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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Dehydroepiandrosterone Sulfate

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DHEAS

Description

"Dehydroepiandrosterone Sulfate" (DHEA-S) test checks levels of this adrenal hormone involved in producing estrogen and testosterone. Doctors use it to investigate symptoms like irregular periods, excess hair growth, or hormonal imbalance. Elevated DHEA-S may point to PCOS or adrenal tumors, while low levels can suggest adrenal insufficiency or aging-related decline. A blood sample reveals hormone status and informs care plans. Regular testing helps guide treatment decisions and supports balanced hormone production for metabolic and reproductive health.

"Dehydroepiandrosterone Sulfate" (DHEA-S) test checks levels of this adrenal hormone involved in producing estrogen and testosterone. Doctors use it to investigate symptoms like irregular periods, excess hair growth, or hormonal imbalance. Elevated DHEA-S may point to PCOS or adrenal tumors, while low levels can suggest adrenal insufficiency or aging-related decline. A blood sample reveals hormone status and informs care plans. Regular testing helps guide treatment decisions and supports balanced hormone production for metabolic and reproductive health.

Test Category

Hormones

Procedure

Invasive

Sample Type

Blood – Serum

Units

Micrograms Per Deciliter | Micromoles Per Liter

Procedure Category

Blood Draw

Test Group

Hormone Health Group, Male Health Group, Female Health Group, Complete Adrenal Group, Complete Sex Hormone Group

Test Group Description

Complete Adrenal Group: Essential tests for a comprehensive evaluation of adrenal gland function, aiding in the diagnosis and management of adrenal disorders. Complete Sex Hormone Group: This comprehensive panel offers an extensive evaluation of sex hormone status and reproductive health, providing detailed insights into hormonal balance and function. Female Health Group: A comprehensive array of tests provides insights into various aspects of female health and wellness, aiding in the evaluation and management of overall health for females. Hormone Health Group: Its focus is on evaluating hormone levels and function, providing insights into hormonal balance and associated health conditions. Male Health Group: A comprehensive array of tests provides insights into various aspects of male health and wellness, aiding in the evaluation and management of overall health for men.

Optimal Range

For Men:

  • Conventional Unit: 200.00–450.00 mcg/dL

  • SI Unit: 5.40–12.15 µmol/L


For Women:

  • Conventional Unit: 150.00–250.00 mcg/dL

  • SI Unit: 4.05–6.75 µmol/L

Normal Range

For Men:


Ages 18–19 years:

  • Conventional Unit: 108.00–441.00 mcg/dL

  • SI Unit: 2.92–11.94 µmol/L

Ages 20–29 years:

  • Conventional Unit: 280.00–640.00 mcg/dL

  • SI Unit: 7.56–17.28 µmol/L

Ages 30–39 years:...

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Adrenal cancer

  • Adrenal tumors

  • Alcoholism

  • Chronic stress

  • Congenital adrenal hyperplasia (Genetic disorder affecting adrenal gland function)

  • Cushing's disease (Hypersecretion of cortisol due to pituitary tumor)

  • Excessive dietary supplementation

  • ...

Key Reasons For Testing

  • Endocrine Function: Evaluates adrenal gland health and overall hormonal balance using DHEA-S levels.

  • Aging Marker: Tracks age-related declines, providing insights into healthy aging strategies and potential interventions.

  • Stress Response: Assesses DHEA-S's role in modulating cortisol and enhancing stress resilience.

  • Androgen Precursor: Offers insights into testosterone production, libido, and sexual health...

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Haddad NG, Eugster EA. Precocious puberty. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016,121.
[2] Nakamoto J. Endocrine testing. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016,154.
[3] Nerenz RD, Jungheim E, Gronowski AM. Reproductive endocrinology and related disorders. In: Rifai N, ed. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. St Louis, MO: Elsevier; 2018,68.
[4] Rosenfield RL, Barnes RB, Ehrmann DA. Hyperandrogenism, hirsutism, and polycystic ovary syndrome. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016,133.
[5] van den Beld AW, Lamberts SWJ. Endocrinology and aging. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020,28.
[6] Parker LN. Adrenarche. Endocrinol Metab Clin North Am. 1991;20(1):71-83.
[7] Labrie F, Luu-The V, Bélanger A, et al. Is dehydroepiandrosterone a hormone? J Endocrinol. 2005;187(2):169-196.
[8] Handelsman DJ, Starcevic B, Heather AK, McGregor E. Testicular function and dehydroepiandrosterone sulfate levels in men. Clin Endocrinol (Oxf). 1989;31(6):661-670.
[9] Labrie F, Bélanger A, Luu-The V, et al. DHEA and DHEA-S as physiological and replacement therapy. J Steroid Biochem Mol Biol. 2006;100(4-5):177-188.
[10] Cameron DR, Braunstein GD. Androgen replacement therapy in women. Fertil Steril. 2004;82(2):273-289.
[11] Laughlin GA, Barrett-Connor E. Sexual dimorphism in the influence of advanced aging on adrenal hormone levels: the Rancho Bernardo Study. J Clin Endocrinol Metab. 2000;85(10):3561-3568.
[12] Burger HG. Androgen production in women. Fertil Steril. 2002;77(Suppl 4).
[13] van Niekerk JK, Huppert FA, Herbert J. Salivary DHEA and cortisol: interrelations in a large middle-aged sample. Psychoneuroendocrinology. 2001;26(6):591-607.
[14] Kroboth PD, Salek FS, Pittenger AL, Fabian TJ, Frye RF. DHEA and DHEA-S: a review. J Clin Pharmacol.1999;39(4):327-348.
[15] Ravaglia G, Forti P, Maioli F, et al. Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population. Exp Gerontol. 2002;37(5):701-712.
[16] Arlt W, Justl HG, Callies F, et al. Oral dehydroepiandrosterone replacement therapy in women with adrenal insufficiency: effects on hormone levels and metabolism. J Clin Endocrinol Metab. 1998;83(12):3895-3902.

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