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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Quantitative Insulin Sensitivity Check Index

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QUICKI

Description

"Quantitative Insulin Sensitivity Check Index" (QUICKI) test assesses how efficiently your body responds to insulin by analyzing fasting glucose and insulin levels. Doctors use this test to evaluate risk for insulin resistance, metabolic syndrome, or type 2 diabetes. A lower QUICKI score suggests reduced insulin sensitivity and higher metabolic risk. Results guide early interventions like diet changes, physical activity, or medication. Ongoing monitoring supports proactive care and helps maintain long-term metabolic and blood sugar health.

"Quantitative Insulin Sensitivity Check Index" (QUICKI) test assesses how efficiently your body responds to insulin by analyzing fasting glucose and insulin levels. Doctors use this test to evaluate risk for insulin resistance, metabolic syndrome, or type 2 diabetes. A lower QUICKI score suggests reduced insulin sensitivity and higher metabolic risk. Results guide early interventions like diet changes, physical activity, or medication. Ongoing monitoring supports proactive care and helps maintain long-term metabolic and blood sugar health.

Category

Hormones

Procedure

Invasive

Sample Type

Blood – Serum

Units

Ratio

Procedure Category

Blood Draw

Test Group

Complete Blood Sugar Group

Test Group Description

Complete Blood Sugar Group: This expanded group includes a more comprehensive set of tests, offering a thorough evaluation of diverse facets of blood sugar levels for a more detailed understanding of metabolic health.

Optimal Range

For All Individuals:

  • Conventional Unit: 0.45–5.00 R

  • SI Unit: Not Applicable

Normal Range

For All Individuals:

  • Conventional Unit: 0.34–5.00 R

  • SI Unit: Not Applicable

Results That Differ From The Norm (Direct and Indirect Causes)

Decreased levels may indicate:


  • Insulin Resistance (Reduced sensitivity to insulin)

  • Metabolic syndrome (Cluster of conditions including high blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels)

  • Polycystic Ovary Syndrome (A hormonal disorder common among women of reproductive age, often associated with insulin resistance)

  • Type 2 Diabetes (Metabolic disorder characterized by high blood sugar levels)

Key Reasons For Testing

  • Insulin Sensitivity Assessment: Provides a simple method to evaluate the body's response to insulin.

  • Diabetes Risk Prediction: Identifies reduced insulin sensitivity associated with a higher risk of type 2 diabetes.

  • Metabolic Syndrome Evaluation: Assesses insulin resistance as part of metabolic syndrome evaluation.

  • Monitoring Insulin-Sensitizing Therapies: Tracks changes in insulin sensitivity during treatments like lifestyle modifications or medications.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Katz A, Nambi SS, Mather K, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85(7):2402-2410.

[2] Hrebícek J, Janout V, Malincíková J, et al. Detection of insulin resistance by simple quantitative insulin sensitivity check index QUICKI for epidemiological assessment and prevention. J Clin Endocrinol Metab. 2002;87(1):144-147.

[3] Rabasa-Lhoret R, Bastard JP, Jan V, et al. Modified quantitative insulin sensitivity check index is better correlated to hyperinsulinemic glucose clamp than other fasting-based index of insulin sensitivity in different insulin-resistant states. J Clin Endocrinol Metab. 2003;88(10):4917-4923.

[4] Chen H, Sullivan G, Quon MJ. Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model. Diabetes. 2005;54(7):1914-1925.

[5] Muniyappa R, Lee S, Chen H, et al. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab.2008;294(1).

[6] Perseghin G, Caumo A, Caloni M, et al. Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in nonobese individuals. J Clin Endocrinol Metab. 2001;86(10):4776-4781.

[7] Quon MJ. Limitations of the fasting glucose to insulin ratio as an index of insulin sensitivity. J Clin Endocrinol Metab. 2001;86(10):4615-4617.

[8] Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 1999;22(9):1462-1470.

[9] Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care.2004;27(6):1487-1495.

[10] McAuley KA, Williams SM, Mann JI, et al. Diagnosing insulin resistance in the general population. Diabetes Care. 2001;24(3):460-464.

[11] Bonora E, Targher G, Alberiche M, et al. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care. 2000;23(1):57-63.

[12] Quon MJ, Chen H, Zarnowski MJ, et al. A simple insulin sensitivity index based on the combined fasting glucose and insulin concentrations: the empirical derivation and clinical validation. Diabetes Care. 2003;26(3):725-731.

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