
Description
"D-Mannose" is a naturally occurring simple sugar found in fruits such as cranberries, apples, and peaches, structurally similar to glucose. Unlike typical sugars, it bypasses standard metabolism and reaches the bladder, where it interacts with bacterial adhesion mechanisms. By binding to E. coli, D-mannose facilitates the removal of unwanted microbes from the urinary tract. It engages in carbohydrate-linked pathways that support cellular homeostasis. Recognized for its properties, D-mannose remains widely used in urinary health and metabolic balance.
Functions in the Body
Category
Deficiency Symptoms
Since d-mannose is not an essential nutrient, no deficiency symptoms are associated with its absence.
Synergists & Antagonists
D-Mannose works synergistically with cranberry extract and vitamin C to support urinary tract health. It may also work well with probiotics to maintain a healthy balance of bacteria in the urinary tract. No significant antagonistic interactions are documented.

D-Mannose
Warnings
High doses of d-mannose can cause diarrhea and nausea. Individuals with kidney issues or diabetes should consult a healthcare provider before using d-mannose, as it may affect blood sugar levels.
Food Sources
D-mannose is found naturally in fruits such as cranberries, blueberries, peaches, apples, and oranges, and vegetables like green beans, cabbage, and broccoli.
Time Frame
D-mannose can be consumed anytime, either in supplement form or as part of a balanced diet.
Depleted By
There are no known dietary or lifestyle factors that deplete d-mannose levels in the body.