top of page

Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

lab-scientists-blood-urine-test-analysis

Fractional Exhaled Nitric Oxide

adult-man-testing-breathing-function-by-spirometry

FENO

Description

"Fractional Exhaled Nitric Oxide (FeNO)" test measures nitric oxide levels in your breath to assess airway inflammation, often related to asthma. It’s commonly used to confirm asthma diagnoses, evaluate inflammation levels, or fine-tune anti-inflammatory treatments. During the test, you exhale slowly into a device that analyzes nitric oxide concentration. Higher levels usually point to allergic or eosinophilic asthma. Results help doctors tailor medications and monitor control over time, supporting more effective respiratory care.

"Fractional Exhaled Nitric Oxide (FeNO)" test measures nitric oxide levels in your breath to assess airway inflammation, often related to asthma. It’s commonly used to confirm asthma diagnoses, evaluate inflammation levels, or fine-tune anti-inflammatory treatments. During the test, you exhale slowly into a device that analyzes nitric oxide concentration. Higher levels usually point to allergic or eosinophilic asthma. Results help doctors tailor medications and monitor control over time, supporting more effective respiratory care.

Test Category

Lung Function

Procedure

Non-Invasive

Sample Type

Breath

Units

Parts Per Billion

Procedure Category

Measure

Test Group

Complete Pulmonary Function Group

Test Group Description

Complete Pulmonary Function Group: Comprehensive evaluations of respiratory function offer detailed insights into lung function, airway inflammation, and structural abnormalities, facilitating the precise diagnosis and management of pulmonary conditions.

Optimal Range

For Adults:

  • Conventional Unit: Not Available

  • SI Unit: Not Applicable


For Children:

  • Conventional Unit: Not Available

  • SI Unit: Not Applicable

Normal Range

For Adults:

  • Conventional Unit: <25.00 ppb

  • SI Unit: Not Applicable


For Children:

  • Conventional Unit: <20.00 ppb

  • SI Unit: Not Applicable

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Asthma (Airway inflammation leading to increased nitric oxide production)

  • Chronic obstructive pulmonary disease (Chronic inflammation of the airways)

  • Psoriasis (Skin inflammation leading to increased systemic inflammation)

  • Pulmonary arterial hypertension (Increased pressure in the pulmonary arteries)

  • Respiratory tract inflammation (General inflammation of the respiratory tract)

Key Reasons For Testing

  • Airway Inflammation Marker: Fractional exhaled nitric oxide (FeNO) measures airway inflammation via exhaled breath.

  • Assessment of Inflammation: Elevated FeNO levels indicate asthma, allergic rhinitis, or eosinophilic bronchitis.

  • Asthma Diagnosis & Monitoring: Provides objective data for asthma diagnosis and treatment evaluation.

  • Eosinophilic Phenotype Identification: Pinpoints eosinophilic airway infla...

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Miskoff JA, Dewan A, Chaudhri M. Fractional Exhaled Nitric Oxide Testing: Diagnostic Utility in Asthma, Chronic Obstructive Pulmonary Disease, or Asthma-chronic Obstructive Pulmonary Disease Overlap Syndrome. Cureus.2019;11(6).

[2] Dweik RA, Boggs PB, Erzurum SC, et al. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FeNO) for clinical applications. Am J Respir Crit Care Med. 2011;184(5):602-615.

[3] Barnes PJ, Liew FY. Nitric oxide and asthmatic inflammation. Immunol Today. 1995;16(3):128-130.

[4] Smith AD, Cowan JO, Filsell S, et al. Diagnosing asthma: comparisons between exhaled nitric oxide measurements and conventional tests. Am J Respir Crit Care Med. 2004;169(4):473-478.

[5] Dupont LJ, Demedts MG, Verleden GM. Prospective evaluation of the validity of exhaled nitric oxide for the diagnosis of asthma. Chest. 2003;123(3):751-756.

[6] Taylor DR, Pijnenburg MW, Smith AD, de Jongste JC. Exhaled nitric oxide measurements: clinical application and interpretation. Thorax. 2006;61(9):817-827.

[7] Henriksen AH, Rønnevig JR, Botten G, et al. Combined use of exhaled nitric oxide and airway hyperresponsiveness in characterizing asthma in young adults. Am J Respir Crit Care Med. 1999;159(6):1531-1536.

[8] Malinovschi A, Janson C, Holm L, et al. Exhaled nitric oxide as a marker of airway inflammation in subjects with atopy and asthma. Clin Physiol Funct Imaging. 2006;26(1):44-49.

[9] Gelb AF, Flynn Taylor C, Shinar CM, et al. Role of spirometry and exhaled nitric oxide to predict exacerbations in treated asthmatics. Chest. 2006;129(6):1492-1499.

[10] Guo FH, Comhair SA, Zheng S, et al. Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis. J Immunol. 2000;164(11):5970-5980.

[11] Silkoff PE, McClean PA, Slutsky AS, et al. Exhaled nitric oxide: a test for inflammation in asthma. Am J Respir Crit Care Med. 1997;155(6):1823-1826.

[12] Ricciardolo FL, Gaston B, Hunt J. Acid stress in the pathology of asthma. J Allergy Clin Immunol. 2004;113(4):610-619.

[13] Baraldi E, de Jongste JC. Measurement of exhaled nitric oxide in children, 2001. Eur Respir J. 2002;20(1):223-237.

If You Found This Test Helpful, You Might Also Like..

bottom of page