top of page

Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

lab-scientists-blood-urine-test-analysis

International Normalized Ratio

different-type-serum-containing-blood-samples

INR

Description

"International Normalized Ratio" (INR) test measures how long it takes your blood to clot, especially when you’re on anticoagulant medication like warfarin. Doctors use this test to monitor treatment effectiveness and adjust dosages to prevent clotting or bleeding complications. A higher INR means slower clotting, while a lower INR suggests quicker clot formation. It’s particularly important for those with conditions like atrial fibrillation or artificial heart valves. Regular INR testing helps ensure balanced clotting and reduces health risks.

"International Normalized Ratio" (INR) test measures how long it takes your blood to clot, especially when you’re on anticoagulant medication like warfarin. Doctors use this test to monitor treatment effectiveness and adjust dosages to prevent clotting or bleeding complications. A higher INR means slower clotting, while a lower INR suggests quicker clot formation. It’s particularly important for those with conditions like atrial fibrillation or artificial heart valves. Regular INR testing helps ensure balanced clotting and reduces health risks.

Category

Clotting Factors

Procedure

Invasive

Sample Type

Blood – Serum

Units

Ratio

Procedure Category

Blood Draw

Test Group

Gallbladder Group, Complete Liver Group, Coagulation Group

Test Group Description

Coagulation Group: These targeted tests are designed to assess clotting factors and coagulation pathways, offering valuable insights into hemostasis and thrombotic disorders. Complete Liver Group: A thorough array of tests aimed at assessing liver function, providing detailed insights into hepatic health and related conditions. Gallbladder Group: This group of tests evaluates gallbladder function and health, providing insights into digestive well-being and related conditions.

Optimal Range

For All Individuals:

  • Conventional Unit: Not Applicable

  • SI Unit: Not Applicable


For Individuals on Warfarin Therapy:

  • Conventional Unit: Not Applicable

  • SI Unit: Not Applicable

Normal Range

For All Individuals:

  • Conventional Unit: 0.9–1.2

  • SI Unit: Not Applicable


For Individuals on Warfarin Therapy:

  • Conventional Unit: 2.0–3.0

  • SI Unit: Not Applicable

Results That Differ From The Norm (Direct and Indirect Causes)

Abnormal results may indicate:


  • Anticoagulant reversal (Administration of agents to counteract the effects of anticoagulants)

  • Antiphospholipid syndrome (Autoimmune disorder predisposing to blood clot formation)

  • Celiac disease (Autoimmune disorder affecting the small intestine)

  • Deep vein thrombosis (Blood clot formation in deep veins)

  • Disseminated intravascular coagulati...

Key Reasons For Testing

  • Anticoagulation Monitoring: Ensures therapeutic INR range for patients on warfarin, minimizing bleeding or clotting risks.

  • Liver Function Assessment: Reflects clotting factor synthesis impairment, aiding in liver disease severity evaluation.

  • Surgical Risk Assessment: Guides bleeding risk evaluation before surgery, supporting safe perioperative management.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Tripodi A, Caldwell SH, Hoffman M, Trotter JF, Sanyal AJ. The prothrombin time test as a measure of bleeding risk and prognosis in liver disease. Clin Liver Dis. 2009;13(1):19-34.
[2] Baglin T, Keeling D, Kitchen S. Effects on the International Normalized Ratio of changes in the International Sensitivity Index of thromboplastin. J Thromb Haemost. 2004;2(5):736-741.
[3] Wittkowsky AK. Warfarin and the International Normalized Ratio: issues and implications. J Thromb Thrombolysis. 2001;12(2):137-143.
[4] Hirsh J, Fuster V, Ansell J, Halperin JL. American Heart Association/American College of Cardiology Foundation guide to warfarin therapy. Circulation. 2003;107(12):1692-1711.
[5] van den Besselaar AM. The International Normalized Ratio for oral anticoagulant therapy: local calibration of International Sensitivity Index for reference thromboplastins. Clin Chem Lab Med. 2005;43(5):430-434.
[6] Rose AJ, Berlowitz DR, Frayne SM, Hylek EM. Measuring quality of oral anticoagulation care: extending quality measurement to a new field. Jt Comm J Qual Patient Saf. 2009;35(3):146-155.
[7] Sconce E, Khan T, Mason J, Noble F, Wynne H, Kamali F. Patients with unstable control have a poorer dietary intake of vitamin K. Thromb Haemost. 2005;93(5):872-875.
[8] Van Veen JJ, Nokes TJ, Makris M. The management of thromboembolic risk in patients with atrial fibrillation: clinical practice and the role of thrombotic risk assessment models. Blood Coagul Fibrinolysis. 2011;22(7):554-559.
[9] Gulseth MP, Grice GR, Dager WE. Pharmacokinetics and pharmacodynamics of argatroban: effects of heart failure, liver disease, and renal dysfunction: a review of the literature. J Thromb Thrombolysis. 2008;25(1):30-39.
[10] Bajzar L, Fredenburgh JC, Nesheim ME. The activated protein C pathway: a role in controlling thrombin generation in the unstimulated state. Blood. 1996;88(3):816-824.
[11] White RH, McKittrick T, Hutchinson R, Twitchell J. Temporary discontinuation of warfarin therapy: changes in the International Normalized Ratio. Ann Intern Med. 1995;122(1):40-42.
[12] Wintzen AR, de Jonge H, Loeliger EA, Bots GT. The risk of intracerebral hemorrhage during oral anticoagulant treatment: a population study. Ann Neurol. 1984;16(5):553-558.
[13] Ansell J, Hirsh J, Hylek E, Jacobson A, Crowther M, Palareti G. Pharmacology and management of the vitamin K antagonists. Chest. 2008;133(6 Suppl):160S-198S.
[14] Keeling D, Baglin T, Tait C, et al. Guidelines on oral anticoagulation with warfarin. Br J Haematol. 2011;154(3):311-324.

If You Found This Test Helpful, You Might Also Like..

bottom of page