Description
"N-Acetyl-D-Glucosamine" (NAG) is a glucose-derived compound naturally present in cartilage, connective tissue, and the gut lining. Playing a role in cartilage integrity, it aids in reducing inflammation and supporting mobility. Its protective effects extend to gut health, where it helps maintain mucosal lining stability. In dermatological applications, NAG promotes skin hydration and elasticity. By contributing to cellular repair, it assists in immune regulation. Integral to connective tissue maintenance, this compound plays a role in joint flexibility and structural resilience.
Functions in the Body
Category
Deficiency Symptoms
NAG is a non-essential nutrient synthesized in the body. Low levels may result in reduced cartilage repair, joint stiffness, and compromised gut lining integrity.
Synergists & Antagonists
NAG supports joint and cartilage health when combined with chondroitin, MSM, hyaluronic acid, and collagen. High doses may reduce the benefits of glucosamine sulfate due to overlapping metabolic pathways.
N-Acetyl-D-Glucosamine
Warnings
NAG should be used cautiously by individuals allergic to shellfish, as it is often derived from shellfish sources. While no major side effects are known, individuals with autoimmune conditions should consult a healthcare provider before use.
Food Sources
NAG is not found in significant amounts in food and is typically produced in the body or sourced from supplements.
Time Frame
NAG is most effective when taken in the morning or with meals to support joint mobility and gut health throughout the day.
Depleted By
As a non-essential nutrient, NAG levels may be reduced by chronic inflammation, joint damage, or gut disorders affecting glycosaminoglycan production.