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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Immunoglobulin E

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IGE

Description

"Immunoglobulin E" (IgE) test checks your blood for IgE antibodies, which are produced in response to allergens. It’s often used when allergic reactions, asthma symptoms, or skin conditions are present. Elevated levels may suggest sensitivity to environmental, food, or seasonal triggers. This test is helpful when skin testing isn’t possible or inconclusive. Results help doctors confirm allergies and build personalized treatment plans, including medications or immunotherapy. Ongoing testing supports allergy management and helps reduce long-term immune system stress.

"Immunoglobulin E" (IgE) test checks your blood for IgE antibodies, which are produced in response to allergens. It’s often used when allergic reactions, asthma symptoms, or skin conditions are present. Elevated levels may suggest sensitivity to environmental, food, or seasonal triggers. This test is helpful when skin testing isn’t possible or inconclusive. Results help doctors confirm allergies and build personalized treatment plans, including medications or immunotherapy. Ongoing testing supports allergy management and helps reduce long-term immune system stress.

Test Category

Antibodies

Procedure

Invasive

Sample Type

Blood – Serum

Units

International Units Per Milliliter

Procedure Category

Blood Draw

Test Group

Immune System Group

Test Group Description

Immune System Group: By evaluating various aspects of immune system function and health, this group offers insights into immune responses and related health considerations.

Optimal Range

For All Individuals:

  • Conventional Unit: Not Available

  • SI Unit: Not Available

Normal Range

For All Individuals:

  • Conventional Unit: 1.50–144.00 IU/mL

  • SI Unit: 1.50–144.00 IU/mL

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Alcoholism

  • Allergic rhinitis (Inflammation of the nasal passages due to allergies)

  • Asthma (Chronic inflammatory disease of the airways)

  • Bacterial infections

  • Eczema (Chronic inflammatory skin condition)

  • Food allergies

  • Nephrotic syndrome (Kidney disorder char...

Key Reasons For Testing

  • Allergic Conditions: Identifies elevated IgE levels in asthma, rhinitis, and eczema.

  • Parasitic Infections: Detects elevated levels in infections like helminthiasis.

  • Anaphylaxis Risk: Assesses risk for severe allergic reactions and guides prevention.

  • Atopic Dermatitis: Aids in diagnosing and monitoring eczema.

  • Immunodeficiency Disorders: Evaluates low IgE levels in conditions like hyper-IgE syndrome.

  • Immunotherapy Monitoring: Tracks IgE levels during allergy desensitization treatments.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Lommatzsch M, Speer T, Herr C, et al. IgE is associated with exacerbations and lung function decline in COPD. Respir Res. 2022;23(1):1.
[2] Gould HJ, Sutton BJ. IgE in allergy and asthma today. Nat Rev Immunol. 2008;8(3):205-217.
[3] Stone KD, Prussin C, Metcalfe DD. IgE, mast cells, basophils, and eosinophils. J Allergy Clin Immunol. 2010;125(2 Suppl 2).
[4] Johansson SG, Bennich H. Immunological studies of an atypical (myeloma) immunoglobulin. Immunology.1967;13(4):381-394.
[5] Finkelman FD, Hogan SP, Hershey GK, Rothenberg ME, Wills-Karp M. Importance of cytokines in murine allergic airway disease and human asthma. J Immunol. 2010;184(4):1663-1674.
[6] Burrows B, Martinez FD, Halonen M, Barbee RA, Cline MG. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N Engl J Med. 1989;320(5):271-277.
[7] Jansen DF, Rijcken B, Schouten JP, Kraan J, Weiss ST, Timens W. The relationship of skin test positivity, high serum total IgE level, and peripheral blood eosinophilia to symptomatic and asymptomatic airflow limitation. Am J Respir Crit Care Med. 1999;159(3):924-931.
[8] Oettgen HC, Geha RS. IgE in asthma and atopy: cellular and molecular connections. J Clin Invest. 1999;104(7):829-835.
[9] van Ree R, Aalberse RC. Specific IgE without clinical allergy. J Allergy Clin Immunol. 1995;96(1):43-52.
[10] Burney PG, Potts J, Kummeling I, et al. The prevalence and distribution of food sensitization in European adults. Allergy. 2014;69(3):365-371.
[11] Erwin EA, Woodfolk JA, Custis NJ, Platts-Mills TA. Animal dander and cockroach exposure in homes of children with asthma: quantification and molecular analysis of IgE-binding proteins. J Allergy Clin Immunol. 2003;112(4):879-885.

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