
Description
"Homocysteine" is an amino acid formed during the methionine cycle, playing a role in methylation, detoxification, and metabolic regulation. While essential for biochemical reactions, excessive levels can impact cardiovascular health and inflammatory balance. It supports circulatory efficiency and vascular integrity when it is accompanied by sufficient nutrients. The body also converts it into beneficial compounds involved in systemic regulation. Regulating homocysteine levels is essential for cardiovascular protection, inflammatory balance, and optimal biochemical function.
Functions in the Body
Category
Deficiency Symptoms
There are no direct deficiency symptoms for homocysteine, as it is a byproduct of amino acid metabolism.
Synergists & Antagonists
Homocysteine levels are antagonized by vitamins B2, B6, B9 (folate), B12, zinc, and trimethylglycine (TMG), which work synergistically to convert homocysteine into methionine or cysteine, preventing harmful accumulation.

Homocysteine
Warnings
Elevated homocysteine levels (hyperhomocysteinemia) may contribute to cardiovascular disease, cognitive decline, and osteoporosis. Individuals at risk should monitor levels and consult a healthcare provider before supplementation.
Food Sources
Homocysteine is not obtained from food but is a natural byproduct of protein metabolism in the body.
Time Frame
Not applicable, as homocysteine is not directly taken or consumed.
Depleted By
Homocysteine levels are not depleted by any external factors, as it is naturally produced in the body.