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Description
"Acetyl-L-Carnitine (ALC)" is a supplement derived from L-carnitine, a naturally occurring amino acid compound found in the body. It plays a key role in cellular energy production and is widely studied for its effects on neurological and metabolic health. ALC helps transport fatty acids into mitochondria, supporting physical endurance and cognitive function. It is commonly used for memory, focus, and fatigue reduction. Adding ALC to a supplement routine may help support long-term cognitive and metabolic health.
Category
Amino Acids
When To Take It
For best results, acetyl-L-carnitine is typically taken in the morning, as it can support energy metabolism and cognitive function throughout the day. Taking it earlier in the day helps avoid potential disruption of sleep due to increased energy levels.
Synergy and Antagonism
Acetyl L-carnitine works synergistically with CoQ10, alpha-lipoic acid, and omega-3 fatty acids, and other carnitine forms (l-carnitine, propionyl-l-carnitine) to enhance energy production and support mitochondrial health. There are no well-documented antagonistic interactions for acetyl L-carnitine.
Acetyl L-carnitine works synergistically with CoQ10, alpha-lipoic acid, and omega-3 fatty acids, and other carnitine forms (l-carnitine, propionyl-l-carnitine) to enhance energy production and support mitochondrial health. There are no well-documented antagonistic interactions for acetyl L-carnitine.

Acetyl-L-Carnitine
May Help With The Following Conditions
At present, there is no established association between this supplement and any medical condition listed on the Health Status pages.
Warnings
Certain antibiotics containing pivalic acid (e.g., pivampicillin, pivmecillinam) may deplete carnitine levels when metabolized. This is particularly important for individuals on valproic acid (an anticonvulsant), as both medications can interfere with carnitine metabolism. Monitoring carnitine levels may be necessary during long-term use, and supplementation can help maintain adequate levels.