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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Estrogens Total

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ET

Description

Estrogens Total test measures three types of estrogen in your blood—estrone (E1), estradiol (E2), and estriol (E3)—to assess your hormonal health. Your doctor may recommend this test if you’re experiencing symptoms such as irregular periods, infertility, hot flashes, or other hormonal concerns. A simple blood test measures your estrogen levels, helping you and your doctor understand your hormonal health and overall well-being. Results that aren’t within the normal range could indicate conditions such as PCOS, menopause, or hypogonadism. In rare cases, abnormal results may suggest serious concerns, like ovarian tumors or hormone-related cancers, but these findings are uncommon and typically require additional tests to confirm. Women with hypogonadism or menopause have lower estrogen levels. However, higher estrogen levels may indicate hormonal imbalance or, less often, ovarian growths. Your doctor will discuss test results with you to identify issues. Your doctor and you can create a personalized care plan. Regular estrogen monitoring can help you understand hormonal changes and take health-promoting steps.

Estrogens Total test measures three types of estrogen in your blood—estrone (E1), estradiol (E2), and estriol (E3)—to assess your hormonal health. Your doctor may recommend this test if you’re experiencing symptoms such as irregular periods, infertility, hot flashes, or other hormonal concerns. A simple blood test measures your estrogen levels, helping you and your doctor understand your hormonal health and overall well-being. Results that aren’t within the normal range could indicate conditions such as PCOS, menopause, or hypogonadism. In rare cases, abnormal results may suggest serious concerns, like ovarian tumors or hormone-related cancers, but these findings are uncommon and typically require additional tests to confirm. Women with hypogonadism or menopause have lower estrogen levels. However, higher estrogen levels may indicate hormonal imbalance or, less often, ovarian growths. Your doctor will discuss test results with you to identify issues. Your doctor and you can create a personalized care plan. Regular estrogen monitoring can help you understand hormonal changes and take health-promoting steps.

Procedure

Invasive

Sample Type

Blood – Serum

Test Category

Hormones

Procedure Category

Blood Draw

Units

Picograms Per Milliliter | Picomoles Per Liter

Test Groups

Hormone Health Group: Its focus is on evaluating hormone levels and function, providing insights into hormonal balance and associated health conditions. Male Hormone Group: It focuses on assessing hormone levels specific to male health, providing insights into reproductive function and hormonal balance.

Optimal Range

Men:

  • Conventional Unit: 60–100 pg/mL | SI Unit: 220.2–367.0 pmol/L


Women:

  • Conventional Unit: Not Available (Premenopausal) | Not Available (Postmenopausal)

  • SI Unit: Not Available (Premenopausal) | Not Available (Postmenopausal)

Normal Range

Men:

  • Conventional Unit: 60–190 pg/mL | SI Unit: 220.2–697.0 pmol/L


Women:

  • Conventional Unit: 50–170 pg/mL (Premenopausal) | 0–30 pg/mL (Postmenopausal)

  • SI Unit: 183.5–624.7 pmol/L (Premenopausal) | 0–110.3 pmol/L (Postmenopausal)

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Adrenal tumor (Tumor originating in the adrenal glands)

  • Cirrhosis (Liver disease characterized by scarring of the liver tissue)

  • Hepatic nephrosis (Kidney disease associated with liver dysfunction)

  • Hyperthyroidism (Overactive thyroid gland)

  • Normal pregnancy

  • Ovarian tumor (Tumor originating ...

Key Reasons For Testing

  • Hormone Measurement: Total estrogen testing evaluates estrone (E1), estradiol (E2), and estriol (E3) levels in the bloodstream.

  • Endocrine Function: Provides insights into ovarian health, menopausal status, and estrogen-related disorders.

  • Menstrual Cycle Monitoring: Assesses estrogen fluctuations during the menstrual cycle to evaluate fertility.

  • Menopausal Transition: Helps diagnose menopause and guide hormone replacement therapy.

  • Estrogen Disorders: Identifies conditions like PCOS or estrogen-producing tumors.

  • Risk Assessment: Evaluates breast cancer and cardiovascular disease risk.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Labrie F, Luu-The V, Labrie C, et al. Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocr Rev. 2003;24(2):152-182.
[2] Burger HG. The endocrinology of the menopause. Maturitas. 1996;23(2):129-136.
[3] Zumoff B. Hormonal profiles in obesity. Metabolism. 1995;44(9 Suppl 3):21-23.
[4] Cauley JA, Gutai JP, Kuller LH, et al. Endogenous estrogen levels and coronary artery disease in postmenopausal women. Am J Epidemiol. 1987;126(6):936-945.
[5] Beato M, Herrlich P, Schütz G. Steroid hormone receptors: many actors in search of a plot. Cell. 1995;83(6):851-857.
[6] Hankinson SE, Colditz GA, Willett WC. Towards an integrated model for breast cancer etiology: the lifelong interplay of genes, lifestyle, and hormones. Breast Cancer Res. 2004;6(5):213-218.
[7] Clemons M, Goss P. Estrogen and the risk of breast cancer. N Engl J Med. 2001;344(4):276-285.
[8] Key TJ, Appleby PN, Reeves GK, et al. Circulating sex hormones and breast cancer risk factors in postmenopausal women: reanalysis of 13 studies. Br J Cancer. 2011;105(5):709-722.
[9] Lippert TH, Seeger H, Mueck AO. Estradiol metabolism and malignant disease. Maturitas. 2000;37(1):1-8.
[10] Rinaldi S, Key TJ, Peeters PH, et al. Endogenous sex steroids and risk of breast cancer in postmenopausal women: reanalysis of nine prospective studies. J Natl Cancer Inst. 2002;94(8):606-616.
[11] Rothman KJ, Flanders D, Flegal KM, Freedman DS. The role of hormone replacement therapy in breast cancer risk. Epidemiology. 2003;14(4):535-541.
[12] Colditz GA, Rosner BA. Cumulative risk of breast cancer to age 70 years according to risk factor status: data from the Nurses' Health Study. Am J Epidemiol. 2000;152(10):950-964.
[13] Cauley JA, Lucas FL, Kuller LH, et al. Elevated serum estradiol and testosterone concentrations are associated with a high risk for breast cancer. Ann Intern Med. 1999;130(4 Pt 1):270-277.
[14] Endogenous Hormones and Breast Cancer Collaborative Group, Key TJ, Appleby PN, et al. Circulating sex hormones and breast cancer risk factors in postmenopausal women. Int J Cancer. 2002;106(6):927-929.

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