Globulin
GLOB
Description
"Globulin" test measures key proteins in your blood that support immune function, nutrient transport, and liver health. Doctors often recommend it when symptoms like fatigue, swelling, or weight changes need further investigation. Low levels may indicate liver dysfunction or protein loss, while high levels can suggest chronic inflammation, infection, or certain cancers. This test is part of a broader metabolic or liver panel. Results help guide diagnosis and shape treatment plans for immune, nutritional, or hepatic concerns.
Test Category
Proteins
Procedure
Invasive
Sample Type
Blood – Serum
Units
Grams Per Deciliter | Grams Per Liter
Procedure Category
Blood Draw
Test Group
Complete Liver Group, Male Health Group, Female Health Group, Complete Metabolic Group, Gastrointestinal System Group, Immune System Group, Proteins Group
Test Group Description
Complete Liver Group: A thorough array of tests aimed at assessing liver function, providing detailed insights into hepatic health and related conditions. Complete Metabolic Group: A comprehensive suite of tests designed to evaluate metabolic function, offering detailed insights into various aspects of metabolism and associated health conditions. Female Health Group: A comprehensive array of tests provides insights into various aspects of female health and wellness, aiding in the evaluation and management of overall health for females. Gastrointestinal Health Group: This group assesses different facets of gastrointestinal function and health, providing insights into digestive well-being and related conditions. Immune System Group: By evaluating various aspects of immune system function and health, this group offers insights into immune responses and related health considerations. Male Health Group: A comprehensive array of tests provides insights into various aspects of male health and wellness, aiding in the evaluation and management of overall health for men. Proteins Group: This group comprises tests assessing various aspects of protein levels and function, providing valuable insights into overall protein status and associated health considerations.
Optimal Range
For All Individuals:
Conventional Unit: 2.4–2.8 g/dL
SI Unit: 24–28 g/L
Normal Range
For All Individuals:
Conventional Unit: 2.0–3.5 g/dL
SI Unit: 20–35 g/L
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Dehydration
Hemolytic anaemia (Breakdown of red blood cells)
Hodgkin lymphoma (Type of lymphatic system cancer)
Hodgkin's disease (Type of lymphatic system cancer)
Infections
Inflammation
Leukemia (Cancer of the blood-forming tissues)
- ...
Key Reasons For Testing
Liver Health: Globulin testing evaluates liver function, detecting conditions like hepatitis, cirrhosis, or fatty liver disease.
Kidney Function: Altered globulin levels indicate kidney issues such as nephrotic syndrome or glomerulonephritis.
Immune Function: Tests assess immune health, aiding diagnosis of autoimmune diseases or immunodeficiencies.
Inflammation Marker: Elevated levels suggest inflammation ...
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
[1] Burtis CA, Ashwood ER, Bruns DE, eds. Tietz Fundamentals of Clinical Chemistry. 6th ed. St. Louis, MO: Elsevier Saunders; 2008:322-326.
[2] Keren DF, Humphrey RL. Clinical significance of serum protein electrophoresis and immunofixation electrophoresis. Clin Lab Med. 1997;17(3):699-720.
[3] Bossuyt X. Clinical performance characteristics of a lab test. Clin Chim Acta. 2009;411(19-20):1611-1620.
[4] Wu AHB, ed. Tietz Clinical Guide to Laboratory Tests. 4th ed. St Louis, MO: Elsevier Saunders; 2006.
[5] Rifai N, Horvath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. St Louis, MO: Elsevier; 2018,33.
[6] Radin NS. The nature and function of serum globulin fractions. J Clin Invest. 1954;33(10):1473-1478.
[7] Ezeh NC, Bhandari M, Laronga C. Serum protein electrophoresis in cancer diagnosis. Clin Chim Acta. 2005;358(1-2):104-108.
[8] Kaneko JJ, Harvey JW, Bruss ML. Clinical Biochemistry of Domestic Animals. 6th ed. Academic Press; 2008,10.
[9] Harding C, Zhao H, Berend KR. Serum globulin and health monitoring. Am J Clin Pathol. 2003;120(5):768-773.
[10] Rosenthal NS, Jennings CD. Advances in serum protein electrophoresis. Am J Clin Pathol. 1996;106(1):2-5.
[11] McPherson RA, Pincus MR, eds. Henry’s Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. St Louis, MO: Elsevier; 2017,34.
[12] Hashash JG, Koutroumpakis F, Anderson AM, et al. Elevated serum globulin fraction as a biomarker of multiyear disease severity in inflammatory bowel disease. Ann Gastroenterol. 2022;35(6):609-617.