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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Docosapentaenoic Acid

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DPA

Description

"Docosapentaenoic Acid" (DPA) test evaluates blood levels of this long-chain omega-3 fat involved in reducing inflammation and protecting cardiovascular health. It’s useful for identifying omega-3 deficiencies or monitoring supplement use. Doctors often recommend this test for individuals with dietary concerns, chronic inflammation, or elevated cardiovascular risk. Low levels may increase inflammation risk, while high levels could reflect excess supplementation. Results help fine-tune nutritional strategies. This test informs ongoing care focused on heart and inflammatory health.

"Docosapentaenoic Acid" (DPA) test evaluates blood levels of this long-chain omega-3 fat involved in reducing inflammation and protecting cardiovascular health. It’s useful for identifying omega-3 deficiencies or monitoring supplement use. Doctors often recommend this test for individuals with dietary concerns, chronic inflammation, or elevated cardiovascular risk. Low levels may increase inflammation risk, while high levels could reflect excess supplementation. Results help fine-tune nutritional strategies. This test informs ongoing care focused on heart and inflammatory health.

Category

Fatty Acids

Procedure

Invasive

Sample Type

Blood – Whole Blood

Units

Percentage

Procedure Category

Blood Draw

Test Group

Fatty Acid Group, Omega Fatty Acid Group

Test Group Description

Fatty Acid Group: Evaluates fatty acid levels, offering insights into lipid metabolism and associated health conditions. Omega Fatty Acid Group: By evaluating the levels of essential omega fatty acids, this group provides insights into their presence and balance in the body, crucial for supporting cardiovascular health, brain function, and inflammation regulation.

Optimal Range

For All Individuals:

  • Conventional Unit: Not Available

  • SI Unit: Not Available

Normal Range

For All Individuals:

  • Conventional Unit: 0.45–1.80 %

  • SI Unit: Not Frequently Used

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Aging

  • Diabetes (Metabolic disorder characterized by high blood sugar levels)

  • Genetic factors (Inherited traits affecting DPA metabolism)

  • High dietary intake (Consuming foods rich in DPA)

  • Omega-3 supplementation


Decreased levels ...

Key Reasons For Testing

  • Nutritional Assessment: Reflects omega-3 intake and absorption from the diet.

  • Omega-3 Metabolism: Provides insights into how the body processes omega-3 fatty acids.

  • Cardiovascular Health: Supports heart health by lowering triglycerides and reducing inflammation.

  • Inflammatory Response: Modulates immune function to manage inflammation effectively.

  • Brain Health: Promotes cognitive function and neurological development.

  • Eye Health: Maintains retina integrity and supports vision.

  • Pregnancy Support: Ensures adequate DPA for fetal brain and eye development.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Kaur G, Cameron-Smith D, Sinclair AJ, Barr DP. Docosapentaenoic acid (22:5n-3): A review of its biological effects. Prog Lipid Res. 2011;50(1):28-34.
[2] Dyall SC. Long-chain omega-3 fatty acids and the brain: A review of the independent and shared effects of EPA, DPA, and DHA. Front Aging Neurosci. 2015;7:52.
[3] Crowe FL, Skeaff CM, Green TJ, Gray AR. Serum phospholipid n-3 long-chain polyunsaturated fatty acids and physical and mental health in a population-based survey of New Zealand adolescents and adults. Am J Clin Nutr.2007;86(5):1278-1285.
[4] Schuchardt JP, Huss M, Stauss-Grabo M, Hahn A. Significance of long-chain polyunsaturated fatty acids (PUFAs) for the development and behaviour of children. Eur J Pediatr. 2010;169(2):149-164.
[5] Harris WS, Poston WC, Haddock CK. Tissue n-3 and n-6 fatty acids and risk for coronary heart disease events. Atherosclerosis. 2007;193(1):1-10.
[6] Lagarde M, Bernoud N, Brossard N, et al. Lysophosphatidylcholines as a preferential carrier form of docosahexaenoic acid to the brain. J Mol Neurosci. 2001;16(2-3):201-204.
[7] Marangoni F, Angeli MT, Colli S, Colombo C, Poli A, Galli C. Changes of docosapentaenoic acid after n-3 polyunsaturated fatty acid supplementation in humans: a systematic review. Nutrients. 2020;12(4):1147.
[8] Albert BB, Cameron-Smith D, Hofman PL, Cutfield WS. Oxidation of "fishy" fatty acids in children: Kinetics and implications for dietary intake. Nutrients. 2013;5(3):948-961.
[9] Conquer JA, Holub BJ. Docosapentaenoic acid is the major plasma n-3 polyunsaturated fatty acid in responders to fish oil. Prostaglandins Leukot Essent Fatty Acids. 1997;56(1):83-84.
[10] Givens DI, Gibbs RA. Current intakes of EPA and DHA in European populations and the potential of animal-derived foods to increase them. Proc Nutr Soc. 2008;67(3):273-280.
[11] O'Connell TD, Block RC, Huang SP, Shearer GC. ω3-Polyunsaturated fatty acids for heart failure: effects of dose on efficacy and safety. J Am Coll Cardiol. 2015;66(24):2590-2601.
[12] Kremmyda LS, Tvrzicka E, Stankova B, Zak A. Fatty acids as biocompounds: Their role in human metabolism, health and disease – a review. Part 2: Fatty acid physiological roles and applications in human health and disease. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011;155(3):195-218.
[13] Calder PC. Omega-3 polyunsaturated fatty acids and inflammatory processes: Nutrition or pharmacology? Br J Clin Pharmacol. 2013;75(3):645-662.
[14] Wood KE, Mantzioris E, Gibson RA, Ramsden CE, Muhlhausler BS. The role of docosapentaenoic acid (DPA) in human health. Nutrients. 2021;13(1):52.
[15] Lemaitre RN, Tanaka T, Tang W, et al. Genetic loci associated with circulating levels of very long-chain saturated fatty acids. J Lipid Res. 2015;56(1):176-184.

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