
Description
"N-Acetyl-L-Cysteine" (NAC) is a modified form of the amino acid L-cysteine, widely recognized for its role in glutathione production. Aiding in detoxification, NAC supports cellular defense against oxidative damage. Its respiratory benefits include reducing mucus buildup and inflammation in lung tissues. Beyond lung health, NAC contributes to cognitive function and neurotransmitter balance. Its detoxifying properties assist the liver in neutralizing environmental toxins. Frequently utilized in clinical and nutritional settings, NAC remains essential for oxidative stress protection.
Functions in the Body
Category
Deficiency Symptoms
Since NAC is not an essential nutrient, there are no deficiency symptoms associated with its absence.
Synergists & Antagonists
NAC is commonly used with glutathione, selenium, vitamin C, ALA, molybdenum, and glycine for antioxidant support and detoxification. No known antagonistic effects exist.

N-Acetyl-L-Cysteine
Warnings
If you have peptic ulcers or are taking medications that cause gastric lesions, avoid using NAC. Caution should be applied during breastfeeding. NAC interacts with insulin, nitroglycerin, and activated charcoal, so it should be used under medical supervision in these cases.
Food Sources
Rich sources of cysteine, which is converted to NAC in the body, include chicken, turkey, yogurt, cheese, eggs, sunflower seeds, and legumes.
Time Frame
It is recommended to take NAC before bed to support respiratory health and glutathione production.
Depleted By
NAC can be depleted by factors such as alcohol, antacids, nitrates, anti-emetics, anti-cancer medications, antivirals, antipsychotics, antibiotics, anti-depressants, analgesics, anti-inflammatory medications, NSAIDs, and opioids.