Total Protein-to-Creatinine Ratio (Urine)
P / C U
Description
"Total Protein-to-Creatinine Ratio (Urine)" test evaluates the amount of protein in your urine compared to creatinine to help detect kidney damage. It’s often ordered for individuals with diabetes, high blood pressure, or suspected kidney disease. Elevated ratios may indicate protein leakage and impaired kidney filtration. This test allows for non-invasive monitoring without needing a 24-hour collection. Doctors use results to guide treatment changes, such as medication or lifestyle shifts, and track kidney health over time.
Category
Proteins, Waste Metabolites
Procedure
Non-Invasive
Sample Type
Urine
Units
Ratio
Procedure Category
Collect, Measure
Test Group
Urine Test Group, Complete Kidney Group
Test Group Description
Complete Kidney Group: Comprehensive tests provide a thorough assessment of kidney function, yielding detailed insights into renal health and associated conditions. Urine Test Group: It encompasses a variety of tests aimed at evaluating urinary composition, protein levels, microscopic abnormalities, and microbial cultures, offering comprehensive insights into urinary health and potential related conditions.
Optimal Range
For All Individuals:
Conventional Unit: < 0.15 R
SI Unit: Not Applicable
Normal Range
For All Individuals:
Conventional Unit: < 0.2 R
SI Unit: Not Applicable
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Amyloidosis (Abnormal protein buildup in tissues)
ANCA-associated vasculitis (Autoimmune inflammation of blood vessels)
Berger's disease (Kidney disorder causing inflammation of small blood vessels)
Dehydration
Diabetic nephropathy (Kidney damage due to diabetes)
Glomerulonephritis (Inflam...
Key Reasons For Testing
Kidney Function Assessment: Evaluates kidney health, as elevated ratios reflect kidney dysfunction or damage.
Proteinuria Detection: Diagnoses proteinuria, a key marker for kidney disease and systemic conditions.
Diabetes Management: Monitors diabetic nephropathy, detecting early kidney damage in diabetes.
Preeclampsia Screening: Screens for preeclampsia in pregnancy to prevent complications.
Nephrotic Syndrome Diagnosis: Identifies nephrotic syndrome, a condition characterized by heavy proteinuria and related symptoms.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
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[8] Carter JL, Tomson CR, Stevens PE, Lamb EJ. Does urinary protein-creatinine ratio reflect 24-hour protein excretion accurately? A systematic review. Ann Clin Biochem. 2006;43(Pt 3):167-170.
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[11] Heerspink HJ, Gansevoort RT, Brenner BM, et al. Albuminuria as a surrogate endpoint in chronic kidney disease: Considerations for use in clinical practice. Kidney Int. 2010;78(10):981-986.