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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Estradiol

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E2

Description

"Estradiol" test measures the level of estradiol, a key form of estrogen, to evaluate reproductive and hormonal health. Doctors may order this test to investigate symptoms like irregular periods, infertility, or signs of menopause or PCOS. Abnormal levels may reflect ovarian dysfunction, hormone therapy effects, or menopause-related shifts. Results help clarify hormonal imbalances and inform treatment strategies. Whether you're trying to conceive or managing hormone-related symptoms, estradiol monitoring offers insight into your cycle and overall hormonal balance.

"Estradiol" test measures the level of estradiol, a key form of estrogen, to evaluate reproductive and hormonal health. Doctors may order this test to investigate symptoms like irregular periods, infertility, or signs of menopause or PCOS. Abnormal levels may reflect ovarian dysfunction, hormone therapy effects, or menopause-related shifts. Results help clarify hormonal imbalances and inform treatment strategies. Whether you're trying to conceive or managing hormone-related symptoms, estradiol monitoring offers insight into your cycle and overall hormonal balance.

Test Category

Hormones

Procedure

Invasive

Sample Type

Blood – Serum

Units

Picograms Per Milliliter | Picomoles Per Liter

Procedure Category

Blood Draw

Test Group

Hormone Health Group, Female Hormone Group, Male Health Group, Female Health Group, Complete Cardiovascular Group, Basic Sex Hormone Group, Complete Sex Hormone Group

Test Group Description

Basic Sex Hormone Group: This collection of tests provides fundamental insights into sex hormone levels and reproductive health, offering essential information for hormonal balance assessment. Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments. Complete Sex Hormone Group: This comprehensive panel offers an extensive evaluation of sex hormone status and reproductive health, providing detailed insights into hormonal balance and function. Female Health Group: A comprehensive array of tests provides insights into various aspects of female health and wellness, aiding in the evaluation and management of overall health for females. Female Hormone Group: It assesses hormone levels specific to female health, providing insights into reproductive function and hormonal balance. Hormone Health Group: Its focus is on evaluating hormone levels and function, providing insights into hormonal balance and associated health conditions. Male Health Group: A comprehensive array of tests provides insights into various aspects of male health and wellness, aiding in the evaluation and management of overall health for men. Male Hormone Group: It focuses on assessing hormone levels specific to male health, providing insights into reproductive function and hormonal balance.

Optimal Range

Men:

  • Conventional Unit: 20.0–40.0 pg/mL

  • SI Unit: 73.4–146.8 pmol/L


Women:

  • Conventional Unit: 80.0–200.0 pg/mL

  • SI Unit: 293.6–734.4 pmol/L

Normal Range

Men:

  • Conventional Unit: 7.6–42.6 pg/mL | SI Unit: 27.9–156.3 pmol/L


Women:

  • Conventional Unit: 43.8–211.0 pg/mL (Pre-menopause) | 0.0–31.0 pg/mL (Post-menopause)

  • SI Unit: 160.7–774.2 pmol/L (Pre-menopause) | 0.0–113.8 pmol/L (Post-menopause)

Results That Differ From The Norm (Direct and Indirect Causes)

Abnormal results may indicate:


  • Amenorrhea (Absence of menstruation)

  • Girlhood precocious puberty (Early onset of puberty in girls, before the age of 8)

  • Gynecomastia (Enlargement of breast tissue in males)

  • Klinefelter's syndrome (Genetic condition in males characterized by an extra X chromosome)

  • Low body fat percentage

  • Ovarian hypofunction (Decreased function of the ovaries, leading to reduced estrogen production)

  • Rapid weight reduction

  • Turner's syndrome (Genetic condition in females characterized by missing or incomplete X chromosome)

Key Reasons For Testing

  • Hormonal Assessment: Measures estradiol levels, a key estrogen hormone, in the blood.

  • Reproductive Health: Evaluates menstrual cycles, fertility, and menopausal status.

  • Menopause Transition: Guides staging and hormone therapy decisions.

  • Bone Health: Assesses osteoporosis risk due to estradiol's role in bone density.

  • Endocrine Disorders: Detects conditions like PCOS or estrogen-related tumors.

  • Breast Cancer Risk: Aids in risk assessment and treatment planning.

  • Hormone Therapy Monitoring: Tracks hormone therapy in menopausal or transgender individuals.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Simpson ER. Sources of estrogen and their importance. J Steroid Biochem Mol Biol. 2003;86(3-5):225-230.
[2] Nelson LR, Bulun SE. Estrogen production and action. J Am Acad Dermatol. 2001;45(3 Suppl).
[3] Santoro N, Randolph JF Jr. Reproductive hormones and the menopause transition. Obstet Gynecol Clin North Am.2011;38(3):455-466.
[4] Fogle RH, Stanczyk FZ, Zhang X, Paulson RJ. Ovarian androgen production in postmenopausal women. J Clin Endocrinol Metab. 2007;92(8):3040-3043.
[5] Schmidt PJ, Haq N, Rubinow DR. A longitudinal evaluation of the relationship between reproductive status and mood in perimenopausal women. Am J Psychiatry. 2004;161(12):2238-2244.
[6] Manson JE, Bassuk SS. Menopausal hormone therapy and risk of cardiovascular disease: a patient-centered approach. Ann Intern Med. 2007;146(7):533-536.
[7] Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA.2002;288(3):321-333.
[8] Santen RJ, Allred DC, Ardoin SP, et al. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J Clin Endocrinol Metab. 2010;95(7 Suppl 1).
[9] Brinton RD. The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications. Trends Neurosci. 2008;31(10):529-537.
[10] Vermeulen A, Kaufman JM, Goemaere S, van Pottelbergh I. Estradiol in elderly men. Aging Male. 2002;5(2):98-102.
[11] Sowers MR, Zheng H, McConnell D, et al. Estradiol rates of change in relation to the final menstrual period in a population-based cohort of women. J Clin Endocrinol Metab. 2008;93(10):3847-3852.

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