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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Aspartate Transaminase

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AST

Description

"Aspartate Transaminase" (AST) test measures the amount of AST enzyme in your blood, which can increase with liver, heart, or muscle injury. It’s commonly used to evaluate liver health, especially when combined with ALT testing. Elevated AST may indicate hepatitis, liver strain, or tissue damage elsewhere. Doctors use this test to interpret symptoms like fatigue or jaundice and decide whether further testing or treatment is needed. Ongoing AST monitoring helps track liver recovery or signal worsening function.

"Aspartate Transaminase" (AST) test measures the amount of AST enzyme in your blood, which can increase with liver, heart, or muscle injury. It’s commonly used to evaluate liver health, especially when combined with ALT testing. Elevated AST may indicate hepatitis, liver strain, or tissue damage elsewhere. Doctors use this test to interpret symptoms like fatigue or jaundice and decide whether further testing or treatment is needed. Ongoing AST monitoring helps track liver recovery or signal worsening function.

Category

Enzymes

Procedure

Invasive

Sample Type

Blood – Serum

Units

International Units Per Liter

Procedure Category

Blood Draw

Test Group

Complete Liver Group, Basic Liver Group, Male Health Group, Female Health Group, Complete Metabolic Group, Broad Metabolic Group, Complete Cardiovascular Group, Cognitive Health Group

Test Group Description

Basic Liver Group: This set of tests is fundamental for evaluating liver function and detecting common liver disorders. Broad Metabolic Group: This comprehensive set of tests extends beyond the basics, providing a thorough assessment of metabolic health with additional tests beyond the essentials. Cognitive Health Group: This group of tailored tests is aimed at evaluating cognitive function and assessing markers related to cognitive health, providing valuable insights for cognitive well-being and potential cognitive disorders. Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments. Complete Liver Group: A thorough array of tests aimed at assessing liver function, providing detailed insights into hepatic health and related conditions. Complete Metabolic Group: A comprehensive suite of tests designed to evaluate metabolic function, offering detailed insights into various aspects of metabolism and associated health conditions. Female Health Group: A comprehensive array of tests provides insights into various aspects of female health and wellness, aiding in the evaluation and management of overall health for females. Male Health Group: A comprehensive array of tests provides insights into various aspects of male health and wellness, aiding in the evaluation and management of overall health for men.

Optimal Range

For Men:

  • Conventional Unit: < 30.00 IU/L

  • SI Unit: < 30.00 IU/L


For Women:

  • Conventional Unit: < 26.00 IU/L

  • SI Unit: < 26.00 IU/L

Normal Range

For All Individuals:

  • Conventional Unit: 10.00–40.00 IU/L

  • SI Unit: 10.00–40.00 IU/L

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Cardiac conditions

  • Cholestasis (Impaired bile flow from the liver)

  • Cirrhosis (Chronic liver disease characterized by scarring of the liver)

  • Drug-related liver damage

  • Heat stroke

  • Hepatic metastasis (Spread of cancer to the liver)

  • Hepatic necrosis (Death of l...

Key Reasons For Testing

  • Liver Function Assessment: Measures AST levels to evaluate liver health and detect damage.

  • Liver Disease Diagnosis: Identifies conditions like hepatitis, cirrhosis, or fatty liver disease.

  • Muscle Injury Detection: Detects elevated AST levels linked to muscle damage or conditions like rhabdomyolysis.

  • Medication Monitoring: Tracks liver response to potentially hepatotoxic medications.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Chernecky CC, Berger BJ. Aspartate aminotransferase (AST, aspartate transaminase, SGOT) - serum. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:172-173.
[2] Pincus MR, Tierno PM, Gleeson E, Bowne WB, Bluth MH. Evaluation of liver function. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. St Louis, MO: Elsevier; 2017:21.
[3] Pratt DS. Liver chemistry and function tests. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:73.
[4] Giannini EG, Testa R, Savarino V. Liver enzyme alteration: a guide for clinicians. CMAJ. 2005;172(3):367-379.
[5] McGill MR. The past and present of serum aminotransferases and the future of liver injury biomarkers. EXCLI J.2016;15:817-828.
[6] Senior JR. Alanine aminotransferase: a clinical and regulatory tool for detecting liver injury-past, present, and future. Clin Pharmacol Ther. 2012;92(3):332-339.
[7] Lee TH, Kim WR, Benson JT, Therneau TM, Melton LJ. Serum aminotransferase activity and mortality risk in a United States community. Hepatology. 2008;47(3):880-887.
[8] Schindhelm RK, Diamant M, Dekker JM, et al. Alanine aminotransferase as a marker of nonalcoholic fatty liver disease in relation to obesity: the Hoorn Study. Diabetologia. 2006;49(1):30-36.
[9] Li G, Guo H, Zhao L, et al. Serum aminotransferase profiles and subsequent risk of mortality and cardiovascular events in a large cohort: a prospective study. J Clin Endocrinol Metab. 2019;104(8):3078-3086.
[10] Ozer JS, Ratner M, Shaw M, Bailey W, Schomaker S. The current state of serum biomarkers of hepatotoxicity. Toxicol Pathol. 2008;36(7):1078-1086.
[11] Rosenthal P. Assessing liver function and hyperbilirubinemia in the newborn. Clin Chem. 1997;43(1):228-234.

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