
Cystatin C

CYSC
Description
"Cystatin C" test measures the level of cystatin C, a protein filtered by the kidneys that reflects kidney function more precisely than creatinine in some cases. It’s especially useful for detecting early kidney damage or assessing cardiovascular risk in people with muscle loss or borderline kidney function. High levels suggest impaired filtration, while stable levels confirm healthy function. Doctors use this test to support individualized care and track changes in kidney or heart health over time.
Test Category
Proteins
Procedure
Invasive
Sample Type
Blood – Serum
Units
Milligrams Per Liter
Procedure Category
Blood Draw
Test Group
Basic Kidney Group, Complete Kidney Group
Test Group Description
Basic Kidney Group: This group includes tests essential for assessing kidney function and detecting common kidney disorders. Complete Kidney Group: Comprehensive tests provide a thorough assessment of kidney function, yielding detailed insights into renal health and associated conditions.
Optimal Range
For All Individuals:
Conventional Unit: Not Available
SI Unit: Not Available
Normal Range
For All Individuals:
Conventional Unit: 0.62–1.15 mg/L
SI Unit: 0.62–1.15 mg/L
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Cancer
Chronic kidney disease
Diabetes (metabolic disorder affecting blood sugar levels)
Heart disease
Heart failure (inability of the heart to pump blood effectively)
Human immunodeficiency virus (Virus causing HIV/AIDS)
Hyperhomocysteinemia (elevated levels of homocysteine in the blood)
Hyperthyroidism (overactive thyroid gland)
Hypothyroidism (underactive thyroid gland)
Key Reasons For Testing
Kidney Function: Estimates GFR to assess renal health, especially in those with low muscle mass.
Early Detection of Kidney Dysfunction: Identifies mild impairment more accurately than creatinine.
CKD Monitoring: Tracks progression of chronic kidney disease over time.
Acute Kidney Injury (AKI): Detects rapid changes in kidney function for timely intervention.
Cardiovascular Risk: Links elevated levels to heart failure, stroke, and coronary disease.
Special Populations: Provides reliable GFR estimates in pediatrics, obesity, or elderly patients.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
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[3] Laterza OF, Price CP, Scott MG. Cystatin C: an improved estimator of glomerular filtration rate? Clin Chem.2002;48(5):699-707.
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[9] Dharnidharka VR, Kwon C, Stevens G. Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am J Kidney Dis. 2002;40(2):221-226.
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[12] Shlipak MG, Sarnak MJ, Katz R, et al. Cystatin C and the risk of death and cardiovascular events among elderly persons. N Engl J Med. 2005;352(20):2049-2060.
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