top of page

Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

lab-scientists-blood-urine-test-analysis

Rapid Plasma Reagin

extraction-plasma-from-blood

RPR

Description

"Rapid Plasma Reagin" (RPR) test screens for syphilis by detecting antibodies that form in response to the infection. It’s commonly used during STI screenings, pregnancy care, or when symptoms like sores, rashes, or neurological changes appear. A positive result indicates possible syphilis exposure and is followed by confirmatory testing. Doctors use RPR to diagnose, monitor treatment success, or detect reinfection. Early detection supports effective care, reduces transmission risk, and helps manage long-term complications of untreated syphilis.

"Rapid Plasma Reagin" (RPR) test screens for syphilis by detecting antibodies that form in response to the infection. It’s commonly used during STI screenings, pregnancy care, or when symptoms like sores, rashes, or neurological changes appear. A positive result indicates possible syphilis exposure and is followed by confirmatory testing. Doctors use RPR to diagnose, monitor treatment success, or detect reinfection. Early detection supports effective care, reduces transmission risk, and helps manage long-term complications of untreated syphilis.

Category

Antibodies

Procedure

Invasive

Sample Type

Blood – Plasma

Units

Not Applicable

Procedure Category

Blood Draw

Test Group

Chronic Illness Group

Test Group Description

Chronic Illness Group: This group encompasses a range of tests specifically tailored to assess markers associated with chronic health conditions, providing comprehensive insights into the management and monitoring of chronic illnesses.

Optimal Range

For All Individuals:

  • Result: Negative: No abnormalities detected.

Normal Range

For All Individuals:

  • Result: Negative: No abnormalities detected.

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Antiphospholipid syndrome (Autoimmune disorder affecting blood clotting)

  • Congenital syphilis (Syphilis infection transmitted from mother to baby during childbirth)

  • Human immunodeficiency virus (Viral infection that attacks the body's immune system)

  • Pinta (Bacterial infection caused by Treponema carateum)

  • Pregnancy

    ...

Key Reasons For Testing

  • Syphilis Screening: Detects antibodies to diagnose syphilis and enable early treatment.

  • Monitoring Syphilis Treatment Response: Tracks changes in antibody titers to assess treatment effectiveness.

  • Prenatal Screening: Identifies and treats syphilis in pregnant individuals to prevent congenital transmission.

  • Contact Tracing and Disease Control: Facilitates the identification and treatment of exposed individuals to prevent further transmission.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Larsen SA, Pope V, Johnson RE, Kennedy EJ Jr. A Manual of Tests for Syphilis. Washington, DC: American Public Health Association; 1998.

[2] Ratnam S. The laboratory diagnosis of syphilis. Can J Infect Dis Med Microbiol. 2005;16(1):45-51.

[3] Workowski KA, Bachmann LH, Chan PA, et al. Sexually transmitted infections treatment guidelines, 2021. MMWR Recomm Rep. 2021;70(4):1-187.

[4] Henao-Martínez AF, Johnson SC. Diagnostic tests for syphilis: new tests and new algorithms. Neurol Clin Pract. 2014;4(2):114-122.

[5] Centers for Disease Control and Prevention. Syphilis testing algorithms using treponemal tests for initial screening—four laboratories, New York City, 2005–2006. MMWR Morb Mortal Wkly Rep.2008;57(32):872-875.

[6] Pope V, Norris SJ, Johnson RE. Treponema pallidum: methods of identification and diagnosis of syphilis. Clin Microbiol Rev. 1999;12(1):21-39.

[7] Hook EW 3rd, Marra CM. Acquired syphilis in adults. N Engl J Med. 1992;326(16):1060-1069.

[8] Ghanem KG, Ram S, Rice PA. The modern epidemic of syphilis. N Engl J Med. 2020;382(9):845-854.

[9] Castro AR, Jost H, Cruz AR, et al. Treponema pallidum polymerase chain reaction using whole blood and blood fractions: implications for syphilis diagnosis. J Clin Microbiol. 2007;45(7):2522-2526.

[10] Lafond RE, Lukehart SA. Biological basis for syphilis. Clin Microbiol Rev. 2006;19(1):29-49.

[11] Schöfer H. Syphilis in HIV infection: an update. Dermatol Ther (Heidelb). 2010;20(2):69-76.

[12] Lukehart SA, Hook EW 3rd. Syphilis: a modern pandemic. Curr Opin Infect Dis. 2008;21(2):101-107.

[13] Singh AE, Romanowski B. Syphilis: review with emphasis on clinical, epidemiologic, and some biologic features. Clin Microbiol Rev. 1999;12(2):187-209.

[14] Augenbraun M, Rolfs RT, Johnson R. The serological diagnosis of syphilis in HIV-infected patients. Ann Intern Med. 1992;117(2):101-107.

[15] Fiumara NJ. The benign late manifestations of syphilis: review with a report of 76 cases. Medicine (Baltimore). 1974;53(1):1-25.

If You Found This Test Helpful, You Might Also Like..

bottom of page