
Kidney Stones

Description
This page has 60 references
"Kidney Stones" are solid mineral deposits that form in the kidneys when waste substances like calcium or uric acid become overly concentrated. These stones can block urine flow, causing sharp lower back pain, nausea, or blood in the urine. Dehydration and high-oxalate diets increase risk. Staying well-hydrated, limiting salt, and moderating animal protein can help prevent recurrence. Treatment depends on stone size and type, but prompt care supports kidney function and lowers the chance of painful recurrences.
Symptoms & Signs
Body System
Kidneys and Urinary System
Causes
Environmental Factors, Diet, Low Urine Volume, Genetics, Low Bodily pH
Things To Do
The dietary recommendations for kidney stones include:
hydration. Drinking large amounts of quality water, especially distilled water, helps dilute urine, prevent kidney stone formation, and flush out existing stones.
Drink water with freshly squeezed lemon juice. Citric acid is known to improve pain.
consume a whole-foods-based diet consisting of fresh vegetables and fruits, legumes, whole grains, and healthy fats.
incorporate foods rich in vitamin A, such as carrots, dark leafy greens, sweet potatoes, pumpkins, mangoes, papayas, etc.
foods containing vitamin B6, such as dark leafy greens, potatoes, pumpkins, avocados, carrots, etc.
foods rich in magnesium, such as dark leafy greens, cruciferous vegetables, bananas, seeds, whole grains, etc.
foods containing zinc, such as dairy products, pumpkin seeds, brown rice, kidney beans, broccoli, etc.
calcium-rich foods, such as
anti-inflammatory foods, such as fruits and vegetables, turmeric, garlic, ginger, seeds, a limited amount of fish, herbs, spices, etc.
Furthermore, try the following:
If you follow any fasting regimen, always drink plenty of fluids during that period. Hydration is key for kidney stone treatment.
regular low-intesity physical exercise. Walking, swimming, or cycling can speed up the time needed to pass a kidney stone.
maintain a healthy weight.
get enough restful sleep.
practice stress reduction techniques such as yoga, mindfulness, and meditation.
Things To Avoid
The following foods and products should be avoided for kidney stone problems:
processed, junk, and fast foods.
sugar, desserts, candy, sugary snacks, and beverages. Insulemic responses cause calcium excretion.
oxalates found in foods such as spinach, beetroot greens, celery, blueberries, strawberries, almonds, peanuts, cocoa, rhubarb, etc.
purine-containing foods, such as fish, seafood, shellfish, and meats.
beer, carbonated drinks, coffee, and black tea.
In cystine stones, avoid the amino acid L-cystine.
Watch out for salt intake. Sodium should be limited in people with kidney stones.
Watch out for animal protein. Do not eat excessive amounts of it if you have kidney stones.
dehydration.
Furthermore, avoid the following:
sedentary lifestyle.
chronic stress.
smoking.
being overweight and obese.
medications that impact the kidneys.
Supplements
Direct Support
(Most Helpful → Least Helpful)
These supplements directly affect kidney stones by inhibiting crystal formation, supporting mineral balance, or promoting the breakdown and flushing of stones.
Magnesium: Magnesium citrate helps prevent the crystallization of calcium oxalate in urine, reducing the risk of stone formation. It also impedes the absorption of dietary oxalate, contributing to overall kidney stone prevention.
Potassium: Potassium citrate acts as a urinary alkalinizer, reducing urine acidity and enhancing protective compounds like citrate. This helps lower calcium oxalate supersaturation and decreases the risk of stone recurrence.
Vitamin B6: Vitamin B6 helps lower the excretion of oxalate in urine, reducing the risk of calcium oxalate stone formation by keeping oxalate levels in check.
N-Acetyl-L-Cysteine [NAC]: N-acetyl-L-cysteine (NAC) reduces oxidative stress and inflammation in the kidneys, conditions that can contribute to stone formation. It also helps reduce calcium oxalate crystal aggregation, supporting kidney stone prevention.
Chondroitin: Chondroitin affects the surface of calcium oxalate crystals, potentially preventing their aggregation and deposition, thus helping to reduce the risk of kidney stone formation.
Vitamin D3/K2: Vitamin D3 enhances calcium absorption, while Vitamin K2 ensures that calcium is directed to bones rather than soft tissues like the kidneys. This calcium-balancing effect may help reduce the risk of kidney stone formation.
Indirect Support
(Most Helpful → Least Helpful)
These supplements do not target kidney stones directly but may support urinary tract health, reduce inflammation, or enhance hydration and detoxification.
Probiotics: Probiotics help break down oxalate in the gut, with strains like Oxalobacter formigenes reducing oxalate absorption and excretion in urine. This process lowers the risk of calcium oxalate stone formation.
Omega-3: Omega-3 fatty acids have anti-inflammatory properties that may reduce the risk of kidney stones. They help lower urinary oxalate levels and decrease calcium oxalate supersaturation, both key factors in stone prevention.
Vitamin E: Vitamin E’s antioxidant properties help reduce oxidative stress in the kidneys, protecting against conditions that favor kidney stone formation and reducing the risk of stone development.
Natural Compounds
These natural compounds may help manage kidney stones by supporting stone dissolution, improving urinary flow, or balancing mineral levels.
Apple Cider Vinegar: Apple cider vinegar contains acetic acid, which may help dissolve kidney stones and prevent new ones from forming by altering urine pH. Its mild diuretic effects promote increased urine flow, helping flush out the kidneys, while its anti-inflammatory properties may reduce urinary tract inflammation and pain.
Sodium Bicarbonate: Sodium bicarbonate raises urinary pH and may help prevent uric acid stones by neutralizing excess acidity. It’s used in urology to reduce stone risk in patients with acidic urine profiles.
Plant Extracts
Direct Support
(Most Helpful → Least Helpful)
These plant extracts directly support relief from kidney stones by promoting diuresis, reducing crystal aggregation, or relaxing the urinary tract.
Chanca Piedra Extract: Chanca piedra, known as the "stone breaker," inhibits the growth and aggregation of calcium oxalate crystals, helping prevent kidney stones. Its diuretic properties also assist in flushing out small stones and reducing the risk of stone formation.
Berberine: Berberine acts as an antioxidant, diuretic, and urinary alkalinizer. By reducing urinary calcium and oxalate levels, it helps prevent calcium oxalate stones from forming, contributing to kidney stone prevention.
Tribulus Terrestris Extract: Tribulus terrestris lowers the excretion of oxalate, calcium, and phosphate, addressing key factors in kidney stone formation. It also combats oxidative stress and restores antioxidant enzyme activity in kidney tissue, providing additional protection against stones.
Lemon Juice: Lemon juice or lime juice bind with calcium through its citrate content, helping to prevent the formation of kidney stones by reducing calcium crystal buildup.
Horsetail Extract: Horsetail is a natural diuretic that increases urine production, helping flush out excess minerals that contribute to kidney stone formation. Its antioxidant properties also protect the kidneys from oxidative stress, reducing stone risk.
Uva Ursi Extract: Uva ursi acts as a mild diuretic and urinary antiseptic, promoting increased urine flow and reducing urinary tract inflammation. It helps prevent mineral crystallization and supports the expulsion of small stones.
Indirect Support
(Most Helpful → Least Helpful)
These extracts do not act directly on kidney stones but may support liver and kidney function, reduce oxidative stress, or promote internal fluid balance.
Dandelion Root Extract: Dandelion root’s diuretic properties increase urine production, helping flush out the kidneys and reduce the risk of stone formation. It also supports liver and kidney detoxification, contributing to overall kidney health.
Parsley Extract: Parsley’s diuretic effects increase urine output, helping flush out toxins and minerals that may contribute to kidney stone formation. Its anti-inflammatory and antioxidant properties help protect the kidneys and urinary tract.
Cranberry Juice: Cranberry juice or extract helps acidify urine, reducing the risk of calcium stone formation. Its diuretic properties increase urine flow, flushing out the urinary tract and preventing mineral buildup that leads to stones.
Alternative Treatments
These alternative therapies support urinary health, promote kidney function, and assist the body in eliminating or preventing stone formation.
Ayurveda: Ayurvedic formulations, such as Gokshura (Tribulus terrestris), Punarnava (Boerhavia diffusa), and Varun (Crataeva nurvala), promote the breakdown and passage of kidney stones, especially smaller ones, through the urinary tract. They also help reduce stone size and alleviate symptoms like hematuria and urinary frequency.
Acupuncture: Acupuncture supports kidney and bladder meridian function, and clinical studies suggest it may reduce renal colic pain and improve urinary flow. Points like BL23 and KI3 are used to regulate kidney qi and promote smooth urination.
Functional Lab Tests You May Wish to Explore
Books Worth Considering for Deeper Insight
Currently, no high-quality books meeting our functional, integrative, and natural healing standards are available for this condition. As soon as trusted resources are published, we will review and feature them here.
Podcasts That Offer Valuable Perspectives
Currently, no high-quality books meeting our functional, integrative, and natural healing standards are available for this condition. As soon as trusted resources are published, we will review and feature them here.
Educational Videos To Learn From
How Key Nutrients Support the Body
Antioxidants: Antioxidants protect cells from oxidative stress caused by free radicals, potentially reducing the risk of chronic diseases such as cancer and cardiovascular ailments. They safeguard DNA integrity, slow down aging processes, and support overall cellular health.
Electrolytes: Electrolytes carry charged ions essential for transmitting nerve impulses, regulating muscle function, and maintaining fluid balance. They are pivotal in supporting hydration, nerve signaling, and overall physiological balance.
Fatty Acids: Fatty acids serve as energy sources, structural components of cell membranes, and precursors to signaling molecules. Essential fatty acids, like omega-3 and omega-6, play critical roles in brain function, cardiovascular health, and inflammation regulation.
Fruit Extracts: Rich in antioxidants, vitamins, and fiber, fruit extracts offer numerous health benefits, including anti-inflammatory, anti-cancer, and immune-boosting properties. They also support digestive health and contribute to overall well-being.
Herbal Extracts: Herbal extracts contain bioactive compounds with various medicinal properties, including antioxidant, anti-inflammatory, and antimicrobial effects. They have been used traditionally to support digestion, immunity, and overall health.
Minerals: Minerals are essential for various physiological functions, including bone health, nerve transmission, and enzyme activity. They support overall health by ensuring proper cellular function and metabolic processes.
Other Nutrients: Other nutrients encompass a wide array of essential compounds crucial for various physiological functions. This category includes neurotransmitters and their precursors, which facilitate nerve signaling and are vital for central nervous system function. Additionally, naturally occurring structural components and biological detergents, such as phospholipids and bile salts, play critical roles in tissue repair, fat digestion, and overall bodily function. Phospholipids contribute to cell membrane integrity and fat emulsification, while bile salts are key to digesting and absorbing dietary fats. Hormones and their precursors regulate numerous physiological processes, including metabolism, growth, and reproduction. Furthermore, naturally occurring chemicals and metals play pivotal roles in enzymatic reactions, immune function, and overall health maintenance.
Probiotics: Probiotics are live microorganisms that confer health benefits when consumed. They support gut health, immune function, and oral hygiene by promoting the growth of beneficial bacteria and inhibiting the growth of harmful pathogens.
Vitamins: Vitamins are essential micronutrients that play diverse roles in supporting cellular processes, immune function, and overall health. They must be obtained through diet or supplementation to ensure proper bodily function.
Essential Nutrients Explained
References
[1] Vitamin D Does Not Contribute to Kidney Stones, Study Asserts. UC San Diego Health: Newsroom. 2017, Oct.
[2] Malihi Z, Wu Z, Stewart AW, Lawes CM, Scragg R. Hypercalcemia, hypercalciuria, and kidney stones in long-term studies of vitamin D supplementation: a systematic review and meta-analysis. Am J Clin Nutr. 2016;104(4):1039-1051.
[3] Dowswell R. How to prevent kidney stones recurring. Nutritionist Resource. 2015, Mar.
[4] Li Y, Lu X, Yang B, et al. Vitamin K1 Inhibition of Renal Crystal Formation through Matrix Gla Protein in the Kidney. Kidney Blood Press Res. 2019;44(6):1392-1403.
[5] Cozzolino M, Mangano M, Galassi A, Ciceri P, Messa P, Nigwekar S. Vitamin K in Chronic Kidney Disease. Nutrients. 2019;11(1):168.
[6] What You Need to Know About Vitamin K2, D and Calcium: Dr. Mercola Interviews Dr. Kate Rheaume-Blue. Mercola.com. 2012, Dec.
[7] Laranjinha I, Matias P, Dickson J. Magnesium supplementation to prevent recurrence of renal stones. Port J Nephrol Hypert . 2019, Vol 33, Issue 4.
[8] Zerwekh JE, Odvina CV, Wuermser LA, Pak CY. Reduction of renal stone risk by potassium-magnesium citrate during 5 weeks of bed rest. J Urol. 2007;177(6):2179-2184.
[9] Azarfar A, Esmaeili M, Tousi N, et al. Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review. Reviews in Clinical Medicine. 2016, 3(1), 18-22.
[10] Sorkhi H, Saeedizand N, Poornasrollah M, Bijani A, Shafi H. Efficacy of potassium polycitrate on renal stone and microlithiasis predisposed by metabolic disorders. Caspian J Intern Med. 2017;8(4):296-300.
[11] Wiegand A, Fischer G, Seeger H, et al. Impact of potassium citrate on urinary risk profile, glucose and lipid metabolism of kidney stone formers in Switzerland, Clinical Kidney Journal. 2020, Vol 13, Issue 6, pp 1037–1048.
[12] Jaipakdee S, Prasongwatana V, Premgamone A, et al. The effects of potassium and magnesium supplementations on urinary risk factors of renal stone patients. J Med Assoc Thai. 2004;87(3):255-263.
[13] Harvard Medical School. The kidney stone diet: Not as restrictive as you may think. Harvard health Publishing. 2019, Nov.
[14] Gul Z, Monga M. Medical and dietary therapy for kidney stone prevention. Korean J Urol. 2014;55(12):775-779.
[15] Penniston KL, Steele TH, Nakada SY. Lemonade therapy increases urinary citrate and urine volumes in patients with recurrent calcium oxalate stone formation. Urology. 2007;70(5):856-860.
[16] Five Ways to Prevent Kidney Stones: From Lemonade to Surgery. UC San Diego Health: Newsroom. 2010, Apr.
[17] Aras B, Kalfazade N, Tuğcu V, et al. Can lemon juice be an alternative to potassium citrate in the treatment of urinary calcium stones in patients with hypocitraturia? A prospective randomized study. Urol Res. 2008, 36, 313.
[18] UT Southwestern Medical Center. Orange Juice Is Better Than Lemonade At Keeping Kidney Stones Away. ScienceDaily. 2006, Sept.
[19] Bashir S, Gilani AH. Antiurolithic effect of berberine is mediated through multiple pathways. Eur J Pharmacol. 2011;651(1-3):168-175.
[20] Wan X, Chen X, Liu L, Zhao Y, Huang WJ, et al. (2013) Berberine Ameliorates Chronic Kidney Injury Caused by Atherosclerotic Renovascular Disease through the Suppression of NFκB Signaling Pathway in Rats. PLOS ONE 8(3): e59794.
[21] Jyothilakshmi V, Thellamudhu G, Chinta R, et al. Beneficial antioxidative effect of the homeopathic preparation of Berberis vulgaris in alleviating oxidative stress in experimental urolithiasis. Forsch Komplementmed. 2014;21(1):7-12.
[22] Dissayabutra T, Kalpongnukul N, Chindaphan K, et al. Urinary sulfated glycosaminoglycan insufficiency and chondroitin sulfate supplement in urolithiasis. PLoS One. 2019;14(3):e0213180.
[23] Li JJ, Xue JF, Ouyang JM. Stabilization of Submicron Calcium Oxalate Suspension by Chondroitin Sulfate C May Be an Efficient Protection from Stone Formation. Bioinorganic Chemistry and Applications. 2013.
[24] Torshin IY, Lila AM, Limanova OA, Gromova OA. Prospects for the use of chondroitin sulfate and glucosamine sulfate with osteoarthritis associated with pathology of the kidneys and urinary system. 2020, Vol 13, Issue 1.
[25] Ferraro PM, Taylor EN, Gambaro G, Curhan GC. Vitamin B6 intake and the risk of incident kidney stones. Urolithiasis. 2018;46(3):265-270.
[26] Curhan GC, Willett WC, Speizer FE, Stampfer MJ. Intake of vitamins B6 and C and the risk of kidney stones in women. J Am Soc Nephrol. 1999;10(4):840-845.
[27] F. F. Faragalla, S. N. Gershoff, Interrelations among Magnesium, Vitamin B6, Sulfur and Phosphorus in the Formation of Kidney Stones in the Rat, The Journal of Nutrition, Volume 81, Issue 1, September 1963, Pages 60–66.
[28] Kamboj P, Aggarwal M, Puri S, Singla SK. Effect of aqueous extract of Tribulus terrestris on oxalate-induced oxidative stress in rats. Indian J Nephrol. 2011;21(3):154-159.
[29] Joshi VS, Parekh BB, Joshi MJ, Vaidya AD. Herbal extracts of Tribulus terrestris and Bergenia ligulata inhibit growth of calcium oxalate monohydrate crystals in vitro. J Crystal Growth. 2005;275:1403–8. [Google Scholar].
[31] Kaushik J, Tandon S, Bhardwaj R, et al. Delving into the Antiurolithiatic Potential of Tribulus terrestris Extract Through -In Vivo Efficacy and Preclinical Safety Investigations in Wistar Rats. Sci Rep. 2019;9(1):15969. Published 2019 Nov 4.
[32] Shirani, M., Arjaki, D., Kheiri, S. et al. An in vitro screening potential traditional medicinal plants for nephrolithiasis. Clin Phytosci 6, 66 (2020).
[33] Ortiz-Alvarado O, Miyaoka R, Kriedberg C, Leavitt DA, Moeding A, Stessman M, Monga M. Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid in the management of hypercalciuric stone formers. Urology. 2012 Feb 1;79(2):282-6.
[34] Rodgers AL, Siener R. The efficacy of polyunsaturated fatty acids as protectors against calcium oxalate renal stone formation: a review. Nutrients. 2020 Apr 12;12(4):1069.
[35] Bijarnia RK, Kaur T, Aggarwal K, Singla SK, Tandon C. Modulatory effects of N-acetylcysteine on hyperoxaluric manifestations in rat kidney. Food and chemical toxicology. 2008 Jun 1;46(6):2274-8.
[36] Ye M, Lin W, Zheng J, Lin S. N-acetylcysteine for chronic kidney disease: a systematic review and meta-analysis. American journal of translational research. 2021;13(4):2472.
[37] Hiremath S, Viswanathan P. Oxalobacter formigenes: a new hope as a live biotherapeutic agent in the management of calcium oxalate renal stones. Anaerobe. 2022 Jun 1;75:102572.
[38] Sidhu H, Allison MJ, Chow JM, Clark A, Peck AB. Rapid reversal of hyperoxaluria in a rat model after probiotic administration of Oxalobacter formigenes. The Journal of urology. 2001 Oct;166(4):1487-91.
[39] Thamilselvan S, Menon M. Vitamin E therapy prevents hyperoxaluria‐induced calcium oxalate crystal deposition in the kidney by improving renal tissue antioxidant status. Bju International. 2005 Jul;96(1):117-26.
[40] Huang HS, Chen J, Chen CF, Ma MC. Vitamin E attenuates crystal formation in rat kidneys: roles of renal tubular cell death and crystallization inhibitors. Kidney international. 2006 Aug 2;70(4):699-710.
[41] Narendra K, Swathi J, Sowjanya K, Satya AK. Phyllanthus niruri: A review on its ethno botanical, phytochemical and pharmacological profile J Pharm Res. 2012;5:4681–91
[42] Kamruzzaman HM, Hoq MO. A review on ethnomedicinal, phytochemical and pharmacological properties of Phyllanthus niruri. Journal of Medicinal Plants Studies. 2016;4(6):173-80.
[43] Carneiro DM, Freire RC, Honório TC, Zoghaib I, Cardoso FF, Tresvenzol LM, de Paula JR, Sousa AL, Jardim PC, Cunha LC. Randomized, Double‐Blind Clinical Trial to Assess the Acute Diuretic Effect of Equisetum arvense (Field Horsetail) in Healthy Volunteers. Evidence‐Based Complementary and Alternative Medicine. 2014;2014(1):760683.
[44] Carneiro DM, Jardim TV, Araújo YC, Arantes AC, de Sousa AC, Barroso WK, Sousa AL, da Cunha LC, Cirilo HN, Bara MT, Jardim PC. Equisetum arvense: new evidences supports medical use in daily clinic. Pharmacogn. Rev. 2019 Jul;13:50-8.
[45] Yarnell E. Botanical medicines for the urinary tract. World journal of urology. 2002 Nov;20:285-93.
[46] Locock RA. Bearberry [Herbal medicine]. Canadian Pharmacists Journal. 2000 Jun 1;133(5):38.
[47] Hook I, McGee A, Henman M. Evaluation of dandelion for diuretic activity and variation in potassium content. International Journal of Pharmacognosy. 1993 Jan 1;31(1):29-34.
[48] Yarnell E, Abascal K. Dandelion (Taraxacum officinale and T mongolicum). Integrative Medicine: A Clinician's Journal. 2009 Apr 1;8(2).
[49] Kreydiyyeh SI, Usta J. Diuretic effect and mechanism of action of parsley. Journal of ethnopharmacology. 2002 Mar 1;79(3):353-7.
[50] Punoševac M, Radović J, Leković A, Kundaković-Vasović T. A review of botanical characteristics, chemical composition, pharmacological activity and use of parsley. Archives of Pharmacy. 2021 Jun 7;71(Notebook 3):177-96.
[51] Singh KG, Ramya GS, Purohit D. In-vitro and ex-vivo studies on synergistic effects of Limonia acidissima and apple cider vinegar on anti-urolithiatic activity. Int. J. Pharm. Sci. Res. 2020;11:3347-54.
[52] Cupisti A, Giannese D, D’Alessandro C, Benedetti A, Panichi V, Alfieri C, Castellano G, Messa P. Kidney stone prevention: is there a role for complementary and alternative medicine?. Nutrients. 2023 Feb 9;15(4):877.
[53] McHarg T, Rodgers A, Charlton K. Influence of cranberry juice on the urinary risk factors for calcium oxalate kidney stone formation. BJU international. 2003 Nov;92(7):765-8.
[54] Kessler T, Jansen B, Hesse A. Effect of blackcurrant-, cranberry-and plum juice consumption on risk factors associated with kidney stone formation. European journal of clinical nutrition. 2002 Oct;56(10):1020-3.
[55] Kumaran MS, Patki PS. Evaluation of an Ayurvedic formulation (Cystone), in urolithiasis: A double blind, placebo-controlled study. European Journal of integrative medicine. 2011 Apr 1;3(1):23-8.
[56] Varsha S, Neelam S. Ashmari (Renal Stone) and its management in Ayurveda.
[57] Pinheiro VB, Baxmann AC, Tiselius HG, Heilberg IP. The effect of sodium bicarbonate upon urinary citrate excretion in calcium stone formers. Urology. 2013 Jul 1;82(1):33-7.
[58] Allie S, Rodgers A. Effects of calcium carbonate, magnesium oxide and sodium citrate bicarbonate health supplements on the urinary risk factors for kidney stone formation.
[59] Hodzic J, Golka K, Selinski S, Pourvali H, Sommerfeld HJ. Analgesia with acupuncture in extracorporeal shock wave lithotripsy of kidney stones–first results. Der Urologe. 2007 Jul;46:740-7.
[60] Tu JF, Cao Y, Wang LQ, Shi GX, Jia LC, Liu BL, Yao WH, Pei XL, Cao Y, Li HW, Yan SY. Effect of adjunctive acupuncture on pain relief among emergency department patients with acute renal colic due to urolithiasis: a randomized clinical trial. JAMA Network Open. 2022 Aug 1;5(8):e2225735-.