
Description
"Methylsulfonylmethane" (MSM) is a sulfur-based compound found in plants, animals, and human tissues, widely recognized for its joint-supporting properties. Contributing to collagen formation, it helps maintain skin elasticity and connective tissue strength. Its anti-inflammatory benefits assist in reducing pain and discomfort linked to arthritis. Besides joint health, MSM supports detoxification and immune resilience. Athletes favor MSM for muscle recovery and exercise-related inflammation. Frequently included in wellness regimens, MSM remains a key element in structural and metabolic health.
Functions in the Body
Category
Deficiency Symptoms
Since MSM is not an essential nutrient, there are no deficiency symptoms associated with its absence.
Synergists & Antagonists
MSM works synergistically with glucosamine and chondroitin to support joint health and cartilage repair. It also enhances the effects of vitamin C for collagen production. There are no significant antagonistic interactions reported for MSM.

Methylsulfonylmethane
Warnings
Caution is advised when using MSM during pregnancy or breastfeeding. High doses of MSM may cause gastrointestinal discomfort, such as bloating, nausea, or diarrhea. Consult a healthcare provider before use if taking blood-thinning medications or if you have known sensitivities.
Food Sources
MSM can be found in natural sources like milk, coffee, tomatoes, tea, alfalfa sprouts, leafy green vegetables, apples, and raspberries.
Time Frame
MSM can be taken at any time of day, with or without food. However, it’s often consumed with meals to reduce the potential for gastrointestinal discomfort.
Depleted By
There are no known dietary or lifestyle factors that deplete MSM.