
Description
"Benfotiamine" is a fat-soluble form of vitamin B1 (thiamine), naturally present in trace amounts in garlic, onions, and other allium vegetables. This compound interacts with enzymatic pathways involved in glucose metabolism, oxidative stability, and biochemical signaling. Once converted into thiamine, benfotiamine engages with metabolic processes linked to nerve function, vascular activity, and cellular homeostasis. It also participates in carbohydrate metabolism and energy regulation. As a bioactive compound, benfotiamine contributes to physiological processes essential for metabolic efficiency.
Functions in the Body
Category
Deficiency Symptoms
Benfotiamine works synergistically with vitamin B1 (thiamin) to support glucose metabolism and nerve health. It helps boost the efficacy of thiamin in addressing issues related to hyperglycemia and oxidative stress. There are no significant antagonistic interactions reported for benfotiamine.
Synergists & Antagonists
Benfotiamine is commonly paired with vitamin B1 (thiamine) and alpha-lipoic acid to support nerve function and glucose metabolism, which may help in conditions related to neuropathic pain. No known antagonistic effects have been reported.

Benfotiamine
Warnings
Benfotiamine supplementation is generally safe, but excessive intake may interfere with normal thiamine metabolism. Individuals with diabetes or low blood pressure should consult a healthcare provider before use.
Food Sources
Benfotiamine is a synthetic derivative of thiamine and is not found in common food sources.
Time Frame
Benfotiamine is best taken with meals that contain fat to enhance absorption, as it is fat-soluble.
Depleted By
Benfotiamine is not depleted by any specific dietary or lifestyle factors.