
Gastroesophageal Reflux Disease

Description
This page has 56 references
"Gastroesophageal Reflux Disease (GERD)" is a chronic digestive condition where stomach acid frequently backs up into the esophagus. This happens when the lower esophageal sphincter weakens, causing burning pain, regurgitation, and discomfort after meals. Triggers include fatty foods, alcohol, and late-night eating. Without treatment, GERD can cause complications like esophagitis or Barrett’s esophagus. Long-term management includes avoiding trigger foods, eating smaller meals, and using acid-reducing medications to protect the esophagus and ease daily symptoms.
Symptoms & Signs
Body System
Digestive System
Causes
Overeating, Obesity, Cigarette Smoking, Diet, Alcohol, Coffee, Carbonated Drinks, Stress
Things To Do
Various natural remedies and lifestyle adjustments can swiftly alleviate the symptoms of GERD. Dietary modifications include:
Consume your largest meal at midday to allow for proper digestion.
Keep breakfast and supper small yet nutrient-dense to avoid feelings of hunger.
Opt for easily digestible, light, boiled, or steamed foods, incorporating vegetables, high-quality natural yogurts, rice, whole grains, cottage cheese, and vegetable juices.
Finish your last meal of the day by 6 p.m., giving your body sufficient time to process it before bedtime.
Use mild spices in your meals.
Include fruits rich in digestive enzymes, such as pineapples, kiwis, and mangoes.
Stay hydrated throughout the day, avoiding excessive water intake during meals.
For more intensive measures,
Consider a vegetable-juice-only diet for a couple of days, especially if GERD is severe. Including cabbage juice, known for relieving symptoms, can be beneficial. However, consult a medical professional before starting such a restrictive diet to ensure there are no medical contraindications.
Additionally, consider:
Working towards weight loss.
Implementing stress reduction techniques.
Sleeping with your head elevated at night.
Exploring chiropractic care as a potential supportive measure.
Things To Avoid
For individuals dealing with GERD, it's essential to be mindful of the circumstances surrounding its occurrence.
Certain foods and beverages, like coffee, alcohol, fruit juices, chocolate, citrus fruits, fried foods, and tomatoes, are known triggers for acid reflux. If any item in your diet is associated with this condition, remove it promptly.
Stress, smoking, and excess weight can also contribute to GERD.
Additionally, consider these dietary recommendations to reduce the risk of its onset:
Avoid consuming large meals close to bedtime.
Practice moderation and avoid overeating, as large meals take longer to digest.
Refrain from eating or snacking after 6 p.m.
Avoid drinking water or any beverages, especially carbonated ones, before, during, or immediately after meals, as they can dilute and weaken stomach acid.
Steer clear of greasy, fatty, and fried foods.
Skip spicy foods.
Consider minimizing or eliminating meat consumption, especially during acid reflux episodes, with a focus on avoiding cold-cut meats.
Supplements
Direct Support
(Most Helpful → Least Helpful)
These supplements directly affect GERD by reducing stomach acid, soothing the esophageal lining, or improving lower esophageal sphincter function.
Melatonin: Melatonin improves esophageal sphincter function, reducing the likelihood of acid reflux by moderating gastric acid secretion and supporting better digestive health.
Betaine HCI: Betaine HCI increases stomach acidity, improving the breakdown of food and helping close the lower esophageal sphincter, reducing the discomfort associated with low stomach acid.
Vitamin D: Vitamin D supports muscle contraction and reduces inflammation, helping maintain the function of the esophageal sphincter, which may improve digestion and reduce discomfort.
Methylsulfonylmethane [MSM]: MSM protects the stomach lining by reducing inflammation and irritation caused by stomach acid, helping alleviate discomfort and promoting digestive health.
D-Limonene: D-limonene helps coat the esophagus and reduces reflux symptoms by supporting normal muscle movement in the digestive tract. It is often used to relieve heartburn and may reduce the frequency of acid episodes.
Indirect Support
(Most Helpful → Least Helpful)
These supplements do not target GERD directly but may support digestive efficiency, reduce inflammation, or improve stress resilience that influences reflux severity.
Probiotics: Probiotics help balance gut bacteria, reducing inflammation and supporting the health of the esophageal sphincter, which may lower the frequency of acid reflux episodes.
Omega 3: Omega-3’s anti-inflammatory effects help reduce inflammation in the digestive system, promoting a healthier digestive tract and easing discomfort caused by irritation.
Magnesium: Magnesium helps regulate muscle tone in the digestive system and may support the proper function of the lower esophageal sphincter. It also plays a role in maintaining healthy acid levels in the stomach.
Natural Compounds
These natural compounds may help manage GERD by soothing the digestive tract, improving acid balance, or protecting the esophageal lining.
Sodium Bicarbonate: Sodium bicarbonate neutralizes excess stomach acid and can provide quick relief from heartburn. It is commonly used for occasional symptoms but may cause rebound acid if overused.
Manuka Honey: Manuka honey helps coat and soothe the esophageal lining, potentially easing irritation from chronic acid exposure. Its anti-inflammatory and antimicrobial effects may support digestive health, and anecdotal evidence suggests it helps manage GERD symptoms.
Bone Broth: Bone broth may help soothe the esophageal lining and support tissue recovery during ongoing irritation. Its use in GERD is anecdotal, based on general gut-soothing effects rather than direct anti-reflux action.
Apple Cider Vinegar: Apple cider vinegar, based on anecdotal evidence, may help balance stomach acid levels and improve digestion when consumed diluted before meals, potentially easing discomfort.
Plant Extracts
Direct Support
(Most Helpful → Least Helpful)
These plant extracts directly support relief from GERD by calming gastric irritation, enhancing mucosal protection, or aiding stomach acid regulation.
Slippery Elm: Slippery Elm’s mucilage coats the esophagus and stomach, forming a soothing barrier against stomach acid, reducing irritation, and supporting the healing of inflamed tissues.
Licorice Root Extract: Licorice root, containing glycyrrhizin, promotes mucus production to create a protective barrier along the stomach and esophagus lining. This natural shield helps reduce acid irritation and supports the healing of digestive tissues.
Marshmallow Root Extract: Marshmallow root forms a protective coating over the esophagus, helping soothe irritation and inflammation caused by acid exposure, promoting relief.
Aloe Vera Juice: Aloe Vera’s anti-inflammatory properties soothe the esophagus and promote healing by reducing irritation caused by stomach acid exposure.
Ginger Extract: Ginger’s anti-inflammatory compounds, like gingerol, help reduce esophageal irritation and promote digestion by regulating esophageal sphincter function.
Fennel Extract: Fennel extract is traditionally used to ease digestive discomfort such as gas and bloating, which can increase pressure and worsen reflux. Its calming effect on the gut may offer mild symptom relief.
Indirect Support
(Most Helpful → Least Helpful)
These extracts do not act directly on GERD but may promote digestive balance, reduce oxidative stress, or support gut-liver interaction.
Cumin Extract: Cumin stimulates digestive juices, improving digestion and reducing indigestion by enhancing bile and enzyme production, which helps ease discomfort after meals.
Chamomile Tea: Chamomile’s anti-inflammatory properties help relax the digestive muscles, supporting better digestion and potentially reducing the occurrence of digestive discomfort.
Curcumin: Curcumin reduces inflammation in the digestive tract by inhibiting key inflammatory pathways, promoting better digestion and alleviating symptoms related to irritation.
Alternative Treatments
These alternative therapies support digestive comfort, reduce reflux-related irritation, and promote internal balance in individuals with GERD.
Acupuncture: Acupuncture stimulates points like PC6 (Neiguan) on the inner forearm and ST36 (Zusanli) just below the knee, promoting digestive health and reducing discomfort by improving energy flow and relaxing the digestive tract.
Acupressure: Acupressure involves applying pressure to points like PC6 (Neiguan) on the inner forearm and CV12 (Zhongwan) on the upper abdomen, stimulating digestive function and relieving discomfort caused by acid imbalance.
Ayurveda: Ayurvedic treatments incorporate dietary changes and herbal remedies to support digestion, balancing the body’s natural energy and promoting digestive health.
Aromatherapy: Aromatherapy using essential oils like peppermint or ginger may help relax the digestive tract when inhaled or applied topically, offering relief from digestive discomfort.
Biofeedback: Biofeedback techniques help individuals regulate physiological responses, such as muscle tension, which may contribute to better digestion and reduce discomfort.
Chiropractic Care: Chiropractic care adjustments can improve spinal alignment, potentially enhancing nerve function and supporting digestive health by promoting better gastrointestinal motility.
Mindfulness Meditation: Meditation may reduce stress-related reflux by calming the nervous system and supporting healthier digestion. Its role in GERD is anecdotal and mainly tied to stress management benefits.
Functional Lab Tests You May Wish to Explore
Books Worth Considering for Deeper Insight
Currently, no high-quality books meeting our functional, integrative, and natural healing standards are available for this condition. As soon as trusted resources are published, we will review and feature them here.
Podcasts That Offer Valuable Perspectives
Currently, no high-quality books meeting our functional, integrative, and natural healing standards are available for this condition. As soon as trusted resources are published, we will review and feature them here.
Educational Videos To Learn From
How Key Nutrients Support the Body
Amino Acids: Amino acids serve as the building blocks of proteins, crucial for muscle growth and repair. Additionally, they play key roles in maintaining proper pH levels, storing nitrogen, synthesizing hormones, and facilitating enzymatic reactions.
Fatty Acids: Fatty acids serve as energy sources, structural components of cell membranes, and precursors to signaling molecules. Essential fatty acids, like omega-3 and omega-6, play critical roles in brain function, cardiovascular health, and inflammation regulation.
Herbal Extracts: Herbal extracts contain bioactive compounds with various medicinal properties, including antioxidant, anti-inflammatory, and antimicrobial effects. They have been used traditionally to support digestion, immunity, and overall health.
Other Nutrients: Other nutrients encompass a wide array of essential compounds crucial for various physiological functions. This category includes neurotransmitters and their precursors, which facilitate nerve signaling and are vital for central nervous system function. Additionally, naturally occurring structural components and biological detergents, such as phospholipids and bile salts, play critical roles in tissue repair, fat digestion, and overall bodily function. Phospholipids contribute to cell membrane integrity and fat emulsification, while bile salts are key to digesting and absorbing dietary fats. Hormones and their precursors regulate numerous physiological processes, including metabolism, growth, and reproduction. Furthermore, naturally occurring chemicals and metals play pivotal roles in enzymatic reactions, immune function, and overall health maintenance.
Probiotics: Probiotics are live microorganisms that confer health benefits when consumed. They support gut health, immune function, and oral hygiene by promoting the growth of beneficial bacteria and inhibiting the growth of harmful pathogens.
Vitamins: Vitamins are essential micronutrients that play diverse roles in supporting cellular processes, immune function, and overall health. They must be obtained through diet or supplementation to ensure proper bodily function.
Essential Nutrients Explained
References
[1] Kelly GS. Hydrochloric Acid: Physiological Functions and Clinical Implications. Alternative Medicine Review. 1997, Vol 2, Issue 2, pp 116-127.
[2] Rémond D, Shahar DR, Gille D, et al. Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition. Oncotarget. 2015;6(16):13858-13898.
[3] Kines K, Krupczak T. Nutritional Interventions for Gastroesophageal Reflux, Irritable Bowel Syndrome, and Hypochlorhydria: A Case Report. Integr Med (Encinitas). 2016;15(4):49-53.
[4] Johnston J, Coon CN. The use of varying levels of pepsin for pepsin digestion studies with animal proteins. Poultry Science. 1979, Vol 58, Issue 5, pp 1271-1273.
[5] Vanvi A, Tsopmo A. Pepsin Digested Oat Bran Proteins: Separation, Antioxidant Activity, and Identification of New Peptides. Journal of Chemistry. 2016.
[6] Rigaud D, Paycha F, Meulemans A, Merrouche M, Mignon M. Effect of psyllium on gastric emptying, hunger feeling and food intake in normal volunteers: a double blind study. European Journal of Clinical Nutrition. 1998 52, 239-245.
[7] Tamargo A, Cueva C, Alvarez MD, Herranz B, Moreno-Arribas MV, Laguna L. Physical effects of dietary fibre on simulated luminal flow, studied by in vitro dynamic gastrointestinal digestion and fermentation. Food Funct. 2019, 10, 3452-3465.
[8] Odes HS, Madar Z. A double-blind trial of a celandin, aloevera and psyllium laxative preparation in adult patients with constipation. Digestion. 1991;49(2):65-71.
[9] Uberti F, Bardelli C, Morsanuto V, Ghirlanda S, Molinari C. Role of vitamin D3 combined to alginates in preventing acid and oxidative injury in cultured gastric epithelial cells. BMC Gastroenterol. 2016;16(1):127.
[10] Higdon J. Vitamin D. Oregon State University: Linus Pauling Institute. 2000.
[11] Zhuang ZH, Xie JJ, Wei JJ, Tang DP, Yang LY. The effect of n-3/n-6 polyunsaturated fatty acids on acute reflux esophagitis in rats. Lipids Health Dis. 2016;15(1):172.
[12] Sun J. D-Limonene: safety and clinical applications. Alternative Medicine Review : a Journal of Clinical Therapeutic. 2007 Sep;12(3):259-264.
[13] Jarosz M, Taraszewska A. Risk factors for gastroesophageal reflux disease: the role of diet. Prz Gastroenterol. 2014;9(5):297-301.
[14] Shakeri F, Gholamnezhad Z, Mégarbane B, Rezaee R, Boskabady MH. Gastrointestinal effects of Nigella sativa and its main constituent, thymoquinone: a review. Avicenna J Phytomed. 2016;6(1):9-20.
[15] Srinivasan K. Cumin (Cuminum cyminum) and black cumin (Nigella sativa) seeds: traditional uses, chemical constituents, and nutraceutical effects. Food Quality and Safety. 2018, Vol 2, Issue 1, pp 1–16.
[16] Ried K, Travica N, Dorairaj R, Sali A. Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders. Nutr Res. 2020;76:37-51.
[17] Watts, Christopher & Rousseau, Bernard. (2012). Slippery Elm, its Biochemistry, and use as a Complementary and Alternative Treatment for Laryngeal Irritation. Journal of Investigational Biochemistry. 1. 17-23.
[18] Hybrid protocols plus natural treatments for inflammatory conditions. Posit Health News. 1998;(No 17):16-18.
[19] Panahi Y, Khedmat H, Valizadegan G, Mohtashami R, Sahebkar A. Efficacy and safety of Aloe vera syrup for the treatment of gastroesophageal reflux disease: a pilot randomized positive-controlled trial. J Tradit Chin Med. 2015;35(6):632-636.
[20] Keshavarzi Z, Rezapour TM, Vatanchian M, et al. The effects of aqueous extract of Aloe vera leaves on the gastric acid secretion and brain and intestinal water content following acetic acid- induced gastric ulcer in male rats. Avicenna J Phytomed. 2014;4(2):137-143.
[21] Hęś, M., Dziedzic, K., Górecka, D. et al. Aloe vera (L.) Webb.: Natural Sources of Antioxidants – A Review. Plant Foods Hum Nutr 74, 255–265 (2019).
[22] Amirshahrokhi K, Khalili AR. Methylsulfonylmethane is effective against gastric mucosal injury. Eur J Pharmacol. 2017;811:240-248.
[23] Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017;9(3):290. Published 2017 Mar 16.
[24] Cheng J, Ouwehand AC. Gastroesophageal reflux disease and probiotics: a systematic review. Nutrients. 2020 Jan 2;12(1):132.
[25] Indrio F, Cristofori F. GER and Probiotic. InGastroesophageal Reflux in Children 2022 Jun 24 (pp. 189-200). Cham: Springer International Publishing.
[26] Werbach MR. Melatonin for the treatment of gastroesophageal reflux disease. Alternative Therapies in Health and Medicine. 2008 Jul 1;14(4):54-9.
[27] Brzozowska I, Strzalka M, Drozdowicz D, J Konturek S, Brzozowski T. Mechanisms of esophageal protection, gastroprotection and ulcer healing by melatonin. implications for the therapeutic use of melatonin in gastroesophageal reflux disease (GERD) and peptic ulcer disease. Current pharmaceutical design. 2014 Sep 1;20(30):4807-15.
[28] Kathy Abascal BS. Herbs for Gastroesophageal Reflux Disease. ALTERNATIVE AND COMPLEMENTARY THERAPIES. 2010 Dec.
[29] Bhardwaj K, Kishore L. Natural remedies: For gastroesophageal reflux. Journal of Medicinal Plants. 2021;9(4):114-8.
[30] Cheung T, Hailemeskel B, Fullas F. A survey on the treatment of GERD with aloe vera juice, slippery elm, ginger tea, and chamomile tea. GSC Biological and Pharmaceutical Sciences. 2024;26(1):199-206.
[31] Sarkar M, Chawla P. Curative Properties of Chamomile in Gastrointestinal Disorders. InHerbs, Spices, and Medicinal Plants for Human Gastrointestinal Disorders 2022 Aug 25 (pp. 125-140). Apple Academic Press.
[32] Hosseinkhani A, Lankarani KB, Mohagheghzadeh A, Long C, Pasalar M. An evidence-based review of medicinal herbs for the treatment of gastroesophageal reflux disease (GERD). Current Drug Discovery Technologies. 2018 Dec 1;15(4):305-14.
[33] Herdiana Y. Functional Food in Relation to Gastroesophageal Reflux Disease (GERD). Nutrients. 2023 Aug 15;15(16):3583.
[34] Lee JA, Kim MJ, Shin MR, Seo BI, Roh SS. The Study of Anti-inflammatory Effect of Curcumae Longae Rhizoma 30% EtOH Extract on Chronic Acid Reflux Esophagitis Rats.
[35] Mahattanadul S, Radenahmad N, Phadoongsombut N, et al. Effects of curcumin on reflux esophagitis in rats. J Nat Med. 2006;60(3):198-205.
[36] Trinh DT, Tran AH, Bui MM, Vuong NL. Thread-embedding acupuncture may improve symptom resolution in patients with gastroesophageal reflux disease: A randomized controlled trial. Integrative medicine research. 2023 Sep 1;12(3):100971.
[37] Dickman R, Schiff E, Holland A, Wright C, Sarela SR, Han B, Fass R. Clinical trial: acupuncture vs. doubling the proton pump inhibitor dose in refractory heartburn. Alimentary pharmacology & therapeutics. 2007 Nov;26(10):1333-44.
[38] Zhang Y, Huang MZ, Pan CQ, Liu HW, Lu YX, Tan JJ, Xie S. Analysis of feasibility of application of Beishu point acupressure therapy in treating gastroesophageal reflux disease via AMPK/ULK1 mediated autophagy pathway based on" adjusting central axis via pivot" theory. Journal of Hainan Medical College. 2021 Nov 1;27(21).
[39] Yan M, Shi Y, Liu Y, Shi Y, Zhang M, Chen D, Ye S, Li S, Feng Y. Systematic Review and Meta-analysis of Randomized Controlled Trials on Manual Therapy for the Treatment of Gastroesophageal Reflux Disease. Chinese medicine and natural products. 2023 Dec;3(04):e143-57.
[40] Padmaveer PS, Sagare SS. A review on Ayurveda dietetics for Amlapitta (Gastroesophageal Reflux Disease) by different Ayurveda classical texts. Journal of Ayurveda and Integrated Medical Sciences. 2023 Dec 29;8(11):140-4.
[41] Amarprakash D, Anaya P, Kulkarni AM. Management of amla-pitta (gastroesophageal reflux disease) by ayurveda drugs: a case study. Int J Health Sci. 2022.
[42] Sun X, Shang W, Wang Z, Liu X, Fang X, Ke M. Short-term and long-term effect of diaphragm biofeedback training in gastroesophageal reflux disease: an open-label, pilot, randomized trial. Diseases of the Esophagus. 2016 Oct 1;29(7):829-36.
[43] Whitehead WE. Biofeedback in the treatment of gastrointestinal disorders. Biofeedback Self Regul. 1978;3(4):375-384.
[44] Angus K, Asgharifar S, Gleberzon B. What effect does chiropractic treatment have on gastrointestinal (GI) disorders: a narrative review of the literature. The Journal of the Canadian Chiropractic Association. 2015 Jun;59(2):122.
[45] Hains G, Hains F, Descarreaux M. Gastroesophageal Reflux Disease, Spinal Manipulative Therapy and Ischemic Compression: A Preliminary Study. Journal of the American Chiropractic Association. 2007 Jan 1;44(1).
[46] Sun J. D-Limonene: safety and clinical applications. Alternative medicine review. 2007 Sep 1;12(3):259.
[47] Komolafe K, Komolafe TR, Crown OO, Ajiboye B, Noubissi F, Ogungbe IV, Graham B. Natural Products in the Management of Gastroesophageal Reflux Disease: Mechanisms, Efficacy, and Future Directions. Nutrients. 2025 Mar 19;17(6):1069.
[48] Gobind A. The role of magnesium supplement in laryngopharyngeal reflux disease. Int J Otorhinolaryngol Head Neck Surg [Internet]. 2021 Dec. 23 [cited 2025 Apr. 30];8(1):47-52.
[49] Christiansen J, Rehfeld JF, Stadil F. Interaction of calcium and magnesium on gastric acid secretion and serum gastrin concentration in man. Gastroenterology. 1975;68(5 Pt 1):1140-1143.
[50] Samimi S, Nimrouzi M, Zarshenas MM, Fallahzadeh E, Vardanjani HM, Sadeghi E, Salehi Z. The efficacy of a traditional herbal medicine compound for functional dyspepsia: a randomized, double-blind, placebo-controlled trial. Jundishapur Journal of Natural Pharmaceutical Products. 2024;19(4).
[51] Tanveer M, Wagner C, ul Haq MI, Ribeiro NC, Rathinasabapathy T, Butt MS, Shehzad A, Komarnytsky S. Spicing up gastrointestinal health with dietary essential oils. Phytochemistry Reviews. 2020 Apr;19:243-63.
[52] Labenz J, Anschütz M, Walstab J, Wedemeyer RS, Wolters H, Schug B. Heartburn relief with bicarbonate-rich mineral water: results of the randomised, placebo-controlled phase-III trial STOMACH STILL. BMJ Open Gastroenterol. 2023;10(1):e001048.
[53] Adams WL, Welch CS, Clark BB. The effect of sodium bicarbonate on gastric secretion. American Journal of Physiology-Legacy Content. 1943 Jul 1;139(3):356-63.
[54] Bowen BK, Krause WJ, Ivey KJ. Effect of sodium bicarbonate on aspirin-induced damage and potential difference changes in human gastric mucosa. Br Med J. 1977 Oct 22;2(6094):1052-5.
[55] Chandran S, Raman R, Kishor M, Nandeesh HP. The effectiveness of mindfulness meditation in relief of symptoms of depression and quality of life in patients with gastroesophageal reflux disease. Indian Journal of Gastroenterology. 2019 Feb 14;38:29-38.
[56] Chandran S, Raman R, Kishor M, Nandeesh HP. A randomized control trial of mindfulness-based intervention in relief of symptoms of anxiety and quality of life in gastroesophageal reflux disease. Annals of Indian Psychiatry. 2023 Apr 1;7(2):107-14.