Description
"Choline" is an essential nutrient naturally found in eggs, fish, and various plant-based foods. As a precursor to acetylcholine, it facilitates neurotransmitter signaling that supports nervous system function and cellular communication. It also plays a role in lipid metabolism, aiding fat transport and liver detoxification. Additionally, choline strengthens cell membrane integrity by maintaining structural stability. Recognized for its metabolic importance, choline remains essential for biochemical balance, energy production, and overall physiological health.
Functions in the Body
Category
Deficiency Symptoms
A deficiency in choline can lead to nonalcoholic fatty liver disease (NAFLD) and may also contribute to muscle damage and cognitive decline.
Synergists & Antagonists
Choline is often combined with vitamin B12, folate, and DHA for brain health and cognitive function. No significant antagonistic effects exist.
Choline
Warnings
Overdosing on choline can cause side effects such as vomiting, fishy body odor, and low blood pressure. Individuals with conditions that affect liver metabolism or blood pressure should consult a healthcare provider before supplementing.
Food Sources
Rich sources of choline include nutritional yeast, broccoli, green peas, eggs, fish, chicken, and shrimp.
Time Frame
Choline is best taken with meals to support optimal absorption and effectiveness.
Depleted By
Choline levels can be depleted by factors such as alcohol, anticonvulsants, anti-cancer medications, caffeine, antihistamines, antibiotics, antidepressants, and niacin treatments.