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Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Platelet-to-Lymphocyte Ratio

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PLT / LYM

Description

"Platelet-to-Lymphocyte Ratio" test analyzes your platelet and lymphocyte levels to assess inflammation and immune system activity. It’s often used in evaluating cancer progression, cardiovascular risk, or autoimmune disease severity. A high ratio may signal active inflammation or stress, while a low ratio might reflect immune suppression. Doctors use this test to help interpret prognosis and refine care strategies. Tracking PLR levels over time helps monitor treatment response and guide long-term inflammation and immune system support.

"Platelet-to-Lymphocyte Ratio" test analyzes your platelet and lymphocyte levels to assess inflammation and immune system activity. It’s often used in evaluating cancer progression, cardiovascular risk, or autoimmune disease severity. A high ratio may signal active inflammation or stress, while a low ratio might reflect immune suppression. Doctors use this test to help interpret prognosis and refine care strategies. Tracking PLR levels over time helps monitor treatment response and guide long-term inflammation and immune system support.

Test Category

Blood Cells, Clotting Factors

Procedure

Invasive

Sample Type

Blood – Serum

Units

Ratio

Procedure Category

Blood Draw

Test Group

Hematology Group, Blood Count Supplementary Group, Basic Inflammation Group, Complete Inflammation Group

Test Group Description

Basic Inflammation Group: This set of tests helps evaluate the body's inflammatory response, providing valuable information for diagnosing and managing inflammatory conditions. Blood Count Supplementary Group: This group includes additional tests beyond the standard complete blood count, offering supplementary information to further characterize blood composition and provide comprehensive insights into hematologic health. Complete Inflammation Group: Extensive tests offer a comprehensive assessment of inflammatory markers, yielding detailed insights into inflammation levels and related health conditions. Hematology Group: Tests within this group focus on evaluating various aspects of blood health and function. These assessments provide insights into red blood cells, white blood cells, platelets, and other components of the blood.

Optimal Range

For All Individuals:

  • Conventional Unit: <150.0 R

  • SI Unit: Not Applicable

Normal Range

For All Individuals:

  • Conventional Unit: 100.00–300.00 R

  • SI Unit: Not Applicable

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Bacterial infections

  • Chronic kidney disease

  • Chronic liver disease

  • Chronic obstructive pulmonary disease (Long-term lung disease characterized by airflow obstruction)

  • Colorectal cancer (Cancerous growths in the colon or rectum)

  • Coronary artery disease (Narrowing or blockage of the coronary ...

Key Reasons For Testing

  • Inflammatory Marker: Reflects the balance between platelet activation and lymphocyte-mediated immune response.

  • Prognostic Indicator: Predicts outcomes in cancer, cardiovascular disorders, and infections.

  • Risk Stratification: Identifies high-risk patients in sepsis, cancer, and severe diseases.

  • Response to Therapy: Tracks treatment efficacy, with trends indicating disease control or progression.

  • Prognostic Value in Critical Illness: Assesses outcomes like ICU admission and mortality in critically ill patients.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Templeton AJ, Ace O, McNamara MG, et al. Prognostic role of platelet to lymphocyte ratio in solid tumors: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2014;23(7):1204-1212.

[2] Lee JS, Kim NY, Na SH, Youn YH, Shin CS. Reference values of neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio, platelet-lymphocyte ratio, and mean platelet volume in healthy adults in South Korea. Medicine (Baltimore). 2018;97(26).

[3] Kurtul A, Ornek E. Platelet to lymphocyte ratio in cardiovascular diseases: a systematic review. Angiology. 2019;70(9):802-818.

[4] Li W, Liu Z, Liu T, et al. Prognostic value of platelet-to-lymphocyte ratio in colorectal cancer: a systematic review and meta-analysis. Medicine (Baltimore). 2019;98(28).

[5] Erre GL, Paliogiannis P, Castagna F, et al. Meta-analysis of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio in rheumatoid arthritis. Eur J Clin Invest. 2019;49(1).

[6] Faria SS, Fernandes PC Jr, Silva MJ, et al. The neutrophil-to-lymphocyte ratio: a narrative review. Ecancermedicalscience. 2016;10:702.

[7] Krenn-Pilko S, Langsenlehner U, Thurner EM, et al. The elevated preoperative platelet-to-lymphocyte ratio predicts poor prognosis in breast cancer patients. Br J Cancer. 2014;110(10):2524-2530.

[8] Smith RA, Ghaneh P, Sutton R, et al. Prognostic factors in pancreatic cancer. HPB (Oxford). 2009;11(1):24-30.

[9] Smith RA, Bosonnet L, Raraty M, et al. Preoperative platelet-lymphocyte ratio is an independent significant prognostic marker in resected pancreatic ductal adenocarcinoma. Am J Surg. 2009;197(4):466-472.

[10] Smith RA, Bosonnet L, Ghaneh P, et al. The platelet-lymphocyte ratio and CA19-9 predict survival in patients with pancreatic cancer. Br J Surg. 2008;95(6):711-717.

[11] Azab B, Shah N, Radbel J, et al. Pretreatment neutrophil/lymphocyte ratio is superior to platelet/lymphocyte ratio as a predictor of long-term mortality in breast cancer patients. Med Oncol. 2013;30(1):432.

[12] Mohamed K, Algohary A, Saleh A, et al. Platelet-to-lymphocyte ratio as a predictive biomarker in cardiovascular and oncological disorders: a narrative review. J Hematol Oncol. 2021;14(1):143.

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