide a thorough assessment of kidney function, yielding detailed insights into renal health and associated conditions. Complete Metabolic Group: A comprehensive suite of tests designed to evaluate metabolic function, offering detailed insights into various aspects of metabolism and associated health conditions. Complete Prostate Group: Extensive tests offering a comprehensive assessment of prostate health, providing detailed insights into prostate function and associated conditions. Female Health Group: A comprehensive array of tests provides insights into various aspects of female health and wellness, aiding in the evaluation and management of overall health for females. Gastrointestinal Health Group: This group assesses different facets of gastrointestinal function and health, providing insights into digestive well-being and related conditions. Male Health Group: A comprehensive array of tests provides insights into various aspects of male health and wellness, aiding in the evaluation and management of overall health for men.

Optimal Range

For Men:

  • Conventional Unit: 0.85–1.10 mg/dL

  • SI Unit: 75.14–97.24 µmol/L


For Women:

  • Conventional Unit: 0.65–0.90 mg/dL

  • SI Unit: 57.48–79.56 µmol/L

Normal Range

For Men:

  • Conventional Unit: 0.74–1.35 mg/dL

  • SI Unit: 65.4–119.3 µmol/L


For Women:

  • Conventional Unit: 0.59–1.04 mg/dL

  • SI Unit: 52.2–91.9 µmol/L

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Obstructive urinary tract

  • Kidney damage

  • Azotemia

  • Dehydration

  • Diabetic nephropathy

  • Nephritis

  • Rhabdomyolysis

  • Heart failure (inability of the heart to pump blood effectively)

  • Pyelonephritis [Kidney infection]

  • Pregnancy

  • Intense exercise

  • Particular pharmaceuticals


Decreased levels may indicate:


  • Muscular dystrophy

  • Malnutrition

  • Severe weight loss

  • Debilitation

Key Reasons For Testing

  • Kidney Function: Identifies kidney impairment or dysfunction by measuring elevated creatinine levels.

  • Kidney Disorders: Monitors chronic kidney disease, acute kidney injury, or progression of renal issues.

  • Glomerular Filtration Rate (GFR): Estimates kidney function to assess overall renal health.

  • Dehydration Detection: Highlights elevated creatinine levels caused by dehydration or fluid imbalance.

  • Treatment Monitoring: Tracks creatinine changes to evaluate therapy outcomes or effectiveness.

  • Drug Toxicity: Detects potential kidney damage caused by medications, guiding safe usage.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

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[2] Oh MS, Briefel G. Evaluation of renal function, water, electrolytes, and acid-base balance. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. St Louis, MO: Elsevier; 2017,14.
[3] Perrone RD, Madias NE, Levey AS. Serum creatinine as an index of renal function: new insights into old concepts. Clin Chem. 1992;38(10):1933-1953.
[4] Myers GL, Miller WG, Coresh J, et al. Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program. Clin Chem. 2006;52(1):5-18.
[5] Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney function—measured and estimated glomerular filtration rate. N Engl J Med. 2006;354(23):2473-2483.
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[8] Inker LA, Schmid CH, Tighiouart H, et al. Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med. 2012;367(1):20-29.
[9] Jaffe M. Ueber den Niederschlag welchen Pikrinsaure in normalen Harn erzeugt und uber eine neue Reaction des Kreatinins. Z Physiol Chem. 1886;10:391-400.
[10] Kalantar-Zadeh K, Streja E, Kovesdy CP. Challenges and opportunities in measuring and managing hypercreatininemia in chronic kidney disease. Clin J Am Soc Nephrol. 2009;4(10):1565-1573.
[11] Delanaye P, Cavalier E, Pottel H. Serum creatinine: not so simple! Nephron. 2017;136(4):302-308.
[12] Chen TK, Knicely DH, Grams ME. Chronic kidney disease diagnosis and management: a review. JAMA.2019;322(13):1294-1304.
[13] Lamb EJ, Jones GR, Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. Diagnosis, evaluation, prevention, and treatment of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med. 2013;158(11):825-830.
[14] Schwedt DW, Koehn J, Levine SR. Serum creatinine levels in migraine patients treated with NSAIDs. Headache.2014;54(7):1167-1175.
[15] Waikar SS, Bonventre JV. Creatinine kinetics and the definition of acute kidney injury. J Am Soc Nephrol.2009;20(3):672-679.

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