Description
"Trimethylglycine" (TMG) is a naturally occurring compound found in beets, whole grains, and seafood. It participates in methylation processes that regulate homocysteine levels, cardiovascular function, and cellular metabolism. This nutrient also promotes liver detoxification and energy production, supporting metabolic efficiency. Often included in diets for maintaining overall balance, it plays a role in biochemical stability. Long recognized in nutritional science, TMG continues to be valued for its role in cellular function.
Functions in the Body
Category
Deficiency Symptoms
A deficiency of trimethylglycine may lead to high homocysteine levels, which increases the risk of cardiovascular diseases.
Synergists & Antagonists
TMG works synergistically with vitamin B6, vitamin B12, and folic acid to lower homocysteine levels. It also supports adrenal function in synergy with vitamin B5, vitamin B6, vitamin C, and tyrosine. No well-documented antagonistic interactions exist.
Trimethylglycine
Warnings
Individuals with kidney disease should avoid TMG. Caution is advised during pregnancy, breastfeeding, and in cases of high cholesterol, as it may interact with cholesterol-lowering medications.
Food Sources
TMG is naturally found in beets, spinach, shellfish, grains, and broccoli.
Time Frame
TMG is best taken in the morning to support methylation and energy production.
Depleted By
There are no well-documented factors that directly deplete TMG in the body.