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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Vitamin K1

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VIT K1

Description

"Vitamin K1" test measures phylloquinone levels in your blood to evaluate clotting function and nutritional status. Deficiency can cause easy bruising, bleeding gums, or slow wound healing. Doctors use this test when symptoms suggest poor clotting or if liver disease is suspected. Low levels may result from malabsorption or dietary gaps. Based on results, treatment may include supplements or diet changes. Monitoring K1 supports cardiovascular health, bone strength, and proper blood clot formation.

"Vitamin K1" test measures phylloquinone levels in your blood to evaluate clotting function and nutritional status. Deficiency can cause easy bruising, bleeding gums, or slow wound healing. Doctors use this test when symptoms suggest poor clotting or if liver disease is suspected. Low levels may result from malabsorption or dietary gaps. Based on results, treatment may include supplements or diet changes. Monitoring K1 supports cardiovascular health, bone strength, and proper blood clot formation.

Category

Vitamins

Procedure

Invasive

Sample Type

Blood – Serum

Units

Nanograms per Milliliter | Nanomoles per Liter

Procedure Category

Blood Draw

Test Group

Vitamin Group, Complete Nutrient Deficiency Group, Coagulation Group

Test Group Description

Coagulation Group: These targeted tests are designed to assess clotting factors and coagulation pathways, offering valuable insights into hemostasis and thrombotic disorders. Complete Nutrient Deficiency Group: This comprehensive group includes an expanded panel of tests covering a wide range of vitamins, minerals, and other essential nutrients. Vitamin Group: This collection of tests encompasses a range of key vitamins crucial for physiological functions, aiding in nutritional status evaluation and deficiency detection.

Optimal Range

For All Individuals:

  • Conventional Unit: Not Available

  • SI Unit: Not Available

Normal Range

For All Individuals:

  • Conventional Unit: 0.10–2.20 ng/mL

  • SI Unit: 0.22–4.84 nmol/L

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Excessive vitamin K1 supplementation


Decreased levels may indicate:


  • Biliary atresia (Congenital liver and bile duct condition)

  • Celiac disease (Autoimmune disorder affecting the small intestine)

  • Cholestasis (Reduced bile flow)

  • Cirrhosis (Liver scarring)

  • Crohn's disease (Inflammatory bowel disease)

  • Dietary insufficiency

  • Gallstones (Hardened deposits in the gallbladder)

  • Hepatitis (Liver inflammation)

  • Medications (long-term use of antibiotics)

  • Ulcerative colitis (Inflammatory bowel disease)

Key Reasons For Testing

  • Blood Clotting: Evaluates vitamin K1’s role in synthesizing clotting factors essential for coagulation.

  • Coagulation Disorders: Diagnoses and manages conditions like vitamin K deficiency and liver-related clotting disorders.

  • Anticoagulant Therapy Monitoring: Guides dosing adjustments for anticoagulant therapies like warfarin.

  • Bone Health: Assesses risks like osteoporosis or fractures by evaluating calcium deposition in bones.

  • Liver Function: Provides insights into hepatic synthetic capacity and liver health.

  • Nutritional Assessment: Measures dietary sufficiency of vitamin K1 for nutritional adequacy.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Shearer MJ. Vitamin K in Health and Disease. Lancet. 1995;345(8944):229-234.

[2] Suttie JW. The Importance of Vitamin K in Human Nutrition. Annu Rev Nutr. 1995;15:399-417.

[3] Booth SL, Suttie JW. Dietary Intake and Adequacy of Vitamin K. J Nutr. 1998;128(5):785-788.

[4] Adams J, Pepping J. Vitamin K in Cancer Prevention. Am J Health Syst Pharm. 2005;62(15):1574-1581.

[5] Thijssen HH, Drittij-Reijnders MJ. Vitamin K Distribution in Rat Tissues: Dietary Phylloquinone Is a Source of Tissue Menaquinone-4. Br J Nutr. 1994;72(3):415-425.

[6] Schurgers LJ, Teunissen KJ, Hamulyak K, et al. Vitamin K-Containing Dietary Supplements: Comparison of Synthetic Phylloquinone and Natto-Derived Menaquinone-7. Blood. 2007;109(8):3279-3283.

[7] Vermeer C, Shearer MJ, Zittermann A, et al. Beyond Deficiency: Potential Benefits of Increased Intakes of Vitamin K for Bone and Cardiovascular Health. Eur J Nutr. 2004;43(6):325-335.

[8] Plaza SM, Lamson DW. Vitamin K2 in Bone Metabolism and Osteoporosis. Altern Med Rev. 2005;10(1):24-35.

[9] Knapen MH, Drummen NE, Smit E, et al. Three-Year Low-Dose Menaquinone-7 Supplementation Helps Decrease Bone Loss in Healthy Postmenopausal Women. Osteoporos Int. 2013;24(9):2499-2507.

[10] Rishavy MA, Berkner KL. Vitamin K Oxygenation, Glutamyl Carboxylation, and Their Implications for Human Health. Nutrients. 2018;10(8):1029.

[11] Davidson KW, Sadowski JA. Determination of Vitamin K1 in Plasma: Implications for Assessment of Vitamin K Status. Am J Clin Nutr. 1997;65(2):466-470.

[12] Stafford DW. The Vitamin K Cycle and Its Role in Blood Coagulation and Beyond. Protein Sci. 2005;14(2):275-282.

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