
Description
"Pepsin" is a gastric enzyme secreted in the stomach, essential for breaking down dietary proteins into peptides. By activating in acidic conditions, it facilitates nutrient absorption in the small intestine. Its involvement in protein metabolism supports digestive efficiency and cellular repair. Furthermore, pepsin contributes to enzymatic stability and systemic function. For individuals with digestive concerns, it helps maintain gastrointestinal health. Naturally present in gastric secretions, pepsin remains fundamental to protein breakdown and digestive function.
Functions in the Body
Category
Deficiency Symptoms
A lack of pepsin can lead to digestive issues like bloating, upset stomach, burping, heartburn, and gas due to improper protein digestion.
Synergists & Antagonists
Pepsin works synergistically with other digestive enzymes like bromelain and trypsin to enhance protein breakdown. It can be antagonized by antacids, which reduce stomach acid and inhibit pepsin production.

Pepsin
Warnings
Consult a healthcare provider before taking pepsin supplements, especially if using antacids or experiencing low stomach acid. Pepsin may interact with medications that reduce stomach acidity, potentially diminishing its effectiveness.
Food Sources
Pepsin is an enzyme produced in the stomach and is not naturally found in foods.
Time Frame
Pepsin supplements are typically taken before meals to aid in protein digestion.
Depleted By
Pepsin production can be depleted by factors such as low stomach acid, antacids, antibiotics, diluting stomach acid with water or carbonated drinks, and poor sleep. Aging can also reduce natural pepsin production.