Description
Functions in the Body
Butyrate is a vital short-chain fatty acid (SCFA) produced when beneficial bacteria in the colon break down dietary fiber. It plays a critical role in maintaining gut health by acting as a fuel source for the colonocytes (cells lining the gut) and protecting the gut from harmful substances. Butyrate is known for its anti-inflammatory properties, helping to reduce inflammation in the digestive tract and lower the risk of developing inflammatory bowel diseases (IBD) such as Crohn’s disease and ulcerative colitis. Additionally, butyrate supports colon health by inhibiting the growth of tumors, which can reduce the risk of colon cancer. Its benefits extend to promoting a balanced gut microbiome, which is essential for maintaining digestive health and preventing gastrointestinal disorders. Regular consumption of fiber-rich foods like fruits, vegetables, and whole grains can naturally boost butyrate production, enhancing overall gut function and supporting long-term digestive wellness.
Deficiency Symptoms
A deficiency in butyrate may result in poor immune function and digestive problems, as butyrate supports gut health and serves as a key energy source for colon cells.
Synergy & Antagonism
Butyrate works synergistically with other short-chain fatty acids (SCFAs) like acetate and propionate to support gut health. No significant antagonistic interactions are reported.
BUTYRATE
Warnings
Be cautious when using butyrate supplements during pregnancy and breastfeeding. Consult a healthcare provider before use.
Food Sources
Butyrate is produced in the gut from the fermentation of dietary fiber and can be increased by consuming fiber-rich foods such as whole grains, barley, oats, apples, onions, berries, and citrus fruits.