
Description
"Oligomeric Proanthocyanidins" (OPCs) are powerful antioxidants found in grape seeds, pine bark, and certain berries. Known for their ability to cross the blood-brain barrier, they help protect neural tissues from oxidative stress. By modulating inflammation, OPCs support immune function and histamine regulation. Cardiovascular benefits include strengthening blood vessels and reducing oxidative damage. They also contribute to collagen stability, enhancing skin resilience. Widely consumed through plant-based foods, OPCs continue to be valued for their protective properties.
Functions in the Body
Category
Deficiency Symptoms
Since OPCs are not classified as essential nutrients, there are no specific deficiency symptoms linked to their absence.
Synergists & Antagonists
OPCs work synergistically with glutathione to boost the effectiveness of vitamin C, enhancing antioxidant defense and reducing oxidative stress. OPCs can interact with blood-thinning medications, so caution is advised when taken alongside anticoagulants.

Oligomeric Proanthocyanidins
Warnings
OPCs can interact with blood thinners, increasing the risk of bleeding. Caution should also be applied for people with clotting disorders or those preparing for surgery. Always consult a healthcare provider before taking OPCs, especially if on medication.
Food Sources
OPCs are naturally found in grape skin, grape seeds, apples, pears, red wine, blueberries, cranberries, bilberries, black currants, strawberries, raspberries, hazelnuts, pecans, and pistachios.
Time Frame
OPCs are best consumed in the morning on an empty stomach for optimal absorption and antioxidant support.
Depleted By
There are no known dietary or lifestyle factors that deplete OPC levels in the body.