Estriol
E3
Description
"Estriol" test measures levels of this estrogen produced during pregnancy to monitor fetal development and maternal health. It’s often included in prenatal screening panels to assess the risk of conditions like Down syndrome or identify potential complications. Low estriol may indicate placental or fetal adrenal concerns, while elevated levels can suggest hormonal imbalance or rare disorders. Results provide insight into pregnancy progression. This test supports tailored prenatal care and helps guide next steps in high-risk or routine pregnancies.
Test Category
Hormones
Procedure
Non-Invasive
Sample Type
Saliva
Units
Nanograms Per Milliliter | Nanomoles Per Liter
Procedure Category
Swab
Test Group
Female Hormone Group
Test Group Description
Female Hormone Group: It assesses hormone levels specific to female health, providing insights into reproductive function and hormonal balance. Male Hormone Group: It focuses on assessing hormone levels specific to male health, providing insights into reproductive function and hormonal balance.
Optimal Range
Men:
Conventional Unit: Not Available | SI Unit: Not Available
Women:
Conventional Unit: Not Available (Not Pregnant) | SI Unit: Not Available
Conventional Unit: Not Available (First Trimester) | SI Unit: Not Available
Conventional Unit: Not Available (Second Trimester) | SI Unit: Not Available
Conventional Unit: Not Available (Third Trimester) | SI Unit: Not Available
Normal Range
Men:
Conventional Unit: 0.00–0.18 ng/mL | SI Unit: 0.00–0.62 nmol/L
Women:
Conventional Unit: 0.00–0.21 ng/mL (Not Pregnant) | SI Unit: 0.00–0.72 nmol/L
Conventional Unit: 0.00–2.50 ng/mL (First Trimester) | SI Unit: 0.00–8.66 nmol/L
Conventional Unit: 0.00–9.60 ng/mL (Second Trimester) | SI Unit: 0.00–33.26 nmol/L
Conventional Unit: 0.00–14.60 ng/mL (Third Trimester) | SI Unit: 0.00–50.60 nmol/L
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Late-stage pregnancy
Decreased levels may indicate:
Adrenal insufficiency (Inadequate production of hormones by the adrenal glands)
Aromatase deficiency (Impaired conversion of androgens to estrogens)
Congenital adrenal hyperplasia (Genetic disorder affecting adrenal gland function)
Corticosteroid treatments (Use of medications that suppress adrenal function)
Medications (such as the hyperthyroidism medication Propylthiouracil)
Pregnancy complications
Key Reasons For Testing
Hormonal Assessment: Measures estriol levels, an estrogen type, in blood or urine.
Pregnancy Monitoring: Tracks estriol to assess placental function and fetal health.
Fetal Well-being: Indicates fetal adrenal and liver activity, aiding in developmental assessments.
Preterm Labor Risk: Low third-trimester estriol levels signal increased preterm labor risk.
Menopausal Status: Estriol levels help evaluate menopausal transition and status.
Hormone Therapy Monitoring: Tracks estriol in menopause treatment for safety and effectiveness.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
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[3] Borstein J, Hobbins JC, Dumez Y, Mahoney MJ. The biochemical monitoring of estriol levels in high-risk pregnancy. Am J Obstet Gynecol. 1979;135(6):713-719.
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