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Description
"Type II Undenatured Collagen" is a supplement derived from chicken sternum cartilage and is often labeled as UC-II Collagen in joint support products. It plays a unique role by helping retrain immune tolerance to cartilage, making it especially effective for autoimmune or wear-related joint issues. Unlike hydrolyzed collagen, it works through immune modulation rather than tissue building. Even at low doses, it may reduce joint stiffness, improve mobility, and support long-term joint comfort in active or aging individuals.
Category
Additional Nutrients
When To Take It
Type II undenatured collagen should be taken on an empty stomach, typically once daily. Evening use may support overnight repair processes, though morning use is also acceptable.
Synergists and Antagonists
Type II collagen works well with compounds like curcumin, boswellia, MSM, and hyaluronic acid to promote joint comfort and mobility. It also complements omega-3 fatty acids and antioxidants in inflammation-focused protocols. However, combining it with large amounts of hydrolyzed collagen may interfere with its immune-modulating activity by triggering different biological responses.
Type II Undenatured Collagen
May Help With The Following Conditions
At present, there is no established association between this supplement and any medical condition listed on the Health Status pages.
Warnings
Individuals with poultry allergies should avoid this supplement. While generally well tolerated, it may take several weeks of consistent use to notice benefits.