
Large High-Density Lipoprotein Particle Number

LHDL P
Description
"Large High-Density Lipoprotein (HDL) Particle Number" test measures how many large HDL particles are present in your blood, offering insight into your body’s ability to remove excess cholesterol. A higher count is generally linked to greater heart protection, while a low number may raise cardiovascular risk. Doctors use this test when standard lipid panels don’t provide enough detail. Results guide targeted strategies such as diet, exercise, or medication. Monitoring large HDL particles supports cholesterol balance and long-term heart health.
Test Category
Lipids, Proteins
Procedure
Invasive
Sample Type
Blood – Serum
Units
Micromoles Per Liter
Procedure Category
Blood Draw
Test Group
Complete Cardiovascular Group, Lipoprotein Fractionation Group
Test Group Description
Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments. Lipoprotein Fractionation Group: Analyzes lipoprotein fractions through NMR technology, providing detailed insights into lipid metabolism and cardiovascular health.
Optimal Range
For All Individuals:
Conventional Unit: >7.20 µmol/L
SI Unit: >7.20 µmol/L
Normal Range
For All Individuals:
Conventional Unit: >3.50 µmol/L
SI Unit: >3.50 µmol/L
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Alcoholism
Cholestasis (Impaired bile flow from the liver)
Estrogen replacement therapy (Supplemental estrogen hormone therapy)
Genetic factors (Inherited traits affecting lipid metabolism)
Healthy fat consumption
Medications (such as nicotinic acid or fibrates)
- ...
Key Reasons For Testing
Cardiovascular Risk Assessment: Large HDL particle numbers indicate reduced risks of heart disease and stroke.
Metabolic Health Evaluation: Reflects insulin sensitivity and improved glucose metabolism.
Dyslipidemia Subtype Identification: Detects specific subtypes with cardiovascular implications.
Evaluation of Treatment Efficacy: Tracks response to lipid-lowering therapies.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
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[2] Cromwell WC, Otvos JD. Heterogeneity of low-density lipoprotein particle number in patients with type 2 diabetes mellitus and low-density lipoprotein cholesterol <100 mg/dl. Am J Cardiol. 2006;98(12):1599-1602.
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