Monocyte Relative
MONO REL
Description
"Monocyte Relative" test calculates the percentage of monocytes within your total white blood cell count to assess immune function and inflammation. It’s often recommended when you're experiencing fatigue, unexplained swelling, or signs of chronic infection. Elevated monocyte percentages may point to inflammation, autoimmune conditions, or infection, while lower values could reflect immune suppression. Doctors use the results to guide further testing or treatment. Monitoring monocyte ratios over time helps support diagnosis and maintain immune system balance.
Category
Blood Cells
Procedure
Invasive
Sample Type
Blood – Whole Blood
Units
Percentage
Procedure Category
Blood Draw
Test Group
Hematology Group, Complete Prostate Group, Immune System Group, Blood Count Differentials Group
Test Group Description
Blood Count Differentials Group: This group comprises tests essential for evaluating the different types of blood cells, offering detailed insights into blood cell composition, and aiding in the diagnosis of various blood disorders. Complete Prostate Group: Extensive tests offering a comprehensive assessment of prostate health, providing detailed insights into prostate function and associated conditions. Immune System Group: By evaluating various aspects of immune system function and health, this group offers insights into immune responses and related health considerations. Hematology Group: Tests within this group focus on evaluating various aspects of blood health and function. These assessments provide insights into red blood cells, white blood cells, platelets, and other components of the blood.
Optimal Range
For All Individuals:
Conventional Unit: 4.00–7.00%
SI Unit: Not Applicable
Normal Range
For All Individuals:
Conventional Unit: 1.70–9.30%
SI Unit: Not Applicable
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Bacterial infections
Chronic kidney disease
Chronic stress
Crohn's disease (Chronic inflammatory bowel disease)
Fungal infections
Human immunodeficiency virus (Viral infection leading to chronic immune activation)
Medications (such as corticosteroids)
...
Key Reasons For Testing
Assessment of Immune Function: Reflects immune system activity in response to infections and inflammation.
Detection of Infections: Indicates bacterial infections through changes in relative monocyte levels.
Monitoring Inflammatory Conditions: Tracks elevated monocyte percentages in diseases like lupus and rheumatoid arthritis.
Evaluation of Autoimmune Diseases: Assesses immune dysregulation in conditions such as vasculitis.
Identification of Hematological Disorders: Detects abnormal monocyte percentages linked to leukemia and lymphoma.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
[1] Ziegler-Heitbrock L. The CD14+ CD16+ blood monocytes: their role in infection and inflammation. J Immunol. 2007;7(5):503-509.
[2] Fingerle G, Pforte A, Passlick B, Blumenstein M, Ströbel M, Ziegler-Heitbrock HW. The novel subset of CD14+/CD16+ blood monocytes is expanded in sepsis patients. Blood. 1993;82(10):3170-3176.
[3] Skrzeczyńska-Moncznik J, Bzowska M, Loseke S, Grage-Griebenow E, Zembala M, Pryjma J. Peripheral blood CD14high CD16+ monocytes are main producers of IL-10. Scand J Immunol. 2008;67(2):152-159.
[4] Wong KL, Tai JJ, Wong WC, Han H, Sem X, Yeap WH, et al. Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets. Blood. 2011;118(5).
[5] Zawada AM, Rogacev KS, Rotter B, et al. SuperSAGE evidence for CD14++ CD16+ monocytes as a third monocyte subset. Blood. 2011;118(12).
[6] Mukherjee R, Kanti Barman P, Thatoi PK, Tripathy R, Das BK. Emerging functional divergence of monocyte subsets in human diseases. Scand J Immunol. 2015;82(3):189-200.
[7] Rossol M, Kraus S, Pierer M, Baerwald C, Wagner U. The CD14bright CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes Th17 expansion. Arthritis Rheum. 2012;64(3):671-677.
[8] Ancuta P, Rao R, Moses A, et al. Fractalkine preferentially mediates arrest and migration of CD16+ monocytes. J Exp Med. 2003;197(12):1701-1707.
[9] van Furth R, Cohn ZA. The origin and kinetics of mononuclear phagocytes. J Exp Med. 1968;128(3):415-435.
[10] Shantsila E, Tapp LD, Wrigley BJ, et al. Monocyte subsets in coronary artery disease and their associations with markers of inflammation and fibrinolysis. Atherosclerosis. 2014;234(4):4-10.
[11] Tak T, Drylewicz J, Conemans L, et al. Circulatory and maturation kinetics of human monocyte subsets in vivo. Cell Rep. 2017;20(8):2183-2191.