
Description
"Phosphatidylserine" is a naturally occurring phospholipid essential for brain health and cognitive function. By supporting neurotransmitter activity, it enhances focus, memory, and learning capacity. Its role in stress modulation helps regulate cortisol levels and emotional balance. Furthermore, phosphatidylserine assists in cellular communication, influencing neural plasticity. As an integral part of cell membranes, it contributes to systemic adaptation and mental clarity. Sourced from plant-based and animal-derived foods, phosphatidylserine remains fundamental for cognitive resilience.
Functions in the Body
Category
Deficiency Symptoms
A deficiency in phosphatidylserine can result in impaired mental function, memory issues, and symptoms of depression.
Synergists & Antagonists
Phosphatidylserine works synergistically with folic acid, vitamin B12, vitamin C, and omega-3 fatty acids to support cognitive function and brain health. These nutrients contribute to phosphatidylserine synthesis and function. No well-documented antagonistic interactions exist.

Phosphatidylserine
Warnings
Phosphatidylserine should be used with caution during pregnancy and breastfeeding. It may interact with blood thinners, anti-inflammatory medications for arthritis or pain, and some athletic performance-enhancing supplements.
Food Sources
Phosphatidylserine can be found in foods such as white beans, egg yolks, chicken liver, beef liver, and soy lecithin.
Time Frame
For optimal absorption, phosphatidylserine should be taken with a meal, as it is fat-soluble.
Depleted By
Phosphatidylserine (PS) levels are depleted by the inhibition of acid sphingomyelinase (ASM), natural aging, and prolonged stress, which can reduce PS levels in the brain.