
Rapid Urease Test

RUT
Description
"Rapid Urease Test" (RUT) detects Helicobacter pylori by identifying urease activity in a stomach lining sample collected during endoscopy. Doctors recommend it when symptoms like stomach pain, nausea, or unexplained weight loss suggest ulcers or chronic gastritis. A color change in the test medium confirms H. pylori presence. Results help guide treatment with antibiotics and acid-reducing medications. RUT supports early diagnosis and helps prevent long-term complications linked to untreated gastrointestinal infections.
Category
Microbes
Procedure
Invasive
Sample Type
Fluid
Units
Not Applicable
Procedure Category
Insert, Extract
Test Group
Microbial Assessment Group, Infection Group
Test Group Description
Microbial Assessment Group: Tests in this group analyze microbial presence and activity in various samples, offering insights into microbial populations and their impact on health. They help identify specific microorganisms, assess microbial diversity, and evaluate microbial functions in different environments. Infection Group: Tests within this group detect markers indicative of various infections, aiding in the diagnosis and management of infectious diseases.
Optimal Range
For All Individuals:
Result: Negative: No abnormalities detected.
Normal Range
For All Individuals:
Result: Negative: No abnormalities detected.
Results That Differ From The Norm (Direct and Indirect Causes)
Abnormal results may indicate:
Duodenitis (Inflammation of the duodenum)
Gastric cancer (Malignant tumor of the stomach)
Gastritis (Inflammation of the stomach lining)
Gastroenteritis (Inflammation of the gastrointestinal tract, often due to viral or bacterial infections)
Helicobacter pylori infection (Bacterial infection of the stomach)
Mucosa-associated lymphoid tissue lymphoma (Type of lymphoma originating in mucosal tissue)
Peptic ulcers (Sores in the lining of the stomach or duodenum)
Zollinger-Ellison syndrome (Rare disorder characterized by gastrin-secreting tumors)
Key Reasons For Testing
H. pylori Detection: Identifies Helicobacter pylori in gastric biopsies to diagnose related gastritis, peptic ulcers, and malignancies.
Diagnostic Accuracy: Provides rapid and reliable results, ensuring timely diagnosis and treatment.
Treatment Monitoring: Detects persistent infection post-treatment to guide further management and prevent recurrence.
Management of Dyspeptic Symptoms: Helps identify H. pylori-associated gastritis for targeted therapy and symptom relief.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
[1] Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;1(8390):1311-1315.
[2] Graham DY, Klein PD. Accurate diagnosis of Helicobacter pylori: urease tests. Gastroenterology.2000;118(Suppl 1).
[3] Cutler AF, Havstad S, Ma CK, et al. Accuracy of invasive and noninvasive tests to diagnose Helicobacter pylori infection. Gastroenterology. 1995;109(5):136-141.
[4] Leodolter A, Kulig M, Brasch H, et al. Diagnostic accuracy of the rapid urease test for Helicobacter pylori in patients on acid-suppressive therapy. Am J Gastroenterol. 2003;98(1):79-85.
[5] Gisbert JP, de la Morena F, Abraira V. Accuracy of the rapid urease test for the diagnosis of Helicobacter pylori infection in patients with bleeding peptic ulcer: systematic review and meta-analysis. Dig Liver Dis. 2006;38(7):473-481.
[6] Gatta L, Ricci C, Tampieri A, et al. Accuracy of breath tests using low doses of C-labeled urea to diagnose Helicobacter pylori infection. Gastroenterology. 2003;125(6):1724-1731.
[7] Malfertheiner P, Megraud F, O'Morain CA, et al. Management of Helicobacter pylori infection—the Maastricht IV/Florence Consensus Report. Gut. 2012;61(5):646-664.
[8] Vakil N, Megraud F. Eradication therapy for Helicobacter pylori. Gastroenterology.2007;133(6):1867-1880.
[9] Vaira D, Holton J, Menegatti M, et al. Review article: invasive and non-invasive tests for Helicobacter pylori infection. Aliment Pharmacol Ther. 2000;14(Suppl 3):13-22.
[10] Thijs JC, van Zwet AA, Thijs WJ, et al. Diagnostic tests for Helicobacter pylori: a review. Eur J Gastroenterol Hepatol. 1996;8(6):501-507.
[11] Gisbert JP, Pajares JM. Diagnosis of Helicobacter pylori infection by stool antigen determination: a systematic review. Am J Gastroenterol. 2001;96(10):2829-2838.
[12] Laine L, Estrada R, Trujillo M, et al. Effect of proton-pump inhibitor therapy on diagnostic testing for Helicobacter pylori. Ann Intern Med. 1998;129(7):547-550.
[13] Moayyedi P, Axon AT, Feltbower R, et al. Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection. Int J Epidemiol. 2002;31(3):624-631.