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Essential4Health

Get Healthy ~ Stay Healthy

Essential4Health

Get Healthy ~ Stay Healthy

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Apolipoprotein A1

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APO A1

Description

"Apolipoprotein A1" test measures levels of ApoA1, the main protein in HDL or “good cholesterol,” which helps transport cholesterol from arteries to the liver. Doctors use this test to assess heart disease risk, especially in those with high cholesterol or a family history of cardiovascular conditions. Low ApoA1 may indicate increased heart risk. Results guide lifestyle changes or medication strategies to improve lipid balance. Regular monitoring supports cardiovascular health and helps prevent complications over time.

"Apolipoprotein A1" test measures levels of ApoA1, the main protein in HDL or “good cholesterol,” which helps transport cholesterol from arteries to the liver. Doctors use this test to assess heart disease risk, especially in those with high cholesterol or a family history of cardiovascular conditions. Low ApoA1 may indicate increased heart risk. Results guide lifestyle changes or medication strategies to improve lipid balance. Regular monitoring supports cardiovascular health and helps prevent complications over time.

Test Category

Proteins, Lipids

Procedure

Invasive

Sample Type

Blood – Serum

Units

Milligrams Per Deciliter | Grams Per Liter

Procedure Category

Blood Draw

Test Group

Basic Cardiovascular Group, Complete Cardiovascular Group, Cardio Risk Group, Lipoprotein Group

Test Group Description

Basic Cardiovascular Group: This group includes fundamental tests targeting essential markers related to cardiovascular health, providing foundational insights into cholesterol levels, blood pressure, and other key factors. Cardio Risk Group: This group focuses on assessing various markers associated with cardiovascular health and risk factors, aiding in the early detection and management of cardiovascular diseases. Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments. Lipoprotein Group: This small group evaluates lipoprotein levels and related parameters, offering insights into lipid metabolism and cardiovascular health.

Optimal Range

For All Individuals:

  • Conventional Unit: 102.00–200.00 mg/dL

  • SI Unit: 1.02–2.00 g/L

Normal Range

For Men:

  • Conventional Unit: 110.00–180.00 mg/dL

  • SI Unit: 1.10–1.80 g/L


For Women:

  • Conventional Unit: 110.00–205.00 mg/dL

  • SI Unit: 1.10–2.05 g/L

Results That Differ From The Norm (Direct and Indirect Causes)

Increased levels may indicate:


  • Familial cholesteryl ester transfer protein deficiency (Genetic condition affecting cholesterol metabolism)

  • Familial hyperalphalipoproteinemia (Genetic condition characterized by high levels of alpha-lipoproteins)

  • Medications (such as estrogens and statins)

  • Niacin use (Use of niacin, a B vitamin, often used to improve cholesterol levels)

  • ...

Key Reasons For Testing

  • Cardiovascular Risk Assessment: Evaluates heart health, with higher ApoA1 levels linked to lower heart disease risk.

  • Lipid Profile Evaluation: Provides insights into HDL cholesterol and overall cholesterol health.

  • Atherosclerosis Prediction: Identifies low ApoA1 levels associated with a higher risk of clogged arteries.

  • Monitoring Treatment Response: Tracks ApoA1 changes to assess the effectiveness of cholesterol-lowering treatments or lifestyle adjustments.


Health Status Conditions It May Be Used To Assess

Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.

Some Prominent Medical Labs That May Offer This Test

Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.

References

Important Note

Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.


Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.

Disclaimer

This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.


Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.

[1] Sniderman AD, Couture P, Graaf JD. ApoA1, apoB, and cardiovascular disease risk: present and future utility. Curr Opin Lipidol. 2010;21(6):443-449.
[2] McQueen MJ, Hawken S, Wang X, et al. Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study. Lancet. 2008;372(9634):224-233.
[3] Walldius G, Jungner I, Holme I, Aastveit AH, Kolar W, Steiner E. High apolipoprotein B, low apolipoprotein A1, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. Lancet.2001;358(9298):2026-2033.
[4] Boekholdt SM, Arsenault BJ, Mora S, et al. Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis. JAMA.2012;307(12):1302-1309.
[5] Franceschini G, Sirtori CR, Capurso A, Weisgraber KH, Mahley RW. A-I Milano apolipoprotein: decreased high-density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family. J Clin Invest. 1980;66(5):892-900.
[6] Barter PJ, Rye KA. High-density lipoproteins and coronary heart disease. Atherosclerosis. 1996;121(1):1-12.
[7] Gordon DJ, Knoke J, Probstfield JL, Superko R, Tyroler HA. High-density lipoprotein cholesterol and coronary heart disease in hypercholesterolemic men. Circulation. 1986;74(6):1217-1225.
[8] Rader DJ, Haffner SM. Role of fibrates in reducing coronary risk and improving metabolic syndrome. Circulation.1999;100(7):576-578.
[9] Mahley RW, Innerarity TL, Rall SC Jr, Weisgraber KH. Plasma lipoproteins: apolipoprotein structure and function. J Lipid Res. 1984;25(12):1277-1294.

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