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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Oxidized Low-Density Lipoprotein Cholesterol

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OXLDL

Description

"Oxidized Low-Density Lipoprotein (OxLDL) Cholesterol" test evaluates levels of LDL cholesterol damaged by oxidative stress—a process that makes it more likely to contribute to arterial plaque. Elevated OxLDL may signal heightened risk for atherosclerosis or cardiovascular events. This test is especially useful for people with diabetes, high cholesterol, or early heart disease in the family. Based on results, your doctor may recommend antioxidants, medications, or lifestyle changes. Monitoring OxLDL levels helps promote arterial protection and prevent long-term damage.

"Oxidized Low-Density Lipoprotein (OxLDL) Cholesterol" test evaluates levels of LDL cholesterol damaged by oxidative stress—a process that makes it more likely to contribute to arterial plaque. Elevated OxLDL may signal heightened risk for atherosclerosis or cardiovascular events. This test is especially useful for people with diabetes, high cholesterol, or early heart disease in the family. Based on results, your doctor may recommend antioxidants, medications, or lifestyle changes. Monitoring OxLDL levels helps promote arterial protection and prevent long-term damage.

Category

Lipids, Proteins

Procedure

Invasive

Sample Type

Blood – Serum

Units

Units Per Liter

Procedure Category

Blood Draw

Test Group

Basic Cardiovascular Group, Complete Cardiovascular Group, Cardio Risk Group, Complete Inflammation Group, Complete Lipid Group

Test Group Description

Basic Cardiovascular Group: This group includes fundamental tests targeting essential markers related to cardiovascular health, providing foundational insights into cholesterol levels, blood pressure, and other key factors. Cardio Risk Group: This group focuses on assessing various markers associated with cardiovascular health and risk factors, aiding in the early detection and management of cardiovascular diseases. Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments. Complete Inflammation Group: Extensive tests offer a comprehensive assessment of inflammatory markers, yielding detailed insights into inflammation levels and related health conditions.

Optimal Range

For All Individuals:

  • Conventional Unit: 0.00–50.00 U/L

  • SI Unit: Not Applicable

Normal Range

For All Individuals:

  • Conventional Unit: 0.00–60.00 U/L

  • SI Unit: Not Applicable

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Diabetes (Metabolic disorder characterized by high blood sugar levels)

  • Environmental pollutant exposure

  • Genetic factors (APOE gene variants, genetic polymorphisms, or others)

  • High-transfat diet

  • Hypertension (High blood pressure)

  • Hypercholesterolemia (High levels of cholesterol in the blood...

Key Reasons For Testing

  • Oxidative Stress Marker: Reflects the oxidation of LDL particles, serving as an indicator of oxidative stress.

  • Atherosclerosis Development: Links to atherosclerosis progression by promoting inflammation and plaque formation.

  • Cardiovascular Risk Assessment: Assesses risk for coronary artery disease and cardiovascular events.

  • Diagnosis and Monitoring of Cardiovascular Disease: Provides additional insights into cardiovascular conditions beyond traditional lipid markers.

Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Steinberg D. Low density lipoprotein oxidation and its pathobiological significance. J Biol Chem. 1997;272(34):20963-20966.

[2] Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev. 2004;84(4):1381-1478.

[3] Itabe H, Obama T, Kato R. The dynamics of oxidized LDL during atherogenesis. J Lipids. 2011;2011:418313.

[4] Parthasarathy S, Santanam N, Ramachandran S, Meilhac O. Oxidized low-density lipoprotein: a possible marker for atherosclerosis. Ann N Y Acad Sci. 2000;899:282-291.

[5] Holvoet P, Vanhaecke J, Janssens S, Van de Werf F, Collen D. Oxidized LDL and the risk of coronary artery disease and acute myocardial infarction. Atherosclerosis. 2001;155(1):87-94.

[6] Tsimikas S. Oxidized low-density lipoprotein biomarkers in atherosclerosis. Curr Atheroscler Rep. 2006;8(1):55-61.

[7] Singh U, Jialal I. Oxidative stress and atherosclerosis. Pathophysiology. 2006;13(3):129-142.

[8] Ohmori R, Momiyama Y, Taniguchi H, et al. Plasma oxidized low-density lipoprotein and high-sensitivity C-reactive protein are independent risk factors for stenosis progression in patients with coronary artery disease. Atherosclerosis. 2005;178(1):239-244.

[9] Heinecke JW. Oxidized low-density lipoprotein: roles in atherogenesis and its measurement in human clinical studies. Am J Clin Nutr. 1997;65(5 Suppl):1606S-1610S.

[10] Yoshida H, Kisugi R. Mechanisms of LDL oxidation. Clin Chim Acta. 2010;411(23-24):1875-1882.

[11] Nishi K, Itabe H, Uno M, et al. Oxidized LDL in carotid plaques and plasma associates with plaque instability. Arterioscler Thromb Vasc Biol. 2002;22(10):1649-1654.

[12] Matsuura E, Kobayashi K, Tabuchi M, Lopez LR. Oxidative modification of low-density lipoprotein and immune regulation of atherosclerosis. Prog Lipid Res. 2006;45(6):466-486.

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