Description
"Diindolylmethane" (DIM) is a bioactive compound derived from indole-3-carbinol, naturally occurring in cruciferous vegetables like broccoli and kale. This compound helps regulate estrogen metabolism, promoting hormonal equilibrium and endocrine stability. It also plays a role in detoxification pathways that regulate cellular integrity and metabolic adaptation. In addition, DIM interacts with immune signaling, supporting inflammatory responses. Widely recognized for its metabolic activity, it remains an essential element in endocrine health and cellular function.
Functions in the Body
Category
Deficiency Symptoms
There are no known deficiency symptoms associated with a lack of diindolylmethane.
Synergists & Antagonists
DIM plays a role in hormone balance and may benefit from a combination with indole-3-carbinol, calcium D-glucarate, and sulforaphane. There are no significant antagonistic interactions.
Diindolylmethane
Warnings
Individuals on hormone replacement therapy or medications that affect estrogen levels should consult a healthcare professional before using DIM, as it may influence estrogen metabolism. Pregnant or breastfeeding women are advised to seek medical guidance before supplementation.
Food Sources
Diindolylmethane is obtained primarily from cruciferous vegetables, with the highest concentrations found in broccoli, Brussels sprouts, cabbage, and kale.
Time Frame
DIM can be taken at any time of the day, with or without food.
Depleted By
Diindolylmethane does not get depleted in the body, as it is a non-essential compound.