top of page

Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

lab-scientists-blood-urine-test-analysis

Fibrinogen

extraction-plasma-from-blood

FG

Description

"Fibrinogen" test evaluates the level of fibrinogen in your blood, a protein critical for clotting and inflammation response. It’s used to assess clotting disorders, liver function, or conditions involving chronic inflammation or vascular stress. High levels may signal infection or cardiovascular risk, while low levels could point to bleeding disorders or liver disease. Doctors interpret these results to shape diagnosis and guide treatment strategies. Ongoing monitoring supports clotting stability and provides insight into inflammatory conditions that affect vascular health.

"Fibrinogen" test evaluates the level of fibrinogen in your blood, a protein critical for clotting and inflammation response. It’s used to assess clotting disorders, liver function, or conditions involving chronic inflammation or vascular stress. High levels may signal infection or cardiovascular risk, while low levels could point to bleeding disorders or liver disease. Doctors interpret these results to shape diagnosis and guide treatment strategies. Ongoing monitoring supports clotting stability and provides insight into inflammatory conditions that affect vascular health.

Test Category

Glycoproteins, Proteins, Clotting Factors

Procedure

Invasive

Sample Type

Blood – Plasma

Units

Milligrams Per Deciliter | Grams Per Liter

Procedure Category

Blood Draw

Test Group

Complete Cardiovascular Group, Coagulation Group, Basic Inflammation Group, Complete Inflammation Group

Test Group Description

Basic Inflammation Group: This set of tests helps evaluate the body's inflammatory response, providing valuable information for diagnosing and managing inflammatory conditions. Coagulation Group: These targeted tests are designed to assess clotting factors and coagulation pathways, offering valuable insights into hemostasis and thrombotic disorders. Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments. Complete Inflammation Group: Extensive tests offer a comprehensive assessment of inflammatory markers, yielding detailed insights into inflammation levels and related health conditions.

Optimal Range

For All Individuals:

  • Conventional Unit: 175–300 mg/dL

  • SI Unit: 1.75–3.00 g/L

Normal Range

For All Individuals:

  • Conventional Unit: 200–400 mg/dL

  • SI Unit: 2.00–4.00 g/L

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Acute stress (Physiological response to sudden stressors)

  • Cancer

  • Heart disease

  • Infections (Bacterial, viral, or fungal infections)

  • Inflammation

  • Ischemic stroke (Stroke caused by a blockage of blood flow to the brain)

  • Myocardial infarction (Heart attack)

    ...

Key Reasons For Testing

  • Clotting Protein: Fibrinogen, made in the liver, is vital for blood clot formation and hemostasis.

  • Structural Role in Clots: Converts to fibrin to stabilize platelet aggregates during coagulation.

  • Inflammation Marker: Levels rise during acute-phase responses to inflammation, infection, or tissue damage.

  • Thrombotic Risk Indicator: Elevated levels signal higher risk of DVT, PE, or arterial thrombosis.

  • Coagulation Disorders: Diagnoses fibrinogen deficiencies and acquired abnormalities like DIC.

  • Fibrinolytic Therapy Monitoring: Tracks therapy efficacy in dissolving clots and restoring flow.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Chernecky CC, Berger BJ. Fibrinogen (factor I) - plasma. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:525.
[2] Pai M. Laboratory evaluation of hemostatic and thrombotic disorders. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:129.
[3] Mackie IJ, Kitchen S, Machin SJ, Lowe GD. Guidelines on fibrinogen assays. Br J Haematol. 2003;121(3):396-404.
[4] Mosesson MW. Fibrinogen and fibrin structure and functions. J Thromb Haemost. 2005;3(8):1894-1904.
[5] Undas A, Ariëns RA. Fibrin clot structure and function: a role in the pathophysiology of arterial and venous thromboembolic diseases. Arterioscler Thromb Vasc Biol. 2011;31(12):e88-e99.
[6] Dunn EJ, Ariëns RA, Grant PJ. The influence of type 2 diabetes on fibrin structure and function. Diabetologia.2005;48(6):1198-1206.
[7] Weisel JW, Litvinov RI. Mechanisms of fibrin polymerization and clinical implications. Blood. 2013;121(10):1712-1719.
[8] Mosesson MW, Siebenlist KR, Meh DA. The structure and biological features of fibrinogen and fibrin. Ann N Y Acad Sci. 2001;936:11-30.
[9] Levi M, de Jonge E, van der Poll T. Plasma and cellular markers of inflammation in patients with sepsis. J Thromb Haemost. 2003;1(4):790-794.
[10] Lowe GD, Rumley A, Mackie IJ. Plasma fibrinogen. Ann Clin Biochem. 2004;41(Pt 6):430-440.
[11] Dempfle CE, Wurst M, Smolinski M, Lorenz S, Wenzel E. Impact of fibrinogen concentration in severely ill patients on mechanical properties of whole blood clots. Blood Coagul Fibrinolysis. 2008;19(8):765-770.

If You Found This Test Helpful, You Might Also Like..

bottom of page