
Apolipoprotein B

APO B
Description
"Apolipoprotein B" test evaluates the level of ApoB, a key component of LDL or “bad cholesterol” that contributes to plaque buildup in arteries. It’s often ordered for individuals with high cholesterol or increased risk of heart disease. Elevated ApoB levels suggest higher cardiovascular risk and may call for treatment adjustments. The results help doctors tailor heart-healthy plans, including medications or diet changes. Tracking ApoB levels over time provides a clearer picture of lipid-related risk.
Test Category
Proteins, Lipids
Procedure
Invasive
Sample Type
Blood – Serum
Units
Milligrams Per Deciliter | Grams Per Liter
Procedure Category
Blood Draw
Test Group
Basic Cardiovascular Group, Complete Cardiovascular Group, Cardio Risk Group, Lipoprotein Group
Test Group Description
Basic Cardiovascular Group: This group includes fundamental tests targeting essential markers related to cardiovascular health, providing foundational insights into cholesterol levels, blood pressure, and other key factors. Cardio Risk Group: This group focuses on assessing various markers associated with cardiovascular health and risk factors, aiding in the early detection and management of cardiovascular diseases. Complete Cardiovascular Group: This group contains comprehensive tests for an extensive evaluation of cardiovascular health, providing thorough insights into heart-related conditions beyond basic assessments. Lipoprotein Group: This small group evaluates lipoprotein levels and related parameters, offering insights into lipid metabolism and cardiovascular health.
Optimal Range
For All Individuals:
Conventional Unit: < 90.00 mg/dL
SI Unit: < 0.90 g/L
Normal Range
For Men:
Conventional Unit: 55.00–125.00 mg/dL
SI Unit: 0.55–1.25 g/L
For Women:
Conventional Unit: 50.00–120.00 mg/dL
SI Unit: 0.50–1.20 g/L
Results That Differ From The Norm (Direct and Indirect Causes)
Increased levels may indicate:
Anorexia nervosa (Eating disorder characterized by restricted food intake)
Biliary obstruction (Blockage in the bile ducts)
Coronary artery disease (Narrowing or blockage of the coronary arteries)
Diabetes (Metabolic disorder characterized by high blood sugar levels)
Hemodialysis (Treatment for kidney failure involving bl...
Key Reasons For Testing
Cardiovascular Risk Assessment: Evaluates heart health, with high ApoB levels linked to greater heart disease risk.
Lipid Profile Evaluation: Provides insights into LDL cholesterol and its impact on cardiovascular health.
Atherosclerosis Prediction: Identifies high ApoB levels associated with an increased risk of clogged arteries.
Monitoring Treatment Response: Tracks ApoB changes to assess the effectiveness of cholesterol-lowering treatments or lifestyle modifications.
Health Status Conditions It May Be Used To Assess
Currently, this test is not directly associated with any conditions listed on the Health Status page. However, it may be included as part of a broader set of tests linked to specific health conditions.
Some Prominent Medical Labs That May Offer This Test
Please note that this particular test has not been associated with any of the listed prominent medical labs. We recommend enquiring with your private physician or nearest hospital to determine where this specific test can be performed.
References
Important Note
Any medical procedure yielding results outside the norm may be directly or indirectly linked to the conditions outlined on this page. Various factors, including genetics, medication and supplement usage, recent illnesses, pregnancy, pre-test eating, smoking, and stress, can impact the test's outcome. Additionally, factors like false positives, false negatives, inaccurate analyses, and others can influence results.
Reference ranges, which help healthcare professionals interpret medical tests, may vary depending on age, gender, and other factors. They may also differ between laboratories due to variations in instruments and methods used. Optimal ranges are designed for preventive purposes, aiming to identify trends and potential risks early, while normal ranges reflect conventional laboratory values indicating no current disease or pathology. Your healthcare practitioner may have specific reasons for testing that deviate from the usual or may interpret results differently based on individual circumstances. Proper interpretation typically involves considering clinical findings and other diagnostic tests. Hence, it is crucial to provide your healthcare professionals with a comprehensive medical history, consult with them for result interpretation, and follow their guidance for potential re-testing or additional diagnostics.
Disclaimer
This content is provided solely for informative and educational purposes. It is not intended as a substitute for medical advice or treatment from a personal physician. Regarding the interpretation of their medical test results and/or specific health questions, it is recommended that all readers and viewers consult their physicians or other qualified health professionals. The publisher is not responsible for any adverse health effects that may result from reading or following the information in this educational content. Before beginning any nutrition, supplement, or lifestyle program, all viewers, especially those taking prescription or over-the-counter medications, should consult their physician or health care practitioner.
Please note that while prominent lab names are included in this content, we cannot guarantee that these labs offer all the tests mentioned. For confirmation, individuals should contact the labs directly or consult their medical practitioners. The information provided reflects general knowledge at the time of publication and may not include recent updates or emerging research. Readers should verify details with qualified professionals to ensure the most up-to-date and accurate guidance.
[1] Sniderman AD, Furberg CD, Keech A, et al. Apolipoproteins versus lipids as indices of coronary risk and as targets for statin therapy. Lancet. 2003;361(9359):777-780.
[2] Walldius G, Jungner I. The apoB/apoA-I ratio: a strong, new risk factor for cardiovascular disease and a target for lipid-lowering therapy: a review of the evidence. J Intern Med. 2006;259(5):493-519.
[3] Barter PJ, Ballantyne CM, Carmena R, et al. Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/two-day workshop. J Intern Med. 2006;259(3):247-258.
[4] Cromwell WC, Otvos JD, Keyes MJ, et al. LDL particle number and risk of future cardiovascular disease in the Framingham Offspring Study - implications for LDL management. J Clin Lipidol. 2007;1(6):583-592.
[5] McQueen MJ, Hawken S, Wang X, et al. Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study. Lancet. 2008;372(9634):224-233.
[6] Genest J, McPherson R, Frohlich J, et al. Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendations. Can J Cardiol.2009;25(10):567-579.
[7] Mora S, Szklo M, Otvos JD, et al. LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2007;192(1):211-217.
[8] Mora S, Glynn RJ, Ridker PM. High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy. Circulation. 2014;129(12):1186-1194.
[9] Marcovina SM, Albers JJ, Kennedy H, et al. International Federation of Clinical Chemistry standardization project for measurements of apolipoproteins A-I and B. Clin Chem. 1991;37(10 Pt 1):1676-1682.
[10] Ginsberg HN. Lipoprotein physiology in nondiabetic and diabetic states. Relationship to atherogenesis. Diabetes Care. 1991;14(9):839-855.
[11] Millar JS, Cuchel M. ApoB metabolism in cardiovascular disease: recent advances in understanding its regulation and potential clinical implications. Curr Opin Lipidol. 2015;26(2):181-186.