
Description
"Histidine" is an essential amino acid involved in tissue repair, nerve protection, and metabolic balance. It contributes to myelin production, ensuring nerve cell insulation, while also supporting red and white blood cell formation. This amino acid participates in detoxification by binding to heavy metals and assists in cardiovascular function by regulating blood pressure. As a precursor to histamine, it influences immune responses and inflammation. Maintaining adequate histidine levels is important for cellular and metabolic health.
Functions in the Body
Category
Deficiency Symptoms
A deficiency in histidine may lead to joint pain, eczema, cataracts, rheumatoid arthritis, and nerve deafness.
Synergists & Antagonists
Histidine has an antagonistic relationship with methionine, as excess methionine can reduce histidine levels. Histidine aids in the synthesis of histamine when combined with vitamin B3 (niacin) and vitamin B6 (pyridoxine).

Histidine
Warnings
Excess histidine in the body may contribute to psychological disorders such as schizophrenia and anxiety. Use caution when supplementing during pregnancy, breastfeeding, or when experiencing folic acid deficiency.
Food Sources
Rich sources of histidine include nutritional yeast, beef, pork, chicken, eggs, legumes, tuna, tofu, pumpkin seeds, and squash seeds.
Time Frame
Histidine can be taken at any time, making it convenient to incorporate into meals throughout the day.
Depleted By
A diet deficient in histidine or protein can deplete histidine levels in the body.