
Dry Eyes

Description
This page has 34 references
"Dry Eyes" is a condition where the eyes fail to produce enough tears or retain adequate moisture, leading to discomfort and irritation. Triggers include prolonged screen time, aging, contact lens use, and environmental factors like dry air, wind, or smoke. Common symptoms include burning, stinging, redness, or blurry vision. Increasing hydration, boosting omega-3 intake, and using artificial tears can ease discomfort. Regular breaks from screens and shielding eyes from irritants help maintain long-term comfort and visual health.
Symptoms & Signs
Body System
Eyes and Vision
Causes
Aging, Weather Conditions, Air-Conditioning, Eye Injury, Medications, Laser Eye Surgery
Things To Do
If you are experiencing eye dryness, try the following:
consuming a whole-foods-based diet rich in omega-3 fatty acids and anti-inflammatory compounds.
applying a warm compress to your eyes three times a day.
drinking enough quality water.
optimizing the indoor humidity levels.
ventilating indoor spaces.
using air purifiers and humidifiers when necessary.
giving your eyes a rest from the screens and flashing lights.
blinking, which helps restore natural moisture.
using eye-moisturizing drops.
Furthermore, make sure to:
get enough quality sleep.
Wear sunglasses if the weather conditions outside cause your eyes to feel dry.
exercise regularily. Physical activity can increase tear secretion.
Things To Avoid
For eye dryness, avoid these practices:
drinking alcohol, coffee, and caffeinated beverages that extract moisture from the body.
staying too long in air-conditioned spaces.
wearing contact lenses for extended periods of time.
spending too much time in front of the computer, tablet, smartphone, or TV.
eating processed and fast foods.
wearing eye makeup.
Furthermore, avoid:
sleeping too little.
stress.
smoking.
Supplements
Direct Support
(Most Helpful → Least Helpful)
These supplements directly affect dry eyes by supporting tear production, reducing ocular surface inflammation, or improving lubrication of the eye.
Omega 3: Omega-3 improves the oil layer of the tear film, enhancing tear stability and reducing symptoms of dry eyes, such as irritation and discomfort.
Vitamin A: Vitamin A is crucial for maintaining the eye's surface tissues, preventing dryness and irritation. Adequate intake helps maintain moisture and promotes long-term eye health.
Vitamin D: Vitamin D supports tear production and reduces inflammation in the eyes, helping maintain moisture and reduce the risk of dry eye symptoms.
Zinc: Zinc supports the tear film structure, promoting tear stability and reducing dryness in the eyes. Supplementing zinc can alleviate dry eye symptoms by improving moisture retention.
Vitamin C: Vitamin C enhances tear production, supporting moisture levels in the eyes and alleviating discomfort caused by dryness, helping maintain overall eye health.
Carnitine: Carnitine protects ocular surface cells by reducing oxidative stress and osmotic imbalance, helping to relieve dryness and irritation.
Asthaxanthin Extract: Astaxanthin possesses strong anti-inflammatory and antioxidant properties, promoting tear film stability and hydrating the ocular surface, which helps reduce irritation, burning, and dryness.
Indirect Support
(Most Helpful → Least Helpful)
These supplements do not target dry eyes directly but may support immune balance, reduce oxidative stress, or improve skin and mucosal hydration.
No replicated and convincing research studies are available, and there is no anecdotal evidence supporting the effectiveness of this method.
Natural Compounds
These natural compounds may help alleviate dry eyes by improving tear film stability, supporting mucosal integrity, or easing eye surface discomfort.
Hyaluronic Acid: Hyaluronic acid improves tear film stability by increasing water retention, reducing evaporation, and maintaining hydration on the eye surface, providing relief from dry eye symptoms.
Manuka Honey: Manuka honey, applied topically, provides antimicrobial protection and promotes tear film stability, reducing symptoms of dry eye.
Plant Extracts
Direct Support
(Most Helpful → Least Helpful)
These plant extracts directly support relief from dry eyes by enhancing moisture retention, calming eye surface irritation, or reducing local inflammation.
Borage Oil: Borage oil contains gamma-linolenic acid (GLA), which stimulates tear production and helps maintain well-lubricated eyes, offering relief from dryness.
Evening Primrose Oil: Evening primrose oil is rich in gamma-linolenic acid (GLA), promoting tear production and maintaining eye lubrication, helping alleviate dry eye discomfort.
Indirect Support
(Most Helpful → Least Helpful)
These extracts do not act directly on dry eyes but may support overall eye health, reduce systemic inflammation, or assist with hydration and tissue repair.
No replicated and convincing research studies are available, and there is no anecdotal evidence supporting the effectiveness of this method.
Alternative Treatments
These alternative therapies support ocular hydration, reduce surface irritation, and promote tear stability in individuals experiencing dry eyes.
Warm Compress Therapy: Warm compresses improve meibomian gland function, enhancing lipid secretion and stabilizing the tear film to relieve dry eye discomfort.
Functional Lab Tests You May Wish to Explore
Books Worth Considering for Deeper Insight
Currently, no high-quality books meeting our functional, integrative, and natural healing standards are available for this condition. As soon as trusted resources are published, we will review and feature them here.
Podcasts That Offer Valuable Perspectives
Currently, no high-quality books meeting our functional, integrative, and natural healing standards are available for this condition. As soon as trusted resources are published, we will review and feature them here.
Educational Videos To Learn From
How Key Nutrients Support the Body
Antioxidants: Antioxidants protect cells from oxidative stress caused by free radicals, potentially reducing the risk of chronic diseases such as cancer and cardiovascular ailments. They safeguard DNA integrity, slow down aging processes, and support overall cellular health.
Fatty Acids: Fatty acids serve as energy sources, structural components of cell membranes, and precursors to signaling molecules. Essential fatty acids, like omega-3 and omega-6, play critical roles in brain function, cardiovascular health, and inflammation regulation.
Minerals: Minerals are essential for various physiological functions, including bone health, nerve transmission, and enzyme activity. They support overall health by ensuring proper cellular function and metabolic processes.
Other Nutrients: Other nutrients encompass a wide array of essential compounds crucial for various physiological functions. This category includes neurotransmitters and their precursors, which facilitate nerve signaling and are vital for central nervous system function. Additionally, naturally occurring structural components and biological detergents, such as phospholipids and bile salts, play critical roles in tissue repair, fat digestion, and overall bodily function. Phospholipids contribute to cell membrane integrity and fat emulsification, while bile salts are key to digesting and absorbing dietary fats. Hormones and their precursors regulate numerous physiological processes, including metabolism, growth, and reproduction. Furthermore, naturally occurring chemicals and metals play pivotal roles in enzymatic reactions, immune function, and overall health maintenance.
Vitamins: Vitamins are essential micronutrients that play diverse roles in supporting cellular processes, immune function, and overall health. They must be obtained through diet or supplementation to ensure proper bodily function.
Essential Nutrients Explained
References
[1] Huang JY, Yeh PT, Hou YC. A randomized, double-blind, placebo-controlled study of oral antioxidant supplement therapy in patients with dry eye syndrome. Clin Ophthalmol. 2016 May 9;10:813-20.
[2] Fogagnolo P, De Cilla' S, Alkabes M, Sabella P, Rossetti L. A Review of Topical and Systemic Vitamin Supplementation in Ocular Surface Diseases. Nutrients. 2021;13(6):1998. Published 2021 Jun 10.
[3] Fogagnolo P, De Cilla' S, Alkabes M, Sabella P, Rossetti L. A Review of Topical and Systemic Vitamin Supplementation in Ocular Surface Diseases. Nutrients. 2021;13(6):1998. Published 2021 Jun 10.
[4] Choy C, Benzie I, Cho P. Antioxidants in tears and plasma: Inter-relationships and effect of vitamin C supplementation. Curr Eye Res. 2003 Jul;27(1):55-60.
[5] Alanazi SA, El-Hiti GA, Al-Baloud AA, et al. Effects of short-term oral vitamin A supplementation on the ocular tear film in patients with dry eye. Clin Ophthalmol. 2019;13:599-604. Published 2019 Apr 10.
[6] Kobayashi TK, Tsubota K, Takamura E, Sawa M, Ohashi Y, Usui M. Effect of retinol palmitate as a treatment for dry eye: a cytological evaluation. Ophthalmologica. 1997;211(6):358-61.
[7] Kim EC, Choi JS, Joo CK. A comparison of vitamin a and cyclosporine a 0.05% eye drops for treatment of dry eye syndrome. Am J Ophthalmol. 2009 Feb;147(2):206-213.e3.
[8] Toshida H, Funaki T, Ono K, Tabuchi N, Watanabe S, Seki T, Otake H, Kato T, Ebihara N, Murakami A. Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial. Drug Des Devel Ther. 2017 Jun 23;11:1871-1879.
[9] Odaka A, Toshida H, Ohta T, Tabuchi N, Koike D, Suto C, Murakami A. Efficacy of retinol palmitate eye drops for dry eye in rabbits with lacrimal gland resection. Clin Ophthalmol. 2012;6:1585-93.
[10] Kokke KH, Morris JA, Lawrenson JG. Oral omega-6 essential fatty acid treatment in contact lens associated dry eye. Cont Lens Anterior Eye. 2008 Jun;31(3):141-6; quiz 170.
[11] Barabino S, Rolando M, Camicione P, Ravera G, Zanardi S, Giuffrida S, Calabria G. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. Cornea. 2003 Mar;22(2):97-101.
[12] Macrì A, Giuffrida S, Amico V, Iester M, Traverso CE. Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. Graefes Arch Clin Exp Ophthalmol. 2003 Jul;241(7):561-566.
[13] Ng A, Woods J, Jahn T, Jones LW, Sullivan Ritter J. Effect of a Novel Omega-3 and Omega-6 Fatty Acid Supplement on Dry Eye Disease: A 3-month Randomized Controlled Trial. Optom Vis Sci. 2022 Jan 1;99(1):67-75.
[14] Rashid S, Jin Y, Ecoiffier T, Barabino S, Schaumberg DA, Dana MR. Topical omega-3 and omega-6 fatty acids for treatment of dry eye. Arch Ophthalmol. 2008 Feb;126(2):219-25.
[15] Miljanović B, Trivedi KA, Dana MR, Gilbard JP, Buring JE, Schaumberg DA. Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J Clin Nutr. 2005 Oct;82(4):887-93.
[16] Al Mahmood AM, Al-Swailem SA. Essential fatty acids in the treatment of dry eye syndrome: A myth or reality? Saudi J Ophthalmol. 2014 Jul;28(3):195-7.
[17] Roncone M, Bartlett H, Eperjesi F. Essential fatty acids for dry eye: A review. Cont Lens Anterior Eye. 2010 Apr;33(2):49-54; quiz 100.
[18] Chinnery HR, Naranjo Golborne C, Downie LE. Omega-3 supplementation is neuroprotective to corneal nerves in dry eye disease: a pilot study. Ophthalmic Physiol Opt. 2017 Jul;37(4):473-481.
[19] Brignole-Baudouin F, Baudouin C, Aragona P, Rolando M, Labetoulle M, Pisella PJ, Barabino S, Siou-Mermet R, Creuzot-Garcher C. A multicentre, double-masked, randomized, controlled trial assessing the effect of oral supplementation of omega-3 and omega-6 fatty acids on a conjunctival inflammatory marker in dry eye patients. Acta Ophthalmol. 2011 Nov;89(7):e591-7.
[20] Creuzot C, Passemard M, Viau S, Joffre C, Pouliquen P, Elena PP, Bron A, Brignole F. Amélioration de la symptomatologie chez des patients atteints de sécheresse oculaire et traités oralement par des acides gras polyinsaturés [Improvement of dry eye symptoms with polyunsaturated fatty acids]. J Fr Ophtalmol. 2006 Oct;29(8):868-73. French.
[21] Rolando M, Barabino S. Dry eye disease: what is the role of vitamin D?. International journal of molecular sciences. 2023 Jan 11;24(2):1458.
[22] Liu J, Dong Y, Wang Y. Vitamin D deficiency is associated with dry eye syndrome: a systematic review and meta‐analysis. Acta Ophthalmologica. 2020 Dec;98(8):749-54.
[23] McCusker MM, Durrani K, Payette MJ, Suchecki J. An eye on nutrition: The role of vitamins, essential fatty acids, and antioxidants in age-related macular degeneration, dry eye syndrome, and cataract. Clinics in dermatology. 2016 Mar 1;34(2):276-85.
[24] Perényi K, Dienes L, Kornafeld A, Kovács B, Kiss HJ, Szepessy Z, Nagy ZZ, Barsi Á, Acosta MC, Gallar J, Kovács I. The effect of tear supplementation with 0.15% preservative-free zinc-hyaluronate on ocular surface sensations in patients with dry eye. Journal of Ocular Pharmacology and Therapeutics. 2017 Jul 1;33(6):487-92.
[25] Yang YJ, Lee WY, Kim YJ, Hong YP. A meta-analysis of the efficacy of hyaluronic acid eye drops for the treatment of dry eye syndrome. International journal of environmental research and public health. 2021 Mar 1;18(5):2383.
[26] Troiano P, Monaco G. Effect of hypotonic 0.4% hyaluronic acid drops in dry eye patients: a cross-over study. Cornea. 2008 Dec 1;27(10)
[27] Li H, Li J, Hou C, Li J, Peng H, Wang Q. The effect of astaxanthin on inflammation in hyperosmolarity of experimental dry eye model in vitro and in vivo. Experimental Eye Research. 2020 Aug 1;197:108113.
[28] Tian L, Wen Y, Li S, Zhang P, Wang Y, Wang J, Cao K, Du L, Wang N, Jie Y. Benefits and Safety of Astaxanthin in the treatment of mild-to-moderate Dry eye Disease. Frontiers in Nutrition. 2022 Jan 13;8:796951.
[29] Pescosolido N, Imperatrice B, Koverech A, Messano M. L-carnitine and short chain ester in tears from patients with dry eye. Optometry and Vision Science. 2009 Feb 1;86(2):E132-8.
[30] Pescosolido N, Imperatrice B, Karavitis P. The aging eye and the role of L-carnitine and its derivatives. Drugs in R & D. 2008 Dec;9:3-14.
[31] Hu J, Kong L, Zhu S, Ju M, Zhang Q. Efficacy and safety of manuka honey for dry eye. Clinical and Experimental Optometry. 2023 Jul 4;106(5):455-65.
[32] Prinz J, Maffulli N, Fuest M, Walter P, Hildebrand F, Migliorini F. Honey-related treatment strategies in dry eye disease. Pharmaceuticals. 2023 May 18;16(5):762.
[33] Lee G. Evidence-Based Strategies for Warm Compress Therapy in Meibomian Gland Dysfunction. Ophthalmology and Therapy. 2024 Sep;13(9):2481-93.
[34] Zhou X, Shen Y, Shang J, Zhou X. Effects of warm compress on tear film, blink pattern and Meibomian gland function in dry eyes after corneal refractive surgery. BMC ophthalmology. 2021 Dec;21:1-1.