Glucose-6-Phosphate Dehydrogenase
G6PD
Description
"Glucose-6-Phosphate Dehydrogenase" (G6PD) test measures the activity of the G6PD enzyme, which protects red blood cells from damage. It’s commonly used to diagnose G6PD deficiency, a genetic condition that can trigger anemia after certain medications, infections, or foods. A blood sample is tested to check enzyme function. Low levels may indicate deficiency, especially if symptoms like fatigue, jaundice, or dark urine occur. Results help doctors confirm the condition and recommend steps to avoid potential triggers.
Test Category
Enzymes
Procedure
Invasive
Sample Type
Blood – Serum
Units
Units Per Gram Hemoglobin
Procedure Category
Blood Draw
Test Group
Enzyme Group
Test Group Description
Enzyme Group: Evaluates enzyme levels and activity, offering insights into enzymatic function and related health conditions.
Optimal Range
For All Individuals:
Conventional Unit: 11.0–15.0 U/g Hb
SI Unit: Not Applicable
Normal Range
For All Individuals:
Conventional Unit: 8.6–18.6 U/g Hb
SI Unit: Not Applicable
Results That Differ From The Norm (Direct and Indirect Causes)
Abnormal results may indicate:
Chemical (naphthalene) exposure
Favism (Reaction to eating fava beans)
G6PD deficiency (Genetic deficiency of glucose-6-phosphate dehydrogenase)
Infections (Infectious diseases affecting G6PD levels)
Medication (such as antimalarial drugs and sulfa drugs)
Oxidative stress (Excessive oxidative damage to cells)
Key Reasons For Testing
Diagnosis of G6PD Deficiency: Identifies low levels of the G6PD enzyme, aiding in diagnosing hemolytic anemia.
Assessment of Hemolytic Risk: Evaluates risks of anemia from triggers like medications, foods, or infections.
Medication Safety Guidance: Ensures safe prescribing by identifying drugs to avoid in G6PD deficiency.
Preoperative Screening: Detects risks of hemolytic complications during surgery, guiding care.
Newborn Screening: Identifies G6PD deficiency early to prevent crises.
Genetic Counseling: Provides information for family planning and inheritance risks.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
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