
Insulin Fasting

IF
Description
"Insulin Fasting" test measures insulin levels in your blood after an overnight fast, offering insight into how your body produces and uses insulin. It’s commonly used to detect insulin resistance, monitor type 2 diabetes, or evaluate metabolic syndrome. Elevated levels may indicate early metabolic dysfunction, while low levels could suggest pancreatic issues. Doctors use the results to shape a prevention or treatment plan, including dietary changes, physical activity, or medications that improve insulin sensitivity.
Test Category
Hormones
Procedure
Invasive
Sample Type
Blood – Serum
Units
Micro-International Units Per Milliliter | Picomoles Per Liter
Procedure Category
Blood Draw
Test Group
Complete Blood Sugar Group, Basic Blood Sugar Group, Complete Cardiovascular Group, Complete Metabolic Group
Test Group Description
Basic Blood Sugar Group: This group encompasses fundamental tests related to blood sugar, offering essential insights into glycemic control and metabolic health. Complete Blood Sugar Group: This expanded group includes a more comprehensive set of tests, offering a thorough evaluation of diverse facets of blood sugar levels for a more detailed understanding of metabolic health. Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments.
Optimal Range
For All Individuals:
Conventional Unit: 2.0–5.0 µIU/mL
SI Unit: 13.9–34.7 pmol/L
Normal Range
For All Individuals:
Conventional Unit: 2.6–24.9 µIU/mL
SI Unit: 18.1–172.9 pmol/L
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Insulin resistance (Reduced sensitivity to insulin)
Insulinomas (Insulin-producing tumors)
Obesity
Type 2 diabetes (Metabolic disorder characterized by high blood sugar levels)
Decreased levels may indicate:
Type 1 diabetes (Autoimmune condition resulting in insulin deficiency)
Key Reasons For Testing
Diabetes Screening: Identifies individuals at risk for diabetes mellitus, enabling early intervention.
Assessment of Insulin Sensitivity: Evaluates the body's response to insulin, aiding in the diagnosis of insulin resistance.
Monitoring Diabetes Treatment: Tracks the effectiveness of treatment regimens to ensure glycemic control.
Detection of Hypoglycemia: Identifies low insulin levels, aiding in hypoglycemia diagnosis.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
[1] Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab. 2008;294(1).
[2] Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia.1985;28(7):412-419.
[3] Munir KM, Chandrasekaran S, Gao F, Quon MJ. Insulin resistance in type 2 diabetes: multifactorial insights. Curr Diab Rep. 2013;13(6):1007-1016.
[4] Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care. 2004;27(6):1487-1495.
[5] Defronzo RA, Ferrannini E, Simonson DC. Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake. Metabolism. 1989;38(4):387-395.
[6] Kahn SE, Prigeon RL, McCulloch DK, et al. Quantification of the relationship between insulin sensitivity and β-cell function in human subjects. Evidence for a hyperbolic function. Diabetes. 1993;42(11):1663-1672.
[7] Abdul-Ghani MA, Tripathy D, DeFronzo RA. Contributions of β-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose. Diabetes Care. 2006;29(5):1130-1139.
[8] Shanik MH, Xu Y, Skrha J, Dankner R, Zick Y, Roth J. Insulin resistance and hyperinsulinemia: is hyperinsulinemia the cart or the horse? Diabetes Care. 2008;31(Suppl 2).
[9] Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Froguel P. Molecular mechanism of insulin resistance and obesity. Exp Biol Med (Maywood). 2003;228(10):1111-1117.
[10] Antuna-Puente B, Disse E, Rabasa-Lhoret R, Laville M, Capeau J, Bastard JP. How can we measure insulin sensitivity/resistance? Diabetes Metab. 2011;37(3):179-188.
[11] Gastaldelli A, Ferrannini E, Miyazaki Y, Matsuda M, DeFronzo RA. Thiazolidinediones improve β-cell function in type 2 diabetic patients. Am J Physiol Endocrinol Metab. 2007;292(3).
[12] Pories WJ, Swanson MS, MacDonald KG, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg. 1995;222(3):339-350.
[13] Templeman NM, Skovsø S, Page MM, Lim GE, Johnson JD. A causal role for hyperinsulinemia in obesity. J Endocrinol. 2017;232(3).
[14] Pratley RE, Weyer C. The role of impaired early insulin secretion in the pathogenesis of type II diabetes mellitus. Diabetologia. 2001;44(8):929-945.
[15] Haeckel R, Colic D, Wosniok W. Reference interval of serum insulin concentrations. Clin Chem Lab Med.2004;42(9):1069-1070.
[16] ter Horst KW, Gilijamse PW, Koopman KE, et al. Insulin resistance in obesity can be reliably identified from fasting plasma insulin. Int J Obes (Lond). 2015;39(12):1703-1709.
[17] Lee S, Choi S, Kim HJ, et al. Cutoff values of surrogate measures of insulin resistance for metabolic syndrome in Korean non-diabetic adults. J Korean Med Sci. 2006;21(4):695-700.